Results 21 to 30 of about 6,261 (168)

The effect of time and temperature on viability and performance of Langerhans islets separated from Balb/c mouse after death

Advanced Biomedical Research, 2015
Background: Tissue transplantation plays a pivotal role in the treatment of diseases. Pancreatic beta cell transplantation is the best way to obtain normal blood glucose in patients with diabetes type 1.
Rostam Ghorbani, Cyrus Jalili, Mohammad Reza Salahshoor, Maryam Shiasi   +3 more
doaj   +1 more source

Transplantation technologies for treatment of carbohydrate metabolism disorders

Вестник трансплантологии и искусственных органов, 2020
The review includes results of retrospective and prospective clinical studies (foreign and national) and guidelines on the use of transplantation technologies for treatment of type 1 diabetes and pancreatogenic diabetes in chronic pancreatitis and ...
V. Е. Zagainov, A. V. Meleshina, К. G. Korneva, S. А. Vasenin, E. V. Zagaynova   +4 more
doaj   +1 more source

In Vivo Imaging of Transplanted Pancreatic Islets

Frontiers in Endocrinology, 2018
The beta-cells in the islets of Langerhans in the pancreas secrete insulin and play an important role in glucose homeostasis. Diabetes, characterized by hyperglycemia, results from an absolute or a relative deficiency of the pancreatic beta-cell mass ...
Donghee Kim, Hee-Sook Jun, Hee-Sook Jun, Hee-Sook Jun   +3 more
doaj   +1 more source

Insulin Treatment of Mice Recipients Preserves β-Cell Function in Porcine Islet Transplantation

Cell Transplantation, 2002
Encapsulation of islets of Langerhans confers protection against cell-mediated immune destruction and so should allow the transplantation of islets without immunosuppression.
Oleg Pakhomov, Jiry Honiger, Edouard Gouin, Roland Cariolet, Gerard Reach, Sylviane Darquy Ph.D.   +5 more
doaj   +1 more source

A Supportive Role of Mesenchymal Stem Cells on Insulin-Producing Langerhans Islets with a Specific Emphasis on The Secretome

Biomedicines, 2023
Type 1 Diabetes (T1D) is a chronic autoimmune disease characterized by a gradual destruction of insulin-producing β-cells in the endocrine pancreas due to innate and specific immune responses, leading to impaired glucose homeostasis. T1D patients usually
Ronit Vogt Sionov, Ronit Ahdut-HaCohen
doaj   +1 more source

Pancreas transplantation: an overview [PDF]

Einstein (São Paulo), 2010
Pancreas transplantation is the only treatment able to reestablish normal glucose and glycated hemoglobin levels in insulin-dependent diabetic patients without the use of exogenous insulin.
Andre Ibrahim David, Ben-Hur Ferraz-Neto, Fernando Levino, Roberto Ferreira Meirelles Junior, Álvaro Pacheco e Silva Filho   +4 more
doaj   +3 more sources

Alotransplante de ilhotas de Langerhans no fígado de ratos submetidos a manipulação tímica com células não-parenquimatosas Allogenic islet transplantation on the rat liver after allogenic nonparenchymal cells injection in the thymus

Arquivos de Gastroenterologia, 2006
RACIONAL: A maior indicação do transplante de pâncreas ou de ilhotas de Langerhans é o diabetes mellitus do tipo I. O processo deve suprir as necessidades de insulina, mantendo os níveis glicêmicos dentro da normalidade OBJETIVOS: Estudar o ...
Eleazar Chaib, Apostolos Papalois, Ingrid G. M. Brons, Roy Y. Calne   +3 more
doaj   +1 more source

Label-free detection of insulin and glucagon within human islets of Langerhans using Raman spectroscopy. [PDF]

PLoS ONE, 2013
Intrahepatic transplantation of donor islets of Langerhans is a promising therapy for patients with type 1 diabetes. It is of critical importance to accurately monitor islet quality before transplantation, which is currently done by standard histological
Janneke Hilderink, Cees Otto, Cees Slump, Aufried Lenferink, Marten Engelse, Clemens van Blitterswijk, Eelco de Koning, Marcel Karperien, Aart van Apeldoorn   +8 more
doaj   +1 more source

Alotransplante de ilhotas de Langerhans no fígado de ratos submetidos a manipulação tímica com células dendríticas Alogenic islet transplantation on the rat liver after alogenic dendritic cells injection in the thymus

Arquivos de Gastroenterologia, 2005
RACIONAL: A maior indicação do transplante de pâncreas ou de ilhotas de Langerhans é o diabetes mellitus do tipo I. O processo deve suprir as necessidades de insulina, mantendo os níveis glicêmicos dentro da normalidade.
Eleazar Chaib, Apostolos Papalois, Ingrid G. M. Brons, Roy Y. Calne   +3 more
doaj   +1 more source

Generation of glucose-responsive functional islets with a three-dimensional structure from mouse fetal pancreatic cells and iPS cells in vitro. [PDF]

PLoS ONE, 2011
Islets of Langerhans are a pancreatic endocrine compartment consisting of insulin-producing β cells together with several other hormone-producing cells. While some insulin-producing cells or immature pancreatic cells have been generated in vitro from ES ...
Hiroki Saito, Masaki Takeuchi, Kazuhiro Chida, Atsushi Miyajima   +3 more
doaj   +1 more source