The Lancet Microbe, 2020 Summary: Background: Clinical studies suggest that isoniazid contributes rapid bacterial killing during the initial 2 days of tuberculosis treatment, but that the activity of isoniazid declines substantially after day 3 of treatment.
Andreas Diacon, ProfPhD +11 more
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Potential economic viability of two proposed rifapentine-based regimens for treatment of latent tuberculosis infection. [PDF]
PLoS ONE, 2011 Rifapentine-based regimens for treating latent tuberculosis infection (LTBI) are being considered for future clinical trials, but even if they prove effective, high drug costs may limit their economic viability.To inform clinical trial design by ...
David P Holland +3 more
doaj +1 more source
Leptomeningitis in a person with radiologically isolated syndrome and latent tuberculosis. A case report with implications for clinical research [PDF]
, 2018 A 39-year-old man, followed with serial MRI of CNS for a radiologically isolate syndrome (RIS, a recently described condition considered a subclinical form of MS), was hospitalized for the occurrence of a leptomeningitis. Routine blood tests and contrast
Bozzao, Alessandro +8 more
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EFFECT OF PARACETAMOL ON THE RENAL CLEARANCE AND URINARY EXCRETION OF ISONIAZID IN GOATS [PDF]
Pakistan Veterinary Journal, 2009 Effect of paracetamol on renal clearance and urinary excretion of isoniazid was investigated in eight healthy adult female goats in two phases. In the first phase, each goat was administered isoniazid orally as a single dose at the rate of 10 mg/kg body ...
T. HUSSAIN, I. JAVED, F. H. KHAN, F. MUHAMMAD, B. ASLAM, S. AHMAD1, I. U. JAN2, A. BASIT AND U. TAHIR3
doaj
Quantifying Isoniazid Levels in Small Hair Samples: A Novel Method for Assessing Adherence during the Treatment of Latent and Active Tuberculosis. [PDF]
, 2016 BackgroundTuberculosis (TB) is the leading cause of death from an infectious pathogen worldwide and the most prevalent opportunistic infection in people living with HIV.
Bacchetti, Peter +6 more
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Туберкулез и болезни лёгких, 2017 Goal of the study: to investigate the impact of isoniazid combined with silver nanoparticles on the isoniazid resistant strains of tuberculous mycobacteria and the course of experimental of tuberculosis caused by the above strains.Materials and ...
A. V. Zаkhаrov +3 more
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Anti-Tubercular Drug-Induced Liver Injury: Current Understanding and Emerging Directions. [PDF]
JGH OpenABSTRACT Most common adverse effect causing cessation of anti‐tubercular treatment (ATT) is drug‐induced liver injury (DILI) which is unpredictable due to its idiosyncratic nature. ATT is the most common cause of DILI and drug‐induced acute liver failure (ALF) in South East Asia.
Prasad S, Narang H, Kedia S, Ahuja V.
europepmc +2 more sources
Research Progress of isoniazid electrochemical sensors
Electrochemistry CommunicationsThis paper reviews the research progress of isoniazid electrochemical sensors in recent years. As an important anti-tuberculosis drug, the rapid and sensitive detection of isoniazid is of great significance for clinical treatment and drug quality control.
Huanyu Che +5 more
doaj +1 more source
Saudi Pharmaceutical Journal, 2020 Isoniazid is the most commonly used drug for treatment of tuberculosis, and is administered individually or in combination with other drugs as standard first line therapy.
Faisal Imam +5 more
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Effect of Prednisolone and Rifampin on Isoniazid Metabolism in Slow and Rapid Inactivators of Isoniazid [PDF]
, 1980 The effect of prednisolone and rifampin, alone and in combination, on the biodisposition of isoniazid in slow and rapid inactivators of isoniazid was investigated.
Kailasam, S +4 more
core +2 more sources