Results 141 to 150 of about 358,941 (349)

Artificial intelligence‐assisted theranostics for brain tumors: Advancements and future perspectives

VIEW, EarlyView.
Graphical demonstration of different applications of AIT for brain tumor. The major applications include CT and MRI‐based segmentation and analysis, histopathological analysis, precision treatment planning and prognosis, surgical and radiotherapy optimization, real‐time intratreatment monitoring, biomarker discovery, and molecular profiling for ...
Mifang Li, Lingyan Zhang, Zia Ullah, Yinghe Zhang, Shengxue Wei, Lihe Huang, Bing Guo   +6 more
wiley   +1 more source

Effects of mitochondrial NADP+-dependent isocitrate dehydrogenase deficiency on fructose-induced obesity in mice [PDF]

, 2018
Obesity prevalence in the United States continues to increase and is associated with health consequences such as type 2 diabetes, hypertension, atherosclerosis, and hyperlipidemia.
Beane, Kaleigh Elizabeth, Montalbano, Allison Michelle   +1 more
core   +2 more sources

Radiomic model for predicting mutations in the isocitrate dehydrogenase gene in glioblastomas

OncoTarget, 2017
The present study proposed a computer-aided diagnosis system based on radiomic features extracted through magnetic resonance imaging to determine the isocitrate dehydrogenase status in glioblastomas.
K. Hsieh, Cheng-Yu Chen, Chung-Ming Lo
semanticscholar   +1 more source

Integrated multi‐omics analysis reveals metabolic reprogramming as a key driver of angiotensin II‐induced vascular remodeling

VIEW, EarlyView.
This study investigates the molecular alterations underlying angiotensin II (Ang II)‐induced vascular remodeling in cardiovascular diseases using a multi‐omics approach. Through data exploration and integrated multi‐omics analysis, our findings reveal that Ang II‐driven vascular injury in vascular smooth muscle cells is mediated by metabolic ...
Yiwei Hu, Dan Zhao, Lingyan Zhong, Jianxujie Zheng, Dongxue Zhang, Enhui Wu, Qian Shi, Liang Qiao, Ling Lin   +8 more
wiley   +1 more source

How robust are the data in vorasidenib for isocitrate dehydrogenase-1 or isocitrate dehydrogenase-2 mutant low-grade glioma?

Glioma, 2023
Eric T Wong
doaj   +1 more source

Extraneural and extracranial metastatic astrocytoma with primitive neuroectodermal component: a case report

Journal of Medical Case Reports
Background Astrocytoma is a highly malignant tumor of the central nervous system with limited survival, despite standard multimodal therapies. While typically remains confined to the central nervous system, rare instances of extraneural and extracranial ...
Frayne Gomez, Stephen Evans, Forough Foroughi, Narayan Karanth   +3 more
doaj   +1 more source

Mitochondrial Isocitrate Dehydrogenases from Yeast

Journal of Biological Chemistry, 1966
Abstract A polarographic technique suitable for kinetic studies of either isolated or bound pyridine nucleotide-linked dehydrogenases was used to investigate the isocitrate dehydrogenases of yeast mitochondria. Intact mitochondria were found to contain both triphosphopyridine nucleotide- and diphosphopyridine nucleotide-linked isocitrate dehydrogenases
C, Bernofsky, M F, Utter
openaire   +2 more sources

Application of 23Na MRI at 7 Tesla in distinguishing IDH genotype, P53 phenotype, and Ki‐67 LI in adult‐type diffuse gliomas

VIEW, EarlyView.
Abstract Background: The diagnostic performance of ultra‐high‐field 23Na magnetic resonance imaging (MRI) in predicting the P53 phenotype and Ki‐67 labeling index (LI) in adult‐type diffuse gliomas is still unknown. No studies have compared its diagnostic efficacy with diffusion weighted imaging (DWI) for distinguishing isocitrate dehydrogenase (IDH ...
Letian Yuan, Chaofei He, Xiaoxiao Ma, Guoli Liu, Xiangbing Bian, Song Wang, Sisi Li, Jianxun Qu, Caohui Duan, Xin Lou   +9 more
wiley   +1 more source

IDH Genotyping and Glioma Prognosis Research Based on an Interpretable Transformer Learning Framework

CAAI Transactions on Intelligence Technology, EarlyView.
ABSTRACT Accurate genotyping and prognosis of glioma patients present significant clinical challenges, often dependent on subjective judgement and insufficient scientific evidence. This study aims to develop a robust, noninvasive preoperative multi‐modal MRI‐based transformer learning model to predict IDH genotyping and glioma prognosis.
Xuan Yu, Yaping Wu, Yan Bai, Nan Meng, Shuting Jin, Qingxia Wu, Lijuan Chen, Ningli Wang, Xiaosheng Song, Guofeng Shen, Meiyun Wang   +10 more
wiley   +1 more source

Evidence for an arginine residue at the coenzyme-binding site of Escherichia coli isocitrate dehydrogenase [PDF]

, 1989
J S McKee, Hugh G. Nimmo
openalex   +1 more source