Results 31 to 40 of about 12,558 (256)

Macrophages in endocrine glands, with emphasis on pancreatic islets [PDF]

open access: yes, 2016
We review here the macrophages found in endocrine tissues, placing emphasis on those residing in the islets of Langerhans of the pancreas. The islets represent the endocrine organ where macrophages have been examined in great detail and where our own ...
Unanue, Emil R
core   +2 more sources

Multipotent mesenchymal stromal cells enhance insulin secretion from human islets via N-cadherin interaction and prolong function of transplanted encapsulated islets in mice

open access: yesStem Cell Research & Therapy, 2017
Background Multipotent mesenchymal stromal cells (MSC) enhance viability and function of islets of Langerhans. We aimed to examine the interactions between human MSC and human islets of Langerhans that influence the function of islets.
Elisa Montanari   +7 more
doaj   +1 more source

Effects of precipitation conditions on the membrane morphology and permeation characteristics [PDF]

open access: yes, 2009
[[abstract]]The permeability and permselectivity of asymmetric and particulate membranes towards glucose and proteins of various molecular sizes were studied.
Lin, Dong-tsamn
core   +1 more source

Alotransplante de ilhotas de Langerhans no fígado de ratos submetidos a manipulação tímica com células não-parenquimatosas Allogenic islet transplantation on the rat liver after allogenic nonparenchymal cells injection in the thymus

open access: yesArquivos de Gastroenterologia, 2006
RACIONAL: A maior indicação do transplante de pâncreas ou de ilhotas de Langerhans é o diabetes mellitus do tipo I. O processo deve suprir as necessidades de insulina, mantendo os níveis glicêmicos dentro da normalidade OBJETIVOS: Estudar o ...
Eleazar Chaib   +3 more
doaj   +1 more source

Islet Cell Transplantation: In Vivo and in Vitro Functional Assessment of Nonhuman Primate Pancreatic Islets

open access: yesCell Transplantation, 2000
Transplantation of pancreatic islets of Langerhans as a therapeutic approach for treatment of type I diabetes offers an alternative to subcutaneous insulin injections.
Alessandra Rammcoli   +7 more
doaj   +1 more source

Entrapment of Cultured Pancreas Islets in Three-Dimensional Collagen Matrices

open access: yesCell Transplantation, 1992
In vitro culture of islets of Langerhans decreases their immunogenecity, presumably by eliminating passenger leukocytes and other Ia+ presenting cells within the islets.
Seh-Huang Chao   +3 more
doaj   +1 more source

Stepwise Approach to Problematic Hypoglycemia in Korea: Educational, Technological, and Transplant Interventions [PDF]

open access: yesEndocrinology and Metabolism, 2017
Impaired awareness of hypoglycemia has been found to be prevalent in 20% to 40% of people with type 1 diabetes. If a similar prevalence exists in Koreans with type 1 diabetes, at a minimum, thousands of people with type 1 diabetes suffer at least one ...
Sang-Man Jin
doaj   +1 more source

The Eye as a Transplantation Site to Monitor Pancreatic Islet Cell Plasticity

open access: yesFrontiers in Endocrinology, 2021
The endocrine cells confined in the islets of Langerhans are responsible for the maintenance of blood glucose homeostasis. In particular, beta cells produce and secrete insulin, an essential hormone regulating glucose uptake and metabolism.
Erwin Ilegems   +5 more
doaj   +1 more source

Expression and function of alpha(v)beta(3) and alpha(v)beta(5) integrins in the developing pancreas: roles in the adhesion and migration of putative endocrine progenitor cells. [PDF]

open access: yes, 2000
Cell-cell and cell-matrix interactions play a critical role in tissue morphogenesis and in homeostasis of adult tissues. The integrin family of adhesion receptors regulates cellular interactions with the extracellular matrix, which provides three ...
Alpert   +67 more
core   +1 more source

Therapies for Type 1 Diabetes: Current Scenario and Future Perspectives

open access: yesClinical Medicine Insights: Endocrinology and Diabetes, 2019
Type 1 diabetes (T1D) is caused by autoimmune destruction of insulin-producing β cells located in the endocrine pancreas in areas known as islets of Langerhans. The current standard-of-care for T1D is exogenous insulin replacement therapy.
Varun Pathak   +4 more
doaj   +1 more source

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