Transport proteins determine drug sensitivity and resistance in a protozoan parasite, Trypanosoma brucei [PDF]
Drug resistance in pathogenic protozoa is very often caused by changes to the ‘transportome’ of the parasites. In Trypanosoma brucei, several transporters have been implicated in uptake of the main classes of drugs, diamidines and melaminophenyl ...
De Koning, Harry P. +2 more
core +1 more source
Evolution of bovine Trypanosomosis by Trypanosoma vivax in Formosa (Argentina). Years 2007-2012 and its potential spread in the country [PDF]
En base al diagnóstico parasitológico para para tripanosomas de bovinos, se describe la evolución de la onda epizoótica del T. vivax iniciada en Argentina hacia finales del año 2006.
Giménez, Juana Noemí +3 more
core +1 more source
Determination of Residual Isometamidium in Cattle Tissues and Milk by HPLC
A determination method for the antitripanosomal agent, isometamidium (IMD) in cattle muscle, liver, fat and milk has been developed by using HPLC. The drug was extracted from a sample with acetonitrile-0.25mol/L ammonium formate methanol solution, and purified by liquid-liquid partition with ethyl acetate and water, followed by extraction of the water ...
Kazunari KONDO +4 more
openaire +2 more sources
Subverting lysosomal function in Trypanosoma brucei. [PDF]
In this issue of Microbial Cell, Koh and colleagues present data highlighting the utility of the lysosomotropic compound L-leucyl-L-leucyl methyl ester (LeuLeu-OMe) as an anti-Trypanosoma brucei agent, adding to the range of compounds that either ...
Alsford, Sam
core +3 more sources
Developing a progressive control pathway for African animal trypanosomosis [PDF]
Progressive control pathways (PCPs) are stepwise approaches for the reduction, elimination, and eradication of human and animal diseases. They provide systematic frameworks for planning and evaluating interventions.
Argilés-Herrero, Rafael +8 more
core +1 more source
Trypanosoma equiperdum in the horse : a neglected threat? [PDF]
Dourine is a contagious disease caused by Trypanosoma equiperdum that is transmitted directly from animal to animal during coitus. Dourine is known as an important disease in many countries, and it threatens equidae worldwide.
Ahmed, Y +6 more
core
Review of livestock pathology in the central African region: epidemiological considerations and control strategies [PDF]
International audienceDisease has consistently featured among the major constraints of livestock production in the central African region, causing important economic losses.
Daniel Achukwi, Mbunkah +1 more
core +1 more source
Clinical and therapeutic aspects of an outbreak of canine trypanosomiasis
Trypanosomiasis caused by Trypanosoma evansi can seriously affect both domestic and wild animals. This article reports on an outbreak of canine trypanosomiasis on a farm in the Pantanal region of Brazil.
Jessica Teles Echeverria +9 more
doaj +1 more source
Melarsomine hydrochloride can cure Trypanosoma evansi infection in camels at a dose of 0·25 mg/kg, but at that dose relapses occur in cattle. In our study, the efficacy of an intramuscular injection of melarsomine hydrochloride at 0·5 mg/kg was assessed ...
Desquesnes, Marc +5 more
core +1 more source
Variation of sensitivity of Trypanosoma evansi isolates from Isiolo and Marsabit counties of Kenya to locally available trypanocidal drugs. [PDF]
Mdachi RE +10 more
europepmc +1 more source

