Results 111 to 120 of about 29,683 (224)

Unveiling the Diagnostic Value and Potential Therapeutic Targets of Phenylalanine Metabolism in Pancreatic Cancer via Integrated Multi‐Omics and Machine Learning

The FASEB Journal, Volume 40, Issue 18, 30 September 2026.
MR identified phenylalanine as a causal PC risk factor (OR 1.18). A 5‐gene RF model (AUC 0.955) highlighted SLC6A14 as the top biomarker. Single‐cell analysis revealed epithelial–immune crosstalk. Molecular docking identified genistein (−9.1 kcal/mol) as a lead SLC6A14‐targeting compound.
Xing Liu, Yibin Li, Fangfang Qin, Jianghong Ou   +3 more
wiley   +1 more source

Structure‐Guided Optimization of PDE9A Inhibitors Tackling Neuroinflammation: A Combined Computational and In Vitro Study

ChemMedChem, Volume 21, Issue 17, 14 September 2026.
Computational studies allowed the identification of a PDE9A inhibitor. A novel HPLC‐based assay was developed and optimized to measure enzyme function to assess PDE9A inhibition. Furthermore, in vitro tests supported the activity of the compound against neuroinflammation. Oxidative stress and inflammation are key players in central nervous system (CNS)
Giovanni Ribaudo, Elisa Landucci, Margrate Anyanwu, Costanza Mazzantini, Matteo Giannangeli, Stefano Rosa, Francesca Mainolfi, Maura Calvani, Maurizio Memo, Domenico E. Pellegrini‐Giampietro, Alessandra Gianoncelli   +10 more
wiley   +1 more source

Microwave‐Assisted Subcritical Water Extraction Method for the Optimized Isolation of Cellulose From Residual Soybean Hulls

ChemSusChem, Volume 19, Issue 17, 14 September 2026.
Almost pure cellulose was extracted from soybean hulls by microwave‐assisted alkaline treatment (MW‐NaOH) and characterized. The microwave‐assisted subcritical water extraction (MASWE) of waste biomass falls within the circular economy approach, promotes sustainability, and reduces both treatment times and the use of harsh chemicals.
Monica Rigoletto, Maria Laura Tummino, Elisa Natali, Chiara Angileri, Giorgio Grillo, Silvia Tabasso, Veronica Bortolotto, Claudia L. Bianchi, Giancarlo Cravotto, Enzo Laurenti   +9 more
wiley   +1 more source

Effects of extracted soy isoflavones alone on blood total and LDL cholesterol: Meta-analysis of randomized controlled trials

, 2008
Kyoko Taku1, Keizo Umegaki1, Yoshiko Ishimi2, Shaw Watanabe31Information Center, National Institute of Health and Nutrition, Tokyo, Japan; 2Nutritional Epidemiology Program, National Institute of Health and Nutrition, Tokyo, Japan; 3Nutritional Education
Keizo Umegaki, Kyoko Taku, Shaw Watanabe, Yoshiko Ishimi   +3 more
core  

HPLC analysis of selected isoflavones [PDF]

, 2020
Charles University Faculty of Pharmacy in Hradec Králové Department of Biophysics and Physical Chemistry Author: Lidmila Nováková Supervisor: Ing. Vladimír Kubíček, CSc. Title of thesis: HPLC analysis of selected isoflavones The diploma thesis deals with
Nováková, Lidmila
core  

The effect of various acidic solutions on the concentration of genistein in tempeh [PDF]

, 2000
Plan BTempeh is a fermented soyfood that contains a higher level of genistein in comparison to nonfermented soyfoods, such as tofu and soymilk. Control tempehs prepared in this research contained concentrations of genistein seven times greater (49.70 ...
Garlock, Lori A.
core  

Soy protein with and without isoflavones fails to substantially increase postprandial antioxidant capacity.

, 2012
[[abstract]]Five methods for the assessment of antioxidant capacity [whole plasma conjugated diene formation, low-density lipoprotein oxidation susceptibility, ferric-reducing ability of plasma, oxygen radical absorbance capacity and perchloric-acid ...
張竣維;Hebron, C.Chang
core  

Prenylated isoflavonoids from soya and licorice : analysis, induction and in vitro estrogenicity [PDF]

, 2011
Prenylatedisoflavonoids are found in large amountsin soya bean (Glycine max) germinated under stress and in licorice (Glycyrrhiza glabra). Prenylation of isoflavonoids has been associated with modification of theirestrogenic activity.
Simons, R.
core  

Microencapsulation techniques and encapsulating materials influenced the shelf life and digestion release of vitamin E and isoflavones in soymilk powder

Scientific Reports
Soymilk, due to its high-quality protein and isoflavones content, is widely consumed worldwide. Unfortunately, soymilk lacks the powerful antioxidant vitamin E. Encapsulation of vitamin E and isoflavones in soymilk powder is advantageous for malnourished
Pakkawat Detchewa, Chutima Aphibanthammakit, Anuchita Moongngarm, Sylvie Avallone, Patcharee Prasajak, Chadaporn Boonpan, Varathip Ruangdath, Wichien Sriwichai   +7 more
doaj   +1 more source

Development of an analytical method for the quantification of isoflavones in legumes by SPE-UHPLC-MS/MS.

, 2014
Legumes include lentils (Lens culinaris L.), beans (Phaseolus vulgaris L.), chickpeas (Cicer arietinum L.), fava beans (Vicia faba or Faba vulgaris), soy beans (Glycine max) and others.
Ricciutelli M., Vila-Donat P., Cortese M., Torregiani E., Maggi F., Sagratini G. and Vittori S., Caprioli G.   +6 more
core   +1 more source