Results 81 to 90 of about 97,287 (310)

Inhibitory Effect of Antituberculosis Drugs on Human Cytochrome P450-Mediated Activities

Journal of Pharmacological Sciences, 2004
The potential for drug-drug interactions mediated by the inhibition of cytochrome P-450 (CYP) were concerned during antituberculosis therapy. However, the information regarding human CYP inhibition by antituberculosis drugs is limited to isoniazid.
Yuki Nishimura, Norimitsu Kurata, Eriko Sakurai, Hajime Yasuhara   +3 more
doaj   +1 more source

Advancing Energy and Indoor Environmental Quality Through Integrated Co‐Simulation and Multi‐Objective Optimisation for SARS‐CoV‐2 Risk Mitigation: A UK Case Study

Energy Science &Engineering, EarlyView.
ABSTRACT In today's modern world, people spend most of their time indoors, making indoor air quality (IAQ) a critical concern, particularly in educational buildings, where densely occupied classrooms demand clean and healthy environments. This study enhances the IAQ of an existing college building in West London by aiming to reduce carbon dioxide (CO2)
Atefeh Abbaspour, Ali Bahadori‐Jahromi, Alan Janbey, Hooman Tahayori   +3 more
wiley   +1 more source

Isoniazid potentiates tigecycline to kill methicillin-resistant Staphylococcus aureus

Emerging Microbes and Infections
Therapeutic option for treating methicillin-resistant Staphylococcus aureus (MRSA) infection is urgently required since its resistance to a broad spectrum of currently available antibiotics.
Xuan-wei Chen, Hao-qing Chen, Jia-han Wu, Zhi-han Wang, Yu-Qing Zhou, Si-qi Tian, Bo Peng   +6 more
doaj   +1 more source

Isoniazid use, effectiveness, and safety for treatment of latent tuberculosis infection: a systematic review [PDF]

Revista da Sociedade Brasileira de Medicina Tropical
Background: The treatment strategy for latent tuberculosis infection is to reduce the number of tuberculosis cases and consequently reduce the transmission of pathogenic bacteria. This study aimed to determine the safety, effectiveness, and adherence of
Bárbara Manuella Cardoso Sodré-Alves, Melina Mafra Toledo, Ivan Ricardo Zimmermann, Wildo Navegantes de Araújo, Noemia Urruth Leão Tavares   +4 more
doaj   +1 more source

Benefits of Therapeutic Drug Monitoring of First Line Antituberculosis Drugs

Acta Medica Martiniana, 2020
Tuberculosis is an airborne infectious disease that remains a huge global health-related issue nowadays. Despite constant approvals of newly developed drugs, the use of first-line antituberculosis medicines seems reasonable in drug-susceptible ...
Prso K, Zidekova N, Dohal M, Porvaznik I, Prso M, Kertys M, Mokry J   +6 more
doaj   +1 more source

Renoprotective Effect of Coix lachryma‐jobi L. Seed Polysaccharides in Adenine‐Induced Chronic Renal Failure by Blocking Gut Urea Metabolism

Food Frontiers, EarlyView.
ABSTRACT Dietary soluble fiber may alleviate renal damage in chronic kidney disease (CKD) by promoting intestinal urea excretion, though the underlying mechanisms remain unclear. This study investigated the digestion, fermentation, and renoprotective effects of Coix lachryma‐jobi L.
Hongmei Yin, Wanjun Liao, Yilian Huang, Qiang Hong, Na Zhang, Xiaodan Shi, Zongcai Tu, Hui Wang, Zuohua Xie, Tao Yuan   +9 more
wiley   +1 more source

Factors associated with isoniazid resistant tuberculosis among human immunodeficiency virus positive patients in Swaziland: a case-control study

BMC Infectious Diseases, 2019
Background Isoniazid resistant tuberculosis is the most prevalent type of resistance in Swaziland and over two-thirds of the isoniazid resistant tuberculosis patients are tuberculosis and human immunodeficiency virus co-infected.
Nonhlanhla Christinah Dlamini, Dar-Der Ji, Li-Yin Chien   +2 more
doaj   +1 more source

A Multinational Analysis of Mutations and Heterogeneity in PZase, RpsA, and PanD Associated with Pyrazinamide Resistance in M/XDR Mycobacterium tuberculosis. [PDF]

, 2017
Pyrazinamide (PZA) is an important first-line drug in all existing and new tuberculosis (TB) treatment regimens. PZA-resistance in M. tuberculosis is increasing, especially among M/XDR cases.
Catanzaro, A, Catanzaro, D, Fink, L, Jackson, RL, Pettigrove, M, Ramirez-Busby, SM, Rodwell, TC, Valafar, F   +7 more
core   +1 more source

Impact of isoniazid monoresistance on overall and vulnerable patient populations in Taiwan

Emerging Microbes and Infections
Isoniazid is an early bactericidal anti-tuberculosis (TB) agent and isoniazid mono-resistance TB is the most prevalent drug-resistant TB worldwide. Concerns exist regarding whether resistance to isoniazid would lead to delayed culture conversion and ...
Meng-Rui Lee, Li-Ta Keng, Ming-Chia Lee, Jin-Hua Chen, Chih-Hsin Lee, Jann-Yuan Wang   +5 more
doaj   +1 more source

Isoniazid-Induced Acute Psychosis in a Patient with Pleural Tuberculosis

Case Reports in Psychiatry, 2019
Tuberculosis is one of the top 10 causes of death and the leading cause from a single infectious agent (above HIV/AIDS). Isoniazid is highly bactericidal against replicating tubercle bacilli and is a component of all antituberculous chemotherapeutic ...
Joana Gomes, Diana Durães, André Sousa, Hugo Afonso   +3 more
doaj   +1 more source