Results 131 to 140 of about 95,782 (307)
Passive Versus Active Tuberculosis Case Finding and Isoniazid Preventive Therapy Among Household Contacts in a Rural District of Malawi. [PDF]
SETTING: Thyolo district, rural Malawi. OBJECTIVES: To compare passive with active case finding among household contacts of smear-positive pulmonary tuberculosis (TB) patients for 1) TB case detection and 2) the proportion of child contacts aged under 6 ...
Bakali, E+6 more
core +1 more source
Through the ‘4As’: Awareness, Access, Advocacy, and Alliance, the Greater Bay Area will continue to leverage its unique advantages to confront ongoing challenges such as diagnostic delays and lack of access to diagnosis and hereditary angioedema (HAE)‐specific medications.
Philip H. Li+22 more
wiley +1 more source
The Diverse Genetic Landscape of Hearing Impairment in South African Families
South African Families with Nonsyndromic (N = 24) and Syndromic Hearing Impairment (N = 21) with ≥ 2 affected members were analyzed. The underlying etiology was uncovered using exome and Sanger sequencing for 31 of these families. ABSTRACT To elucidate the genetic etiology of hearing impairment (HI) in South Africa, 45 nonsyndromic HI (NSHI) and ...
Thashi Bharadwaj+10 more
wiley +1 more source
Catalase Activity and Isoniazid Sensitivity of Tubercle Bacilli [PDF]
A. Beck
openalex +1 more source
Synaptic inhibitory dynamics drive benzodiazepine response in pediatric status epilepticus
Abstract Objective Pediatric status epilepticus (SE) is a medical emergency associated with significant morbidity. Benzodiazepines (BZPs) are the current first‐line treatment, but do not work in more than one third of children presenting with SE. Animal studies have shown that SE can cause changes in synaptic inhibition signaling that can ultimately ...
Tommaso Fedele+5 more
wiley +1 more source
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof of principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalographic response (PPR) as a surrogate of seizures, is currently the only human model that allows POP trials of investigational compounds after a ...
Wolfgang Löscher+1 more
wiley +1 more source
Mutations in 1700 Bp Fragment of Rpob Gene of Multi-drug Resistant Mycobacterium Tuberculosis Isolate [PDF]
This research aimed to amplify a 1700 bp fragment of rpoB gene of multidrug resistance M. tuberculosis (MDR-TB) isolate and determine types of mutation beyond the core region (hot-spot region).
Junitha, I. K. (I)+3 more
core
Summary Two foals were being treated with a combination of oral doxycycline and rifampin for presumed Rhodococcus equi infections. After 3–4 weeks of antimicrobial administration, both foals presented with icterus and nonspecific clinical signs, including lethargy and inappetence.
A. Murdock+7 more
wiley +1 more source