Results 71 to 80 of about 383 (148)

Genome-Wide Association Study and Pathway-Level Analysis of Kernel Color in Maize

G3: Genes, Genomes, Genetics, 2019
Rapid development and adoption of biofortified, provitamin A-dense orange maize (Zea mays L.) varieties could be facilitated by a greater understanding of the natural variation underlying kernel color, including as it relates to carotenoid biosynthesis ...
Brenda F. Owens, Deepu Mathew, Christine H. Diepenbrock, Tyler Tiede, Di Wu, Maria Mateos-Hernandez, Michael A. Gore, Torbert Rocheford   +7 more
doaj   +1 more source

Evolution‐Inspired Engineering of Diterpene Biosynthesis via Chloroplast Genome Modification

Plant Biotechnology Journal, EarlyView.
ABSTRACT Terpenes constitute the largest and most structurally diverse class of plant secondary metabolites, with critical roles in plant‐environment interactions and broad industrial applications. Although nuclear genome engineering of terpene pathways has been extensively explored, chloroplast genome engineering remains largely undeveloped, with most
Alessandro Occhialini, Xinlu Chen, Samantha A. Miller, Mohammad Majdi, Ivette A. Fuentes Quispe, Gabriella King, Feng Chen   +6 more
wiley   +1 more source

Functional characterization and evolution of the isotuberculosinol operon in Mycobacterium tuberculosis and related Mycobacteria

Frontiers in Microbiology, 2012
Terpenoid metabolites are important to the cellular function, structural integrity, and pathogenesis of the human-specific pathogen Mycobacterium tuberculosis (Mtb).
Reuben J Peters, Francis M Mann, Meimei eXu, Emily K Davenport   +3 more
doaj   +1 more source

Enzymes of the mevalonate pathway of isoprenoid biosynthesis [PDF]

Archives of Biochemistry and Biophysics, 2011
The mevalonate pathway accounts for conversion of acetyl-CoA to isopentenyl 5-diphosphate, the versatile precursor of polyisoprenoid metabolites and natural products. The pathway functions in most eukaryotes, archaea, and some eubacteria. Only recently has much of the functional and structural basis for this metabolism been reported.
openaire   +2 more sources

Concurrent Measurement of O2 Production and Isoprene Emission During Photosynthesis: Pros, Cons and Metabolic Implications of Responses to Light, CO2 and Temperature

Plant, Cell &Environment, EarlyView.
ABSTRACT Traditional leaf gas exchange experiments have focused on net CO2 exchange (Anet). Here, using California poplar (Populus trichocarpa), we coupled measurements of net oxygen production (NOP), isoprene emissions and δ18O in O2 to traditional CO2/H2O gas exchange with chlorophyll fluorescence, and measured light, CO2 and temperature response ...
Kolby Jeremiah Jardine, Suman Som, Luiza Beraldi Gallo, Jilian Demus, Tomas Ferreira Domingues, Christina Marie Wistrom, Lianhong Gu, Guillaume Tcherkez, Ülo Niinemets   +8 more
wiley   +1 more source

Effect of fosmidomycin on metabolic and transcript profiles of the methylerythritol phosphate pathway in Plasmodium falciparum

Memorias do Instituto Oswaldo Cruz, 2007
In Plasmodium falciparum, the formation of isopentenyl diphosphate and dimethylallyl diphosphate, central intermediates in the biosynthesis of isoprenoids, occurs via the methylerythritol phosphate (MEP) pathway.
María B Cassera, Emilio F Merino, Valnice J Peres, Emilia A Kimura, Gerhard Wunderlich, Alejandro M Katzin   +5 more
doaj  

Renal coenzyme A (CoA) production from VB5 fuels stem cell proliferation and tumor growth

Nature Communications
Coenzyme A (CoA), derived from Vitamin B5 (VB5; also called pantothenate), is essential for lipid metabolism, energy production, and cell proliferation. While the intracellular functions of CoA are well-characterized, much less is known about its tissue ...
Ting Miao, Ying Liu, Mujeeb Qadiri, Amaury Dasseux, John M. Asara, Yanhui Hu, Xiaomei Sun, Luz del Carmen Pliego-Alcántara, Christian C. Dibble, Norbert Perrimon   +9 more
doaj   +1 more source

Diurnal Variations in Photochemical Energy Utilization and Osmotic Adjustments in Black Poplar Leaves Under Progressive Water Stress

Plant, Cell &Environment, EarlyView.
ABSTRACT Drought limits the productivity of fast‐growing woody crops, although the metabolic adjustments conferring water stress tolerance remain poorly understood. We investigated the responses of Populus nigra seedlings to water stress by integrating daily physiological measurements and NMR metabolomic analyses.
Antonella Gori, Mauro Centritto, Anatoly P. Sobolev, Giovanni Marino, Francesco Loreto, Francesca Alderotti, Cecilia Brunetti   +6 more
wiley   +1 more source

Isoprene‐Emitting Transgenic Tobacco Shapes Root Microbiome and Enhances Growth of Co‐Cultivated Non‐Emitting Plants

Plant, Cell &Environment, EarlyView.
ABSTRACT Isoprene is the most abundant biogenic volatile organic compound emitted by terrestrial vegetation. Here we report the impact of isoprene on root‐associated microbiomes. Using isoprene‐emitting (IE) transgenic tobacco and isogenic non‐emitting (NE) controls, we performed co‐cultivation experiments in natural soil and analysed plant phenotypes ...
Manuel Bellucci, Mohammad Golam Mostofa, Gian Maria Niccolò Benucci, Ahmad Humayan Kabir, Imran Khan, Marco Lombardi, Vittoria Locato, Gregory Bonito, Francesco Loreto, Thomas D. Sharkey   +9 more
wiley   +1 more source

Engineering metabolic pathways in Amycolatopsis japonicum for the optimization of the precursor supply for heterologous brasilicardin congeners production

Synthetic and Systems Biotechnology, 2018
The isoprenoid brasilicardin A is a promising immunosuppressant compound with a unique mode of action, high potency and reduced toxicity compared to today's standard drugs.
Paul N. Schwarz, Luisa Roller, Andreas Kulik, Wolfgang Wohlleben, Evi Stegmann   +4 more
doaj   +1 more source