Results 31 to 40 of about 5,911 (222)

Encapsulation of Islets in Rough Surface, Hydroxymethylated Polysulfone Capillaries Stimulates VEGF Release and Promotes Vascularization after Transplantation

Cell Transplantation, 2005
The transplantation of encapsulated islets of Langerhans is one approach to treat type 1 diabetes without the need of lifelong immunosuppression. Capillaries have been used for macroencapsulation because they have a favorable surface-to-volume ratio and ...
N. Lembert, J. Wesche, P. Petersen, M. Doser, P. Zschocke, H. D. Becker, H. P. T. Ammon   +6 more
doaj   +1 more source

Epidemiology and Clinical Impact of Confirmed Respiratory Viral Infections in Solid Organ Transplant Recipients

Transplant Infectious Disease, EarlyView.
ABSTRACT Background Respiratory viral infections (RVIs) can have distinct clinical presentations and outcomes in non‐lung solid organ transplant (SOT) recipients compared to non‐transplant and lung transplant patients. Understanding their impact is crucial for improving patient care and outcomes.
Manon L. M. Prins, Ernst D. van Dokkum, Aiko P. J. de Vries, Maarten E. Tushuizen, Danny van der Helm, Edwin M. Spithoven, Irene M. van der Meer, Eduard M. Scholten, Albert M. Vollaard, Saskia le Cessie, Leo G. Visser, Geert H. Groeneveld   +11 more
wiley   +1 more source

Successful Suppression of the Early Rejection of Pig Islets in Monkeys

Cell Transplantation, 2000
Primary nonfunction (PNF) is seen very frequently after xenogeneic transplantation of islets of Langerhans. In a pig-to-rat model we recently observed that no PNF occurs when the islets are kept in culture at 37°C for 1–2 weeks prior to transplantation ...
Josephine K. R. A. Rijkelijkhuizen, Eelco Bouwman, Michel P. M. Van Der Burg, Jan Ringers, Miriam A. Ossevoort, Eva M. Kuhn, Pat Frost, Margreet Jonker   +7 more
doaj   +1 more source

Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation

Journal of Translational Medicine, 2007
While insulin replacement remains the cornerstone treatment for type I diabetes mellitus (T1DM), the transplantation of pancreatic islets of Langerhans has the potential to become an important alternative.
Li Xin, Harlan David M, Liu Eric, Wang Ena, Jin Ping, Ren Jiaqiang, Stroncek David F   +6 more
doaj   +1 more source

Applications of Multifunctional Hydrogel in Tissue Engineering and Regenerative Medicine

MedComm, Volume 7, Issue 2, February 2026.
Schematic illustration showing multifunctional hydrogels in the application of tissue engineering and regenerative medicine. ABSTRACT Hydrogels, with excellent hydrophilicity and high‐water content, have emerged as highly versatile biomaterials for tissue engineering and regenerative medicine.
Jieran Lyu, Xuemiao Liu, Qiqi Yang, Yuchang Zhang, Xing Wang   +4 more
wiley   +1 more source

Label-free detection of insulin and glucagon within human islets of Langerhans using Raman spectroscopy. [PDF]

PLoS ONE, 2013
Intrahepatic transplantation of donor islets of Langerhans is a promising therapy for patients with type 1 diabetes. It is of critical importance to accurately monitor islet quality before transplantation, which is currently done by standard histological
Janneke Hilderink, Cees Otto, Cees Slump, Aufried Lenferink, Marten Engelse, Clemens van Blitterswijk, Eelco de Koning, Marcel Karperien, Aart van Apeldoorn   +8 more
doaj   +1 more source

Rapid risk assessment on acute reference dose (ARfD) of cereulide in infants and information on acute consumption of infant formulae

EFSA Journal, Volume 24, Issue 2, February 2026.
Abstract EFSA has received a request for a rapid risk assessment for cereulide from the European Commission. Cereulide is a heat‐stable emetic toxin produced by Bacillus cereus, recently detected in infant formulae from multiple manufacturers. This led to precautionary recalls across several countries.
European Food Safety Authority (EFSA), Chantra Eskes, José Cortiñas‐Abrahantes, Bernard Bottex, Jean‐Lou C. M. Dorne, Bruno Dujardin, Rita Ferreira de Souza, Zsuzsanna Horvath, Eirini Kouloura, Luisa Ramos Bordajandi, Valentina Rizzi, Hans Steinkellner, Mary Gilsenan   +12 more
wiley   +1 more source

A Practical Guide to Rodent Islet Isolation and Assessment

Biological Procedures Online, 2009
Pancreatic islets of Langerhans secrete hormones that are vital to the regulation of blood glucose and are, therefore, a key focus of diabetes research. Purifying viable and functional islets from the pancreas for study is an intricate process.
Carter Jeffrey, Dula Stacey, Corbin Kathryn, Wu Runpei, Nunemaker Craig   +4 more
doaj   +3 more sources

A Practical Guide to Rodent Islet Isolation and Assessment Revisited

Biological Procedures Online, 2021
Insufficient insulin secretion is a key component of both type 1 and type 2 diabetes. Since insulin is released by the islets of Langerhans, obtaining viable and functional islets is critical for research and transplantation.
Kathryn L. Corbin, Hannah L. West, Samantha Brodsky, Nicholas B. Whitticar, William J. Koch, Craig S. Nunemaker   +5 more
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, Volume 600, Issue 2, Page 140-163, January 2026.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source