Results 121 to 130 of about 95,782 (307)

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

Lupus Vulgaris in a Maltese patient [PDF]

open access: yes, 2004
Introduction The incidence of cutaneous tuberculosis (TB) in the developed world has fallen, in parallel with the decline of other forms of TB. Nevertheless cases still occur and their diagnosis may be difficult.
Boffa, Michael J.   +2 more
core  

Linezolid-containing regimens for the treatment of drug-resistant tuberculosis in South African children.

open access: yes, 2012
BACKGROUND: Treatment options for drug-resistant tuberculosis (DR-TB) are limited. Linezolid has been successfully used to treat DR-TB in adults, but there are few case reports of its use in children for TB.
Hallbauer, UM   +4 more
core   +1 more source

Multiple Bilateral Erythematous and Suppurative Cutaneous Nodules in a 40‐Year‐Old Indian Female

open access: yes
JEADV Clinical Practice, EarlyView.
Aditi Anand   +2 more
wiley   +1 more source

Challenges and Considerations in Manipulating Oral Dosage Forms in Paediatric Healthcare Settings: A Narrative Review

open access: yesActa Paediatrica, EarlyView.
A substantial proportion of oral drug administrations in children require manipulation due to the lack of age‐appropriate formulations. Common methods such as splitting, crushing, and dispersing tablets in fluids can compromise dose accuracy because of e.g., drug solubility.
M. Paulsson   +5 more
wiley   +1 more source

Efficacy, safety, and pharmacokinetics of isoniazid affected by NAT2 polymorphisms in patients with tuberculosis: A systematic review

open access: yesClinical and Translational Science
N‐acetyltransferase 2 (NAT2) genetic polymorphisms might alter isoniazid metabolism leading to toxicity. We reviewed the impact of NAT2 genotype status on the pharmacokinetics, efficacy, and safety of isoniazid, a treatment for tuberculosis (TB).
Thanakorn Surarak   +3 more
doaj   +1 more source

Dasatinib overcomes AML cells resistant to BCL2 inhibition by degrading MCL1

open access: yesBritish Journal of Haematology, EarlyView.
Summary Acute myeloid leukaemia (AML) is a severe disease occurring mainly in the elderly population. Venetoclax (VEN) combined with azacitidine has changed the paradigm of treatment of AML. Nevertheless, approximately 30% of patients are primary refractory to VEN (VEN‐R), with no current therapeutic option.
Sylvain Garciaz   +12 more
wiley   +1 more source

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