Results 51 to 60 of about 11,200 (227)

Label-free detection of insulin and glucagon within human islets of Langerhans using Raman spectroscopy. [PDF]

open access: yesPLoS ONE, 2013
Intrahepatic transplantation of donor islets of Langerhans is a promising therapy for patients with type 1 diabetes. It is of critical importance to accurately monitor islet quality before transplantation, which is currently done by standard histological
Janneke Hilderink   +8 more
doaj   +1 more source

Potential benefits and risks of clinical xenotransplantation [PDF]

open access: yes, 2012
The transplantation of organs and cells from pigs into humans could overcome the critical and continuing problem of the lack of availability of deceased human organs and cells for clinical transplantation.
Ayares, D, Cooper, DKC
core   +2 more sources

Rodent monocyte‐derived macrophages do not express CD163: Comparative analysis using macrophages from living boreoeutherians

open access: yesDevelopmental Dynamics, Volume 255, Issue 4, Page 372-402, April 2026.
Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito   +9 more
wiley   +1 more source

A Practical Guide to Rodent Islet Isolation and Assessment Revisited

open access: yesBiological Procedures Online, 2021
Insufficient insulin secretion is a key component of both type 1 and type 2 diabetes. Since insulin is released by the islets of Langerhans, obtaining viable and functional islets is critical for research and transplantation.
Kathryn L. Corbin   +5 more
doaj   +1 more source

Effects of precipitation conditions on the membrane morphology and permeation characteristics [PDF]

open access: yes, 2009
[[abstract]]The permeability and permselectivity of asymmetric and particulate membranes towards glucose and proteins of various molecular sizes were studied.
Lin, Dong-tsamn
core   +1 more source

The Changing Landscape of Chronic Pancreatitis Research Trajectories Over Two Decades: A Global Meta‐Analysis Using MeSH Terms

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 3, April 2026.
ABSTRACT Objectives Significant progress has been made in research on chronic pancreatitis (CP). It is essential to analyze recent trends in this field to guide future clinical investigations. Methods Publications related to CP research from 2000 to 2023 were retrieved from PubMed.
Ling‐Ying Jiang   +6 more
wiley   +1 more source

The β-cell/EC axis: how do islet cells talk to each other? [PDF]

open access: yes, 2014
Author version made available in accordance with the publisher's policy.Within the pancreatic islet, the beta cell represents the ultimate biosensor.
Bonder, Claudine   +3 more
core   +1 more source

Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs‐On‐Chips

open access: yesAdvanced Biology, Volume 10, Issue 2, February 2026.
Buck and Bugter et al. explore the architectural diversity and physiological functions of human barrier systems and reveal how organ‐on‐chip platforms, particularly those integrating patient‐derived cells, are advancing barrier disease modeling. They highlight how emerging biological and technological advances can be used to bridge the gap between ...
Franziska Buck   +4 more
wiley   +1 more source

Ectopic Leptin Production by Intraocular Pancreatic Islet Organoids Ameliorates the Metabolic Phenotype of ob/ob Mice

open access: yesMetabolites, 2021
The pancreatic islets of Langerhans consist of endocrine cells that secrete peptide hormones into the blood circulation in response to metabolic stimuli. When transplanted into the anterior chamber of the eye (ACE), pancreatic islets engraft and maintain
Barbara Leibiger   +6 more
doaj   +1 more source

The Diabetic Dog as a Translational Model for Human Islet Transplantation. [PDF]

open access: yes, 2017
The dog model has served as the primary method for early development of many diabetes therapies, including pancreatic islet transplantation techniques and immunosuppressive protocols.
Adin, Christopher A, Gilor, Chen
core  

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