Results 51 to 60 of about 13,872 (224)

Isoprenoid alcohols utilization by malaria parasites

Frontiers in Chemistry, 2022
Plasmodium falciparum is the etiological agent of human malaria, one of the most widespread diseases in tropical and subtropical regions. Drug resistance is one of the biggest problems in controlling the disease, which leads to the need to discover new ...
Ignasi Bofill Verdaguer, Rodrigo A. C. Sussmann, Rodrigo A. C. Sussmann, Verônica Feijoli Santiago, Giuseppe Palmisano, Gabriel Cândido Moura, Juliana Tonini Mesquita, Lydia Fumiko Yamaguchi, Massuo Jorge Kato, Alejandro Miguel Katzin, Marcell Crispim   +10 more
doaj   +1 more source

Biosynthesis of isoprenoids [PDF]

European Journal of Biochemistry, 2004
In the nonmevalonate pathway of isoprenoid biosynthesis, the conversion of 2C‐methyl‐d‐erythritol 4‐phosphate into its cyclic diphosphate proceeds via nucleotidyl intermediates and is catalyzed by the products of the ispD, ispE and ispF genes. An open reading frame of Campylobacter jejuni with similarity to the ispD and ispF genes of Escherichia coli ...
Mads, Gabrielsen, Felix, Rohdich, Wolfgang, Eisenreich, Tobias, Gräwert, Stefan, Hecht, Adelbert, Bacher, William N, Hunter   +6 more
openaire   +2 more sources

Separation of trichothecene mycotoxins in a matrix of hemp (Cannabis sativa L.) seed, and quantification of deoxynivalenol in hemp grain infected with Fusarium graminearum

JSFA reports, EarlyView.
Abstract Background Fusarium graminearum, one of the causal agents of ear rot in maize and head blight of cereal grains, also infects hemp (Cannabis sativa L. containing a maximum of 0.3% tetrahydrocannabinol or THC). This fungal pathogen produces trichothecene mycotoxins when it infects maize and cereal grains, but little is known about its production
Isabelle A. Kagan, Magdalena Ricciardi, Henry S. Smith, Rachel R. Schendel, Robert Pearce, Nicole Gauthier   +5 more
wiley   +1 more source

Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori, Pedro Garcia Caparros, Antonella Castagna, Luisa Custódio, Valentina Lazazzara, Claus Krogh Madsen, Felicia Menicucci, Maria João Rodrigues, Katalin Solymosi, Jose Ramon Acosta Motos   +9 more
wiley   +1 more source

Phosphorylation of Metabolites Involved in Salvage Pathways for Isoprenoid Biosynthesis in Plants

, 2023
International audienceThe recycling of metabolic products is a major way to reduce the energy cost of de novo biosynthesis. The salvage pathways involved not only regain a metabolic product but also generate additional molecules that might serve specific
Andréa Hemmerlin, Hemmerlin, Andréa
core   +1 more source

Evolutionary flexibility and rigidity in the bacterial methylerythritol phosphate (MEP) pathway

Frontiers in Microbiology, 2023
Terpenoids are a diverse class of compounds with wide-ranging uses including as industrial solvents, pharmaceuticals, and fragrances. Efforts to produce terpenoids sustainably by engineering microbes for fermentation are ongoing, but industrial ...
Bailey Marshall, Bailey Marshall, Kaustubh Amritkar, Michael Wolfe, Michael Wolfe, Betül Kaçar, Robert Landick, Robert Landick, Robert Landick   +8 more
doaj   +1 more source

Differentiation of Plant and Animal‐Derived Cholesterol Using irm‐13C NMR and IRMS

Magnetic Resonance in Chemistry, EarlyView.
Determining and certifying the origin of ingredients, starting materials, and excipients used in manufactured goods like cosmetics and medicines can be difficult. In this report, we describe a robust approach for identifying the origin of cholesterol, a component of myriad consumer products using irm‐13C NMR and IRMS to differentiate plant versus ...
Anika M. Singh, Subir Chakraborty, Remington X. Poulin, R. Thomas Williamson   +3 more
wiley   +1 more source

Diversity of ABBA Prenyltransferases in Marine Streptomyces sp. CNQ-509: Promiscuous Enzymes for the Biosynthesis of Mixed Terpenoid Compounds.

PLoS ONE, 2015
Terpenoids are arguably the largest and most diverse family of natural products, featuring prominently in e.g. signalling, self-defence, UV-protection and electron transfer.
Franziska Leipoldt, Philipp Zeyhle, Andreas Kulik, Jörn Kalinowski, Lutz Heide, Leonard Kaysser   +5 more
doaj   +1 more source

Differential roles of Cassia tora 1-deoxy-D-xylulose-5-phosphate synthase and 1-deoxy-D-xylulose-5-phosphate reductoisomerase in trade-off between plant growth and drought tolerance

Frontiers in Plant Science, 2023
Due to global climate change, drought is emerging as a major threat to plant growth and agricultural productivity. Abscisic acid (ABA) has been implicated in plant drought tolerance, however, its retarding effects on plant growth cannot be ignored.
Chunyao Tian, Huige Quan, Ruiping Jiang, Qiaomu Zheng, Sipei Huang, Guodong Tan, Chaoyue Yan, Jiayu Zhou, Hai Liao   +8 more
doaj   +1 more source

Inhibition of the isoprenoid biosynthesis pathway; detection of intermediates by UPLC-MS/MS

, 2011
The isoprenoid biosynthesis pathway provides the cell with a variety of compounds which are involved in multiple cellular processes. Inhibition of this pathway with statins and bisphosphonates is widely applied in the treatment of hypercholesterolemia ...
Kulik, Willem, Waterham, Hans R., van Cruchten, Arno G., Willem Kulik, Linda Henneman, Henneman, Linda, Hans R. Waterham, Arno G. van Cruchten   +7 more
core   +1 more source