Isocitrate dehydrogenase - Open Access .click

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Diagnosis and treatment of occipital brain lesions in children

Developmental Medicine &Child Neurology, EarlyView.
Occipital brain lesions in children represent a diagnostic challenge due to the large spectrum of etiologies and overlapping clinical features. This review analyses common and less common causes of occipital brain lesions in children, including malformative, vascular, genetic/metabolic, infectious, inflammatory, and neoplastic conditions.
Luca Bartolini +4 more
wiley +1 more source

Purification and properties of the nicotinamide–adenine dinucleotide phosphate-dependent isocitrate dehydrogenase from pig liver cytoplasm [PDF]

, 1970
John Illingworth, Keith F. Tipton
openalex +1 more source

Epilepsia, EarlyView.
Abstract Seizures are a common and challenging symptom in brain tumors, affecting approximately 60% of patients. Tumor‐related epilepsy (TRE) in glioma patients requires personalized and dynamic management in a multidisciplinary environment, especially for its intricate pathophysiology and unpredictable disease evolution. This investigation provides an
Roberto Michelucci +29 more
wiley +1 more source

Nalidixic Acid-Resistant Mutants of Escherichia coli Deficient in Isocitrate Dehydrogenase [PDF]

, 1971
Robert B. Helling, John S. Kukora
openalex +1 more source

ESTROGEN-SENSITIVE ISOCITRIC DEHYDROGENASE

Journal of Biological Chemistry, 1957
Dwain D. Hagerman, Claude A. Villee
openaire +3 more sources

Early seizure freedom with [18F]fluorodopa positron emission tomography response after isocitrate dehydrogenase inhibition with vorasidenib: First case report

Epilepsia, EarlyView.
Abstract Vorasidenib, a dual isocitrate dehydrogenase 1/2 (IDH1/2) inhibitor, showed superior efficacy in prolonging progression‐free survival and time to next intervention in IDH‐mutant grade 2 gliomas. This case is part of an ongoing institutional study exploring the impact of vorasidenib on seizure control and the potential of [18F]fluorodopa (F ...
Roberta Rudà +5 more
wiley +1 more source

Effects of mitochondrial NADP+-dependent isocitrate dehydrogenase deficiency on fructose-induced obesity in mice [PDF]

, 2018
Obesity prevalence in the United States continues to increase and is associated with health consequences such as type 2 diabetes, hypertension, atherosclerosis, and hyperlipidemia.
Beane, Kaleigh Elizabeth, Montalbano, Allison Michelle +1 more
core +2 more sources

THE ENZYMATIC PROPERTIES OF ISOCITRIC DEHYDROGENASE

Journal of Biological Chemistry, 1957
M. Carsiotis, G.W.E. Plaut, Guünther Siebert +2 more
openaire +3 more sources

Precision oncology to overcome resistance in R/R AML in children and adults requires combinations of cytotoxic, targeted, and immunological treatments

Journal of Internal Medicine, EarlyView.
Abstract Although outcomes for newly diagnosed acute myeloid leukaemia (AML) have been incrementally improved over the last decades, management of relapsed and refractory (R/R) AML remains a medical challenge. A curative intent for R/R AML usually involves chemotherapy (with or without targeted therapy) with subsequent consolidation, including ...
Martin Jädersten +7 more
wiley +1 more source

Properties of the nicotinamide adenine dinucleotide phosphate-specific isocitrate dehydrogenase from Blastocladiella emersonii [PDF]

, 1975
Ole C. Ingebretsen
openalex +1 more source

biochemistry
enzyme
biology

chemistry
gene
dehydrogenase

mutation
nad+ kinase
humans