Results 21 to 30 of about 11,200 (227)

Insulin Treatment of Mice Recipients Preserves β-Cell Function in Porcine Islet Transplantation

open access: yesCell Transplantation, 2002
Encapsulation of islets of Langerhans confers protection against cell-mediated immune destruction and so should allow the transplantation of islets without immunosuppression.
Oleg Pakhomov   +5 more
doaj   +1 more source

Alotransplante de ilhotas de Langerhans no fígado de ratos submetidos a manipulação tímica com células dendríticas Alogenic islet transplantation on the rat liver after alogenic dendritic cells injection in the thymus

open access: yesArquivos de Gastroenterologia, 2005
RACIONAL: A maior indicação do transplante de pâncreas ou de ilhotas de Langerhans é o diabetes mellitus do tipo I. O processo deve suprir as necessidades de insulina, mantendo os níveis glicêmicos dentro da normalidade.
Eleazar Chaib   +3 more
doaj   +1 more source

From islet of Langerhans transplantation to the bioartificial pancreas

open access: yesLa Presse Médicale, 2022
Type 1 diabetes is a disease resulting from autoimmune destruction of the insulin-producing beta cells in the pancreas. When type 1 diabetes develops into severe secondary complications, in particular end-stage nephropathy, or life-threatening severe hypoglycemia, the best therapeutic approach is pancreas transplantation, or more recently ...
Thierry Berney   +8 more
openaire   +2 more sources

Macrophages in endocrine glands, with emphasis on pancreatic islets [PDF]

open access: yes, 2016
We review here the macrophages found in endocrine tissues, placing emphasis on those residing in the islets of Langerhans of the pancreas. The islets represent the endocrine organ where macrophages have been examined in great detail and where our own ...
Unanue, Emil R
core   +2 more sources

Lymphangiogenesis and angiogenesis during human fetal pancreas development [PDF]

open access: yes, 2014
Background: The complex endocrine and exocrine functionality of the human pancreas depends on an efficient fluid transport through the blood and the lymphatic vascular systems. The lymphatic vasculature has key roles in the physiology of the pancreas and
Carlotti, Françoise   +6 more
core   +1 more source

Multipotent mesenchymal stromal cells enhance insulin secretion from human islets via N-cadherin interaction and prolong function of transplanted encapsulated islets in mice

open access: yesStem Cell Research & Therapy, 2017
Background Multipotent mesenchymal stromal cells (MSC) enhance viability and function of islets of Langerhans. We aimed to examine the interactions between human MSC and human islets of Langerhans that influence the function of islets.
Elisa Montanari   +7 more
doaj   +1 more source

Engineering an endocrine Neo-Pancreas by repopulation of a decellularized rat pancreas with islets of Langerhans [PDF]

open access: yes, 2019
Introduction: Decellularization of pancreata and repopulation of these non-immunogenic matrices with islets and endothelial cells could provide transplantable, endocrine Neo-Pancreata.
Napierala, Hendrik
core   +1 more source

Alotransplante de ilhotas de Langerhans no fígado de ratos submetidos a manipulação tímica com células não-parenquimatosas Allogenic islet transplantation on the rat liver after allogenic nonparenchymal cells injection in the thymus

open access: yesArquivos de Gastroenterologia, 2006
RACIONAL: A maior indicação do transplante de pâncreas ou de ilhotas de Langerhans é o diabetes mellitus do tipo I. O processo deve suprir as necessidades de insulina, mantendo os níveis glicêmicos dentro da normalidade OBJETIVOS: Estudar o ...
Eleazar Chaib   +3 more
doaj   +1 more source

Classification of microscopy images of Langerhans islets [PDF]

open access: yes, 2014
Evaluation of images of Langerhans islets is a crucial procedure for planning an islet transplantation, which is a promising diabetes treatment. This paper deals with segmentation of microscopy images of Langerhans islets and evaluation of islet ...
Berková, Zuzana   +6 more
core   +1 more source

Islet Cell Transplantation: In Vivo and in Vitro Functional Assessment of Nonhuman Primate Pancreatic Islets

open access: yesCell Transplantation, 2000
Transplantation of pancreatic islets of Langerhans as a therapeutic approach for treatment of type I diabetes offers an alternative to subcutaneous insulin injections.
Alessandra Rammcoli   +7 more
doaj   +1 more source

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