Results 111 to 120 of about 14,848 (191)

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

open access: yesExperimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu   +4 more
wiley   +1 more source

In Vivo Quantification of Creatine Kinase Kinetics in Mouse Brain Using 31P‐MRS at 7 T

open access: yesNMR in Biomedicine, Volume 38, Issue 6, June 2025.
We demonstrate the feasibility of using 31P‐MRS to quantify creatine kinase activity in the mouse brain on preclinical 7‐T scanners. A 20% drop in respiration increased the apparent forward rate constant by 36%, likely due to altered pH and mitochondrial ATP production.
Mohamed Tachrount   +3 more
wiley   +1 more source

Isoenzymatic polymorphisms in urban populations of Drosophila willistoni Polimorfísmo isoenzímático en poblaciones urbanas de Drosophila willistoni

open access: yesRevista Chilena de Historia Natural, 2001
Natural populations of Drosophila willistoni collected both in urban sites and in the wild, as control, were analysed with respect to their isoenzyme polymorphisms in six loci of enzyme systems, through horizontal electrophoresis.
CARMEN C. R. SAAVEDRA   +3 more
doaj  

LACTATE DEHYDROGENASE ISOENZYMES IN TRANSECTED NERVES* [PDF]

open access: green, 1964
Reinhard L. Friede, Mechthilde Knoller
openalex   +1 more source

Amino Acid Stress Response Genes Contribute to a 25‐Fold Increased Risk of L‐Asparaginase–Induced Hypersensitivity

open access: yesPediatric Blood &Cancer, Volume 72, Issue 6, June 2025.
ABSTRACT Background L‐asparaginase is essential in treating pediatric acute lymphoblastic leukemia (ALL) but is limited by hypersensitivity reactions in up to 70% of patients, leading to severe, dose‐limiting complications and compromised event‐free survival. Procedure This study conducted a genome‐wide association study (GWAS) in a discovery cohort of
Spencer J. Anderson   +10 more
wiley   +1 more source

Molecular docking‐guided in‐depth investigation of the biological activities and phytochemical and mineral profiles of endemic Phlomis capitata

open access: yesJournal of the Science of Food and Agriculture, Volume 105, Issue 7, Page 3760-3775, May 2025.
Abstract BACKGROUND Phlomis capitata is an endemic species of flowering aromatic and medicinal plant in the family Lamiaceae, native to regions of the Mediterranean and nearby areas. Understanding the chemical compounds present in P. capitata can reveal potential medicinal properties.
Ebubekir İzol
wiley   +1 more source

Volatile and Non‐Volatile Compounds in Retort‐Processed Green Beans Packaged in Metallic Cans Coated With Corrosion Resistant Polymers

open access: yesPackaging Technology and Science, Volume 38, Issue 5, Page 425-441, May 2025.
This study investigated the influence of retorted green beans, chlorophyll and methyl cysteine on the stability of polyethylene erephthalate laminate and polyester coatings for metallic food cans. After storing the sealed cans at 40°C for up to 90 days, the coatings and the can contents were evaluated for the presence of migrating volatile and non ...
Elliot Dhuey   +6 more
wiley   +1 more source

Highly Brominated Quinolines: Synthesis, Characterization, and Investigation of Anticancer Activities Supported by Molecular Dynamics

open access: yesChemical Biology &Drug Design, Volume 105, Issue 5, May 2025.
Further bromination of methoxy quinoline furnished novel polyfunctionalized quinoline derivatives. Additionally, nitration of dibromoquinoline gave 5‐nitrated quinoline. Their significant anticancer activities were determined and also supported by in silico studies.
Osman Çakmak   +5 more
wiley   +1 more source

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