Results 61 to 70 of about 5,845 (176)
Intraocular in vivo imaging of pancreatic islet cell physiology/pathology
Molecular Metabolism, 2017 Background: Diabetes mellitus has reached epidemic proportions and requires new strategies for treatment. Unfortunately, the efficacy of treatment regimens on maintaining/re-gaining functional beta cell mass can, at the present, only be determined ...
Ingo B. Leibiger, Per-Olof Berggren
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Follow-up Study of the Revascularization Process of Purified Rat Islet Beta-Cell Grafts
Cell Transplantation, 1997 The revascularization of islets of Langerhans transplanted in heterotopic sites like the liver by portal vein embolization or the renal subcapsular space is a major process necessary for the viability of grafted cells.
José F. Mendola +6 more
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Xenotransplantation of Embryonic Pig Kidney or Pancreas to Replace the Function of Mature Organs
Journal of Transplantation, 2011 Lack of donor availability limits the number of human donor organs. The need for host immunosuppression complicates transplantation procedures. Ultrastructurally precise kidneys differentiate in situ following xenotransplantation in mesentery of ...
Marc R. Hammerman
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Clinical Trial Protocol for Porcine Islet Xenotransplantation in South Korea [PDF]
Diabetes & Metabolism JournalBackground Islet transplantation holds promise for treating selected type 1 diabetes mellitus patients, yet the scarcity of human donor organs impedes widespread adoption.
Byung-Joon Kim +18 more
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Encapsulation of Langerhans' islets: Microtechnological developments for transplantation
Engineering in Life Sciences, 2011 AbstractThere is an increasing trend to apply microsystems and microfluidics to solve medical and biomedical tasks. Microfluidic modules are used to modify and manipulate cells and cell clusters for therapeutic applications. Specifically, a method and technical system for encapsulation of Langerhans' islets as an option for the future treatment of ...
Stefan Wiedemeier +7 more
openaire +1 more source
Journal of Diabetes InvestigationAims/Introduction To investigate the long‐term efficacy of various encapsulated xenogeneic islet transplantation, and to explore the impact of different donor porcine genetic traits on islet transplantation outcomes.
Heon‐Seok Park +6 more
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Gelatin Density Gradient for Isolation of Islets of Langerhans
Cell Transplantation, 1998 Isolation of islets of Langerhans (islets) has been performed by means of collagenase digestion of the pancreatic tissue combined with density gradient separation of islets from unwanted exocrine tissues.
Tadashi Samejima +4 more
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The role of endothelial cells in pancreatic islet development, transplantation and culture
Frontiers in Cell and Developmental BiologyEndothelial cells (ECs) play pivotal roles in the development and maintenance of tissue homeostasis. During development, vasculature actively involves in organ morphogenesis and functional maturation, through the secretion of angiocrine factors and ...
Ajun Geng +5 more
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