We studied the presence of mutations in the whole katG gene and specific regions of the oxyR-ahpC and mabA-inhA regulatory region in 61 Mycobacterium tuberculosis isoniazid-resistant isolates.
Manterola, Jose M. +8 more
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Rapid detection of non-rifampicin resistant drug-resistant tuberculosis using Xpert MTB/XDR testing: Findings from a multisite drug-resistant tuberculosis case detection surge in Zambia. [PDF]
Mwaba PB +12 more
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Targeted Nanopore Sequencing for Molecular Characterization of First-Line Drug Resistance and Treatment Outcomes Among Patients in the Republic of Congo. [PDF]
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Two Case Reports of Drug-Resistant Tuberculous Pleurisy in Children: Thoracoscopic Pleural Biopsy and PCR-Based Drug-Resistance Testing. [PDF]
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Global and Regional Patterns of Drug Resistance and Treatment Regimens in Spinal Tuberculosis: A Systematic Review and Meta-Analysis. [PDF]
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Isoniazid Preventive Therapy in Areas of High Isoniazid Resistance
Archives of Internal Medicine, 1995One can examine any potential patient population with decision analysis as long as relevant data are available in the literature. To our knowledge, TB case-fatality rates have not been stratified according to disease severity at the time the patient sought medical attention or to the quality of medical care received.
T R, Sterling, W T, Brehm, T R, Frieden
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Isoniazid-Resistant Cavitary Tuberculosis in a Physician Following Isoniazid Prophylaxis
Infection Control & Hospital Epidemiology, 2002Abstract Single-drug prophylaxis is recommended after tuberculin skin test conversion, but not when there is active disease on chest radiograph because resistance develops frequently. Isoniazid-resistant tuberculosis developed in a physician receiving prophylaxis despite “faint left upper lobe soft tissue density” on chest radiograph.
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