Results 181 to 190 of about 2,381,535 (223)

ISONIAZID‐RESISTANT TUBERCULOUS SUPERINFECTION

Journal of the American Geriatrics Society, 1970
A bstract : Isoniazid resistance developed after one to eleven years of clinical and bacteriologic quiescence in 13 once‐responsive tuberculous patients. A study of the case material disclosed that all but one of the patients
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Isoniazid resistance in patients with pulmonary tuberculosis treated on isoniazid alone

Tubercle, 1954
Summary o (1) The results are given of a detailed study of 18 cases of pulmonary tuberculosis treated with isoniazid alone. (2) Sputum conversion occurred in 8 of the 18 patients by the 51st day. 5 later reverted to positive. In 2 of these the organisms isolated were sensitive to the drug, in the other 3 resistant.
A T, WALLACE, S M, STEWART, F A, TURNBULL, J W, CROFTON   +3 more
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Mechanisms of isoniazid resistance in Mycobacterium tuberculosis

Drug Resistance Updates, 1998
Isoniazid (INH) is a widely used front-line antituberculous agent with bacteriocidal activity at concentrations as low as 150 nM against Mycobacterium tuberculosis. INH is a prodrug and requires activation by an endogenous mycobacterial enzyme, the catalase-peroxidase KatG, before exerting toxic effects on cellular targets.
C E, Barry, R A, Slayden, K, Mdluli
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Isoniazid-Resistant Tuberculosis

JAMA, 1985
The choice of effective preventive treatment for persons exposed to Mycobacterium tuberculosis resistant to isoniazid is uncertain. Although no data document the efficacy of any drug other than isoniazid for preventive treatment of tuberculosis, rifampin, with or without ethambutol, has been used for prophylaxis in contacts of cases with known ...
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The fate of the patient with isoniazid-resistant tuberculosis

Journal of Chronic Diseases, 1962
Abstract This report is concerned with the fate of the patient who has chronic lung disease due to Mycobacterium tuberculosis that has become resistant to isoniazid. These patients for the most part have far-advanced, cavitary disease. Drug therapy often fails to achieve bacteriostasis.
H H, RUCHELMAN, I, CHOFNAS
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Isoniazid Preventive Therapy in Areas of High Isoniazid Resistance

Archives of Internal Medicine, 1996
The risk-benefit analysis of isoniazid preventive therapy in areas of high isoniazid resistance by Sterling et al 1 that appeared in the August 7/21, 1995, issue of theARCHIVESis welcome and badly needed. However, because of certain assumptions, I believe that the authors overstated the justification for giving isoniazid preventive therapy to many ...
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Haemin and Isoniazid Resistance of Mycobacterium tuberculosis

Journal of General Microbiology, 1955
In confirmation of Fisher's (1952, 1954a, b) results, haemin was found to act as an apparent growth factor for isoniazid-resistant strains of tubercle bacilli and also powerfully to antagonize the action of isoniazid on drug-sensitive organisms. In extension of Fisher's work, these effects of haemin were investigated with drug-sensitive and resistant ...
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Tuberculous meningitis and resistance to isoniazid

BMJ, 2010
Higher case fatality rate should prompt prudent use of antituberculous drugs In the linked study (doi:10.1136/bmj.c4451), Vinnard and colleagues assess whether initial resistance to isoniazid is associated with death during the treatment of tuberculous meningitis.1 Central nervous system tuberculosis accounts for about 1% of the estimated 9.4 million ...
B. Blomberg, N. Langeland
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Risk of tuberculosis among contacts of isoniazid-resistant and isoniazid-susceptible cases

The International Journal of Tuberculosis and Lung Disease, 2011
To compare the risk to household contacts of isoniazid (INH) susceptible and INH-resistant cases of tuberculosis (TB) in a rural community in South India.In all, 5562 contacts of INH-susceptible and 779 contacts of INH-resistant patients and 246,845 persons with no TB case in the home were followed for 15 years, with surveys every 2.5 years comprising ...
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Antibiotic Resistance in the Patient With Cancer: Escalating Challenges and Paths Forward

Ca-A Cancer Journal for Clinicians, 2021
Amila K Nanayakkara, David E Greenberg, Vance Fowler   +2 more
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