Results 11 to 20 of about 5,845 (176)

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co-Cultures Maintains Their Function in a Hypoxic Environment. [PDF]

Adv Healthc Mater
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Dani F, Duin S, Akkineni AR, Lehmann S, Ludwig B, Kühl M, Gelinsky M, Lode A.   +7 more
europepmc   +2 more sources

The Changing Landscape of Chronic Pancreatitis Research Trajectories Over Two Decades: A Global Meta-Analysis Using MeSH Terms. [PDF]

United European Gastroenterol J
ABSTRACT Objectives Significant progress has been made in research on chronic pancreatitis (CP). It is essential to analyze recent trends in this field to guide future clinical investigations. Methods Publications related to CP research from 2000 to 2023 were retrieved from PubMed.
Jiang LY, Wu C, Görgülü K, Lv YW, Algül H, Han C, Hu LH.   +6 more
europepmc   +2 more sources

Transplante isogênico de ilhotas de Langerhans no fígado de ratos: metodologia para separação e purificação das ilhotas de Langerhans Isogenic islet transplantation on the rat liver: Method for isolation and purification of the rat islets

Arquivos de Gastroenterologia, 2000
A maior indicação do transplante de pâncreas ou de ilhotas de Langerhans é o diabetes mellitus do tipo I. O processo deve suprir as necessidades de insulina mantendo os níveis glicêmicos dentro da normalidade.
Eleazar CHAIB, Apostolos PAPALOIS, Ingrid G. M. BRONS, Roy Y. CALNE   +3 more
doaj   +1 more source

In Vivo Imaging of Transplanted Pancreatic Islets

Frontiers in Endocrinology, 2018
The beta-cells in the islets of Langerhans in the pancreas secrete insulin and play an important role in glucose homeostasis. Diabetes, characterized by hyperglycemia, results from an absolute or a relative deficiency of the pancreatic beta-cell mass ...
Donghee Kim, Hee-Sook Jun, Hee-Sook Jun, Hee-Sook Jun   +3 more
doaj   +1 more source

Pancreas transplantation: an overview [PDF]

Einstein (São Paulo), 2010
Pancreas transplantation is the only treatment able to reestablish normal glucose and glycated hemoglobin levels in insulin-dependent diabetic patients without the use of exogenous insulin.
Andre Ibrahim David, Ben-Hur Ferraz-Neto, Fernando Levino, Roberto Ferreira Meirelles Junior, Álvaro Pacheco e Silva Filho   +4 more
doaj   +3 more sources

Generation of glucose-responsive functional islets with a three-dimensional structure from mouse fetal pancreatic cells and iPS cells in vitro. [PDF]

PLoS ONE, 2011
Islets of Langerhans are a pancreatic endocrine compartment consisting of insulin-producing β cells together with several other hormone-producing cells. While some insulin-producing cells or immature pancreatic cells have been generated in vitro from ES ...
Hiroki Saito, Masaki Takeuchi, Kazuhiro Chida, Atsushi Miyajima   +3 more
doaj   +1 more source

The effect of time and temperature on viability and performance of Langerhans islets separated from Balb/c mouse after death

Advanced Biomedical Research, 2015
Background: Tissue transplantation plays a pivotal role in the treatment of diseases. Pancreatic beta cell transplantation is the best way to obtain normal blood glucose in patients with diabetes type 1.
Rostam Ghorbani, Cyrus Jalili, Mohammad Reza Salahshoor, Maryam Shiasi   +3 more
doaj   +1 more source

Influence of the purification of human adult pancreatic islets on insulin secretion [PDF]

Vojnosanitetski Pregled, 2010
Background/Aim. The most effective method for human adult pancreatic islets purification is density-gradient centrifugation. The aim of this study was to analyze the effects of non-automated purification on preservation of functional capacity of human ...
Nikolić Dragan M., Đorđević Predrag B., Dimitrijević-Srećković Vesna, Džingalašević Marina, Belij Sandra, Kalezić Nevena   +5 more
doaj   +1 more source

Insulin Treatment of Mice Recipients Preserves β-Cell Function in Porcine Islet Transplantation

Cell Transplantation, 2002
Encapsulation of islets of Langerhans confers protection against cell-mediated immune destruction and so should allow the transplantation of islets without immunosuppression.
Oleg Pakhomov, Jiry Honiger, Edouard Gouin, Roland Cariolet, Gerard Reach, Sylviane Darquy Ph.D.   +5 more
doaj   +1 more source

Alotransplante de ilhotas de Langerhans no fígado de ratos submetidos a manipulação tímica com células dendríticas Alogenic islet transplantation on the rat liver after alogenic dendritic cells injection in the thymus

Arquivos de Gastroenterologia, 2005
RACIONAL: A maior indicação do transplante de pâncreas ou de ilhotas de Langerhans é o diabetes mellitus do tipo I. O processo deve suprir as necessidades de insulina, mantendo os níveis glicêmicos dentro da normalidade.
Eleazar Chaib, Apostolos Papalois, Ingrid G. M. Brons, Roy Y. Calne   +3 more
doaj   +1 more source