Results 71 to 80 of about 475 (151)
Heliyon, 2018 The current study was undertaken from December 2015 to May 2016 with the aim of determining and comparing the pathogenicity and response to diminazene aceturate (DA) and isometamidium chloride (ISM) treatment in experimentally infected mice with ...
Muluken Yayeh +7 more
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Time-dose response of Trypanosoma congolense bloodstream forms to diminazene and isometamidium
Veterinary Parasitology, 1994 Trypanosoma congolense bloodstream forms were propagated in vitro axenically in a simplified cultivation medium at 34 degrees C. Viability of a drug-sensitive and a drug-resistant clone were examined for 10 days following exposure to 0.1, 1.0 and 10.0 micrograms ml-1 of diminazene aceturate and 0.1, 1.0 and 10.0 ng ml-1 of isometamidium chloride for ...
Kaminsky, R., Chuma, F., Wasike, R.P.N.
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Rapid identification of isometamidium-resistant stocks of Trypanosoma b. brucei by PCR–RFLP
Parasitology Research, 2006 Analyses were made on the adenosine transporter-1 gene in Trypanosoma brucei (TbAT1), encoding a P2-like nucleoside transporter, from T. brucei brucei field stocks to investigate a possible link between the presence of mutations in this gene and isometamidium resistance.
Afework, Yohannes +5 more
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Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2002 The aim of this study was to assess trypanosome infection effects on the work performance of trypanotolerant cattle in the subhumid zone of Senegal. The study was conducted on Ndama cattle with a mean live weight of 288 kg and a mean age of six years ...
M. T. Seck +4 more
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Transport of isometamidium (Samorin) by drug-resistant and drug-sensitiveTrypanosoma congolense
Parasitology, 1992 The uptake kinetics of a14C-labelled trypanocidal compound isometamidium chloride (SamorinR, RMB Animal Health Ltd, UK) was measured in drug-resistant and drug-sensitiveTrypanosoma congolense. It was established that drug uptake was significantly more rapid and quantitatively greater in drug-sensitive parasites.
I A, Sutherland, A, Mounsey, P H, Holmes
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Indian Journal of Animal SciencesThe monomorphic, non-cyclic, extracellular haemoprotozoan parasite, Trypanosoma evansi leads to Surra disease in domesticated animals. Currently, diminazene aceturate (DA) and isometamidium chloride (ISM) are the most used chemotherapeutic agents for ...
SNEHIL GUPTA +6 more
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BMC Veterinary Research, 2018 Background Diminazene diaceturate (DA) and isometamidium chloride hydrochloride (ISM) are with homidium bromide, the main molecules used to treat African Animal Trypanosomosis (AAT).
Zakaria Bengaly +11 more
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Determination of Residual Isometamidium in Cattle Tissues and Milk by HPLC
Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi), 1999 A determination method for the antitripanosomal agent, isometamidium (IMD) in cattle muscle, liver, fat and milk has been developed by using HPLC. The drug was extracted from a sample with acetonitrile-0.25mol/L ammonium formate methanol solution, and purified by liquid-liquid partition with ethyl acetate and water, followed by extraction of the water ...
Kazunari KONDO +4 more
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Clinical and therapeutic aspects of an outbreak of canine trypanosomiasis
Revista Brasileira de Parasitologia VeterináriaTrypanosomiasis caused by Trypanosoma evansi can seriously affect both domestic and wild animals. This article reports on an outbreak of canine trypanosomiasis on a farm in the Pantanal region of Brazil.
Jessica Teles Echeverria +9 more
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New Trypanosoma evansi Type B Isolates from Ethiopian Dromedary Camels.
PLoS Neglected Tropical Diseases, 2016 BackgroundTrypanosoma (T.) evansi is a dyskinetoplastic variant of T. brucei that has gained the ability to be transmitted by all sorts of biting flies. T.
Hadush Birhanu +4 more
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