Results 31 to 40 of about 13,872 (224)
Metabolic Remodeling during Nitrogen Fixation in Zymomonas mobilis
mSystems, 2021 Zymomonas mobilis is an ethanologenic bacterium currently being developed for production of advanced biofuels. Recent studies have shown that Z. mobilis can fix dinitrogen gas (N2) as a sole nitrogen source. During N2 fixation, Z.
Julia I. Martien +7 more
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Journal of Lipid Research, 1999 Gene expression profiling is rapidly becoming a mainstay of functional genomic studies. However, there have been relatively few studies of how the data from expression profiles integrate with more classic approaches to examine gene expression. This study
Dago Dimster-Denk +10 more
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The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite
Nature Communications, 2021 Repeating fever is a hallmark of malaria. Here, a large-scale forward genetic screen in malaria-causing Plasmodium falciparum identifies genes associated with parasite tolerance to host fever, including apicoplast targeted isoprenoid biosynthesis—sharing
Min Zhang +14 more
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The suf iron-sulfur cluster synthesis pathway is required for apicoplast maintenance in malaria parasites. [PDF]
PLoS Pathogens, 2013 The apicoplast organelle of the malaria parasite Plasmodium falciparum contains metabolic pathways critical for liver-stage and blood-stage development.
Jolyn E Gisselberg +4 more
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Quantifying Isoprenoids in the Ergosterol Biosynthesis by Gas Chromatography–Mass Spectrometry
Journal of Fungi, 2023 The ergosterol pathway is a promising target for the development of new antifungals since its enzymes are essential for fungal cell growth. Appropriate screening assays are therefore needed that allow the identification of potential inhibitors.
Maximilian Liebl +6 more
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Combination of Entner-Doudoroff pathway with MEP increases isoprene production in engineered Escherichia coli. [PDF]
PLoS ONE, 2013 Embden-Meyerhof pathway (EMP) in tandem with 2-C-methyl-D-erythritol 4-phosphate pathway (MEP) is commonly used for isoprenoid biosynthesis in E. coli. However, this combination has limitations as EMP generates an imbalanced distribution of pyruvate and ...
Huaiwei Liu +7 more
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CHIMIA, 2009 Isoprenoids (or terpenoids) are a large and structurally diverse class of biomolecules that are essential for the survival of all forms of life.
Christopher J. Thibodeaux, Hung-wen Liu
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Combining genotype improvement and statistical media optimization for isoprenoid production in E. coli. [PDF]
PLoS ONE, 2013 Isoprenoids are a large and diverse class of compounds that includes many high value natural products and are thus in great demand. To meet the increasing demand for isoprenoid compounds, metabolic engineering of microbes has been used to produce ...
Congqiang Zhang +5 more
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Current Plant Biology, 2021 Carotenoids are long conjugated isoprenoid molecules with over 1117 identified structures, belongs to the class of hydrocarbons, involved in a range of biological processes in plants and humans.
Prashant Swapnil +5 more
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Erratum: Targeting the Isoprenoid Pathway in Choleste Biosynthesis: An Approach to Identify Isoprenoid Biosynthesis Inhibitors. [PDF]
Arch Pharm (Weinheim)europepmc +2 more sources