Rapid identification of isometamidium-resistant stocks of Trypanosoma b. brucei by PCR–RFLP
Analyses were made on the adenosine transporter-1 gene in Trypanosoma brucei (TbAT1), encoding a P2-like nucleoside transporter, from T. brucei brucei field stocks to investigate a possible link between the presence of mutations in this gene and isometamidium resistance.
Afework, Yohannes +5 more
openaire +3 more sources
The aim of this study was to assess trypanosome infection effects on the work performance of trypanotolerant cattle in the subhumid zone of Senegal. The study was conducted on Ndama cattle with a mean live weight of 288 kg and a mean age of six years ...
M. T. Seck +4 more
doaj +1 more source
Decrease in survival and fecundity of Glossina palpalis gambiensis vanderplank 1949 (Diptera : Glossinidae) fed on cattle treated with single doses of ivermectin [PDF]
Background: Human and Animal Trypanosomes are major problems for the socio-economic growth of developing countries like Burkina Faso. Ivermectin is currently used to treat humans in mass drug administration programs in Africa, and is also commonly used ...
Bengaly, Z. +4 more
core +1 more source
Variabilité génétique de Trypanosoma congolense, agent de la trypanosomose animale : implications taxonomiques et épidémiologiques [PDF]
#Trypanosoma congolense$ est une espèce de protozoaire parasite, qui est un des responsables majeurs de la trypanosome animale sévissant en Afrique. Il fait partie du sous-genre #Nannonomas$, de la famille des #Trypanosomatidae$.
Sidibé, Issa
core
Prothidium and isometamidium as drug against Trypanosoma brucei canine trypanosomiasis [PDF]
Le Prothidium et l'Isométamidium ont été utilisés dans le traitement de plusieurs cas de trypanosomiase expérimentale du chien à Trypanosoma brucei. Le Prothidium est administré à raison de 2 mg/kg de la solution à 2 p.100 et l'Isométamidium 1 mg/kg de ...
Touré, Saydil
core
Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from northwestern Uganda following melarsoprol withdrawal [PDF]
Human African trypanosomiasis (HAT) manifests as a chronic infection caused by <i>Trypanosoma brucei gambiense</i>, or as a more acute form due to <i>T. b. rhodesiense</i>.
Barrett, M.P. +5 more
core +3 more sources
Epidemiology, Diagnosis And Chemoprophylaxis Of Trypanosoma Evansi Infection In Dairy Cattle [PDF]
Trypanosomiasis caused by Trypanosoma evansi is considered to be one of the diseases of economic importance affecting dairy cattle in Malaysia. An investigation into the epidemiology, diagnosis and chemoprophylaxis of T.
Cheah, Tong Soon
core
The monomorphic, non-cyclic, extracellular haemoprotozoan parasite, Trypanosoma evansi leads to Surra disease in domesticated animals. Currently, diminazene aceturate (DA) and isometamidium chloride (ISM) are the most used chemotherapeutic agents for ...
SNEHIL GUPTA +6 more
doaj +1 more source
Background Diminazene diaceturate (DA) and isometamidium chloride hydrochloride (ISM) are with homidium bromide, the main molecules used to treat African Animal Trypanosomosis (AAT).
Zakaria Bengaly +11 more
doaj +1 more source
Transport of isometamidium (Samorin) by drug-resistant and drug-sensitiveTrypanosoma congolense
The uptake kinetics of a14C-labelled trypanocidal compound isometamidium chloride (SamorinR, RMB Animal Health Ltd, UK) was measured in drug-resistant and drug-sensitiveTrypanosoma congolense. It was established that drug uptake was significantly more rapid and quantitatively greater in drug-sensitive parasites.
I A, Sutherland, A, Mounsey, P H, Holmes
openaire +2 more sources

