Results 71 to 80 of about 13,872 (224)

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Phytochrome-dependent temperature perception modulates isoprenoid metabolism [PDF]

, 2020
Changes in environmental temperature influence many aspects of plant metabolism; however, the underlying regulatory mechanisms remain poorly understood.
Bermudez Salazar, Luisa, De Haro, L. A., Haslam, Richard P., Conte, M., Bianchetti, R., Freschi, Luciano, Fernie, A. R., de Haro, L., Bianchetti, Ricardo, Fernie, Alisdair R., Conte, Mariana, Rossi, M., Haslam, R., Bianchetti, R. E., Bermudez, L, Michaelson, L., Fernie, A., Freschi, L., Michaelson, L. V., Bermudez, L., Haslam, R. P., Michaelson, Louise, Bermúdez, Luisa, De Luca, B., Demarco, D., de Haro, Luis Alejandro, Michaelson, Louise V., De Luca, Belen, Rossi, Magdalena, Bianchetti, Ricardo E., de Luca, Maria Belén, Carrari, F., Demarco, Diego, Carrari, Fernando, Rosado, Daniele, Carrari, Fernando Oscar, Rosado, D.   +36 more
core   +1 more source

Dissecting the genetic basis of climatic adaptation in wild relatives (Malus baccata) for climate‐resilient apple breeding

Journal of Integrative Plant Biology, EarlyView.
This comprehensive map of genetic variation in wild apple (Malus baccata) and set of key genes associated with adaptation to temperature, precipitation, and soil properties establishes a foundation for breeding climate‐resilient apple cultivars and conserving the genetic resources of wild crop relatives.
Ying Su, Yani Hao, Xuejing Cao, Lin Wang, Zhiqi Xu, Fan Zhang, Zhiyao Ma, Xu Wang, Jiacui Li, Tianrong Fan, Ruoyan Zhao, Zhongqi Liu, Wenrui Wang, Yingchun Zhang, Xuanwen Yang, Sifan Yang, Dajiang Wang, Kun Wang, Simiao Sun, Zichen Li, Wen Tian, Yanming Sun, Zhao Liu, Yanshuai Xu, Hua Xiao, Yanling Peng, Xiaodong Xu, Ruirui Liu, Xinmin Tian, Yongfeng Zhou, Yuan Gao   +30 more
wiley   +1 more source

Antibiotic fosmidomycin protects bacteria from cell wall perturbations by antagonizing oxidative damage-mediated cell lysis

Frontiers in Microbiology
Cell wall peptidoglycan is a defining component of bacterial cells, and its biosynthesis is a major target for medically important antibiotics. Recent studies have revealed that antibiotics can kill cells not only by their direct effects on wall ...
Yoshikazu Kawai, Jeff Errington
doaj   +1 more source

Towards an integrated molecular understanding of plant hormones

Journal of Integrative Plant Biology, EarlyView.
This review offers a comprehensive overview of the nine plant hormones, delving into their biosynthesis, transport, signaling and crosstalk mechanisms. Because the complexity of plant hormonal control goes beyond these core elements, additional specific features are discussed. Lastly, this review highlights how fundamental insights drive hormonal‐based
Louise Vilain, Marie‐Laure Fauconnier, Manon Genva   +2 more
wiley   +1 more source

New Insight into Isoprenoid Biosynthesis in the Cyanobacterium Synechocystis sp. strain PCC 6803 [PDF]

, 2006
In cyanobacteria, many compounds including chlorophylls, carotenoids, and quinones are synthesized from the isoprenoid precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). These Csub5 compounds are products of the well-studied
Poliquin, Kelly Ann
core  

The non-mevalonate MEP pathway of isoprenoid biosynthesis.

, 2013
Isoprenoids are derived from the basic 5-carbon isoprenoid building blocks isopentenyl pyrophosphate (IPP) and its isomer, dimethylallyl pyrophosphate (DMAPP).
Audrey R. Odom (336744)
core   +1 more source

Screening of Potential Antibiotics, Inhibitors of the Nonmevalonate Pathway of Isoprenoid Biosynthesis (2-C-Methyl-D-Erythritol-2,4-Cyclodiphosphate Derivatives)

Антибиотики и Химиотерапия, 2020
The recently discovered nonmevalonate pathway of isoprenoid biosynthesis Is a prospective target in screening of new antibiotics. Because of the absence of the pathway in the animal cells, the specific inhibitors of the pathway will be a new class of ...
YU. V. Ershov, K. V. Mazikin, D. N. Ostrovsky   +2 more
doaj  

Natural variation in OsMYB305 downregulating cytokinin‐mediated inhibition of leaf senescence contributes to regional adaptation in rice

New Phytologist, EarlyView.
Proposed regulatory model of OsMYB305 in leaf senescence. Summary Accumulating evidence has identified transcription factors (TFs) as key regulators of the onset and progression of leaf senescence. However, the regulatory role of the rice myeloblastosis (MYB) TF OsMYB305 in this process remains largely unknown.
Boyeong Kim, Jinah Kim, Yejin Shim, Jinku Kang, Hyeryung Yoon, Sung‐Hwan Cho, Nam‐Chon Paek, Kiyoon Kang   +7 more
wiley   +1 more source

The lytB gene of Escherichia coli is essential and specifies a product needed for isoprenoid biosynthesis

, 2001
LytB and GcpE, because they are codistributed with other pathway enzymes, have been predicted to catalyze unknown steps in the nonmevalonate pathway for isoprenoid biosynthesis.
McLennan, Neil, Coulson, Andrew, McAteer, Sean, Masters, Millicent/Mrs Donachie   +3 more
core