Results 21 to 30 of about 12,558 (256)

Generation of glucose-responsive functional islets with a three-dimensional structure from mouse fetal pancreatic cells and iPS cells in vitro. [PDF]

PLoS ONE, 2011
Islets of Langerhans are a pancreatic endocrine compartment consisting of insulin-producing β cells together with several other hormone-producing cells. While some insulin-producing cells or immature pancreatic cells have been generated in vitro from ES ...
Hiroki Saito, Masaki Takeuchi, Kazuhiro Chida, Atsushi Miyajima   +3 more
doaj   +1 more source

Pancreatic islet transplantation after upper abdominal exeriteration and liver replacement [PDF]

, 1990
Nine patients who became diabetic after upper-abdominal exenteration and liver transplantation were given pancreatic islet-cell grafts obtained from the liver donor (eight cases), a third-party donor (one), or both (four). Two patients were diabetic when
Alejandro, R, Demetris, AJ, Fung, JJ, Mintz, DH, Ricordi, C, Starzl, TE, Todo, S, Tzakis, AG, Zeng, Y   +8 more
core   +1 more source

The effect of time and temperature on viability and performance of Langerhans islets separated from Balb/c mouse after death

Advanced Biomedical Research, 2015
Background: Tissue transplantation plays a pivotal role in the treatment of diseases. Pancreatic beta cell transplantation is the best way to obtain normal blood glucose in patients with diabetes type 1.
Rostam Ghorbani, Cyrus Jalili, Mohammad Reza Salahshoor, Maryam Shiasi   +3 more
doaj   +1 more source

Influence of the purification of human adult pancreatic islets on insulin secretion [PDF]

Vojnosanitetski Pregled, 2010
Background/Aim. The most effective method for human adult pancreatic islets purification is density-gradient centrifugation. The aim of this study was to analyze the effects of non-automated purification on preservation of functional capacity of human ...
Nikolić Dragan M., Đorđević Predrag B., Dimitrijević-Srećković Vesna, Džingalašević Marina, Belij Sandra, Kalezić Nevena   +5 more
doaj   +1 more source

Pancreas and islet cell transplantation [PDF]

, 2002
Currently, for the patient with type 1 diabetes, a definitive treatment without resorting to the use of exogenous insulin can be achieved only with pancreas or islet cell transplantation.
A.N. Balamurugan, Alexander, Allen, Amos, Barber, Barrou, Bartlett, Björk, Bonner-Weir, Brekke, Calne, Calne, Cameron, Cheung, Chow, Corry, Diem, Diem, DiLandro, Fontes, Giannoukakis, Giannoukakis, Gibson, Gliedman, Grey, Groth, Groth, Gu, Gupta, Harris, Hayek, Henry, Ilieva, Kelly, Kemp, Kendall, Kendall, Keymeulen, Kirk, Koike, Koike, Lacy, Lafferty, Lakey, Lillehei, London, Massimo Trucco, Mazariegos, Mintz, Murray, Najarian, Nghiem, Paraskevas, Petruzzo, Piehlmeier, Pipeleers-Marichal, Posselt, Prevost, Rajotte, Ramiya, Ramos, Ricordi, Rita Bottino, Robertson, Shapiro, Simeonovic, Solders, Sollinger, Sollinger, Sollinger, Soria, Ssobolew, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Stone, Stratta, Stratta, Sutherland, Suzuki, Tchervenivanov, Terasaki, Thomas E. Starzl, Tyden, Tzakis, Yasunami   +94 more
core   +1 more source

Islets of Langerhans Are Protected from Inflammatory Cell Recruitment during Reperfusion of Rat Pancreas Grafts [PDF]

, 2010
Background: Ischemia/reperfusion (I/R) injury plays a pivotal role in the development of graft pancreatitis, with ischemia time representing one of its crucial factors.
Eichhorn, M. E., Löhe, F., Massberg, S., Messmer, K., Preissler, G., Waldner, H., Winter, H.   +6 more
core   +1 more source

Insulin Treatment of Mice Recipients Preserves β-Cell Function in Porcine Islet Transplantation

Cell Transplantation, 2002
Encapsulation of islets of Langerhans confers protection against cell-mediated immune destruction and so should allow the transplantation of islets without immunosuppression.
Oleg Pakhomov, Jiry Honiger, Edouard Gouin, Roland Cariolet, Gerard Reach, Sylviane Darquy Ph.D.   +5 more
doaj   +1 more source

Alotransplante de ilhotas de Langerhans no fígado de ratos submetidos a manipulação tímica com células dendríticas Alogenic islet transplantation on the rat liver after alogenic dendritic cells injection in the thymus

Arquivos de Gastroenterologia, 2005
RACIONAL: A maior indicação do transplante de pâncreas ou de ilhotas de Langerhans é o diabetes mellitus do tipo I. O processo deve suprir as necessidades de insulina, mantendo os níveis glicêmicos dentro da normalidade.
Eleazar Chaib, Apostolos Papalois, Ingrid G. M. Brons, Roy Y. Calne   +3 more
doaj   +1 more source

Human islet isolation and allotransplantation in 22 consecutive cases [PDF]

, 1992
This report provides our initial experience in islet isolation and intrahepatic allotransplantation in 21 patients. In group 1, 10 patients underwent combined liver-islet allotransplantation following upper-abdominal exenteration for cancer.
Alejandro, R, Carroll, PB, Demetris, AJ, Fung, JJ, Mintz, DH, Ricordi, C, Rodriguez Rilo, HL, Shapiro, R, Starzl, TE, Tzakis, AG, Zeng, Y   +10 more
core   +1 more source

Potential benefits and risks of clinical xenotransplantation [PDF]

, 2012
The transplantation of organs and cells from pigs into humans could overcome the critical and continuing problem of the lack of availability of deceased human organs and cells for clinical transplantation.
Ayares, D, Cooper, DKC
core   +2 more sources