Results 141 to 150 of about 68,056 (282)

Glucose Metabolic Reprogramming in Colorectal Cancer: From Mechanisms to Targeted Therapy Approaches

Cancer Medicine, Volume 14, Issue 17, September 2025.
ABSTRACT Background Colorectal cancer (CRC) is one of the most common malignant tumors, and its morbidity ranks third among all cancers, with a trend toward younger patients. Metabolic reprogramming, a unique metabolic mode in tumor cells, is closely related to the occurrence and development of CRC. Numerous studies have confirmed that many genetic and
Runkai Zhou, Fazhi Wang, Jiazhe Wen, Xuefeng Zhou, Yugang Wen   +4 more
wiley   +1 more source

Isocitrate dehydrogenase-mutant astrocytoma in persons aged 55 years and older: Survival differences versus the young. [PDF]

J Neuropathol Exp Neurol
Siddiq Z, Gilani A, Ung TH, Kleinschmidt-DeMasters BK.   +3 more
europepmc   +1 more source

Anti-Apoptotic and Anti-Oxidant Proteins in Glioblastomas: Immunohistochemical Expression of Beclin and DJ-1 and Its Correlation with Prognosis. [PDF]

, 2019
Arcidiacono Biagio, Borrelli Giorgio, Cappabianca Paolo, Del Basso De Caro Marialaura, Donato Annalidia, Donato Giuseppe, Guadagno Elia, Malara Natalia, Pignatiello Sara, Presta Ivan, Solari Domenico, Somma Teresa   +11 more
core   +1 more source

Gilteritinib in FLT3‐mutated acute myeloid leukemia: A real‐world Italian experience

Cancer, Volume 131, Issue 17, 1 September 2025.
Abstract Background and Methods This real‐world study evaluated the clinical effectiveness of gilteritinib in 205 patients with relapsed or refractory (R/R) FLT3‐mutated acute myeloid leukemia (AML) enrolled in the Italian expanded access since January 2018.
Roberto Cairoli, Lorenzo Del Castello, Silvia Imbergamo, Elisabetta Pierdomenico, Cristina Papayannidis, Erika Borlenghi, Calogero Vetro, Patrizia Chiusolo, Monica Fumagalli, Clara Minotti, Francesco Marchesi, Massimo Bernardi, Pellegrino Musto, Nicola Fracchiolla, Anna Candoni, Monia Lunghi, Maurizio Musso, Fabio Guolo, Donato Mannina, Albana Lico, Anna Maria Scattolin, Monica Crugnola, Sara Galimberti, Gianpaolo Nadali, Mauro Turrini, Patrizia Zappasodi, Elisabetta Todisco, Claudia Basilico, Giovanni Grillo, Valentina Mancini, Marta Riva, Davide Paolo Bernasconi, Rosa Greco   +32 more
wiley   +1 more source

Metal coordination and enzymatic reaction of the glioma-target R132H isocitrate dehydrogenase 1: Insights by molecular simulations. [PDF]

PLoS One
Raghavan B, De Vivo M, Carloni P.
europepmc   +1 more source

Control of metabolic interconversion of isocitrate dehydrogenase between the catalytically active and inactive forms in Escherichia coli [PDF]

, 1998
E.M.T. El-Mansi
openalex   +1 more source

The utility of next‐generation sequencing in metastatic prostate cancer FNA biopsies

Cancer Cytopathology, Volume 133, Issue 9, September 2025.
ABSTRACT Background Current American Society of Clinical Oncology guidelines state that patients with metastatic prostate cancer (MPC) should undergo germline and somatic DNA sequencing. The authors examined the utility of next‐generation sequencing (NGS) on fine‐needle aspiration (FNA) biopsies in which NGS was performed on cell block (CB) and/or ...
Deepika Sirohi, Chien‐Kuang Cornelia Ding, Bradley A. Stohr, Ronald Balassanian, Poonam Vohra, Rahul Aggarwal, Emily Chan, Nancy Y. Greenland   +7 more
wiley   +1 more source

Enzyme response to thyrotoxicosis and hypothyroidism in human liver and muscle [PDF]

, 1972
Bachmaier, B., Kiefhaber, P., Nolte, J., Pette, D., Schneider, H., Scriba, Peter Christian   +5 more
core  

Studies on the physiology and metabolism of hydrocarbon-utilizing microorganisms. XVII. Partial purification and some kinetic properties of NAD-linked and NADP-linked isocitrate dehydrogenases from Candida tropicalis.

, 1977
Shigeyasu Nabeshima, Saburo Ishiyama, Atsuo Tanaka, Saburo Fukui   +3 more
openalex   +2 more sources

Mitochondrial localization of a NADR-dependent isocitrate dehydrogenase isoenzyme by using the green fluorescent protein as a marker [PDF]

, 1998
Susana Gálvez, O. García Roché, E. Bismuth, Spencer C. Brown, Pierre Gadal, Michael Hodges   +5 more
openalex   +1 more source