Results 121 to 130 of about 68,056 (282)

Optic Chiasm and Bilateral Optic Nerve Oligodendroglioma in A 29‐Month‐Old German Shepherd

open access: yesVeterinary Ophthalmology, EarlyView.
ABSTRACT Objective To report the first documented case of high‐grade optic chiasm and nerve oligodendroglioma in a young dog and contribute to the comparative study of gliomas in humans and canines. Animal Studied A 29‐month‐old male intact German Shepherd.
Vienna M. Lunking   +7 more
wiley   +1 more source

A simulation study on the role of mitochondria‐sarcoplasmic reticulum Ca2+ interaction in cardiomyocyte energetics during exercise

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend An integrated model of human ventricular myocyte with excitation‐contraction‐energetics coupling was created to systematically analyse the contribution of Ca2+ regulation of mitochondrial enzymes to cardiomyocyte functions during workload transition; i.e. exercise.
Ayako Takeuchi, Satoshi Matsuoka
wiley   +1 more source

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma   +12 more
wiley   +1 more source

TE optimization for J‐difference editing of 2‐hydroxyglutarate at 3T

open access: yesMagnetic Resonance in Medicine, Volume 94, Issue 4, Page 1363-1376, October 2025.
Abstract Purpose To investigate the TE dependence of the edited 2‐hydroxyglutarate (2HG) signal, its separation from co‐edited glutamate plus glutamine (Glx), and fit accuracy in the presence of nuisance signals using a MEGA‐PRESS sequence. Methods Simulations were performed at TEs 70–160 ms to assess the signal intensity and 2HG‐Glx overlap as a ...
Kimberly L. Chan   +4 more
wiley   +1 more source

Biogenesis of Organelles and Membrane Proteins. [PDF]

open access: yes, 1988
Harmey, Matthew A.   +3 more
core   +1 more source

MRI for biology‐guided radiation therapy: Are we there yet? A summary of the 2024 ISMRM member‐initiated session

open access: yesMagnetic Resonance in Medicine, Volume 94, Issue 4, Page 1672-1683, October 2025.
Abstract At the 2024 ISMRM Annual Meeting in Singapore, a member‐initiated session on MRI for biology‐guided radiation therapy (RT), endorsed by the ISMRM MR in RT Study Group, was successfully organized. The session convened a diverse group of global experts in quantitative MRI for RT, who presented the latest research on the technical development and
Sirisha Tadimalla   +12 more
wiley   +1 more source

MYCN amplification defines an aggressive phenotype in IDH‐mutant gliomas

open access: yesThe Journal of Pathology: Clinical Research, Volume 11, Issue 5, September 2025.
Abstract In alignment with the latest WHO classification system, which underscores the integration of molecular alterations in glioma diagnosis and grading, this study investigates the prognostic significance of MYCN amplification in IDH‐mutant gliomas, a relationship that remains poorly characterized despite its established association with adverse ...
Xujun Xie   +5 more
wiley   +1 more source

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