Evolution‐Inspired Engineering of Diterpene Biosynthesis via Chloroplast Genome Modification
ABSTRACT Terpenes constitute the largest and most structurally diverse class of plant secondary metabolites, with critical roles in plant‐environment interactions and broad industrial applications. Although nuclear genome engineering of terpene pathways has been extensively explored, chloroplast genome engineering remains largely undeveloped, with most
Alessandro Occhialini +6 more
wiley +1 more source
HDR, the last enzyme in the MEP pathway, differently regulates isoprenoid biosynthesis in two woody plants. [PDF]
Krause T +9 more
europepmc +1 more source
ABSTRACT Drought limits the productivity of fast‐growing woody crops, although the metabolic adjustments conferring water stress tolerance remain poorly understood. We investigated the responses of Populus nigra seedlings to water stress by integrating daily physiological measurements and NMR metabolomic analyses.
Antonella Gori +6 more
wiley +1 more source
Glycophosphatidylinositol (GPI) anchors are the predominant glycoconjugate in Plasmodium parasites, enabling modified proteins to associate with biological membranes.
Michaela S Bulloch +5 more
doaj +1 more source
Correction: Differential Subplastidial Localization and Turnover of Enzymes Involved in Isoprenoid Biosynthesis in Chloroplasts. [PDF]
Perello C +6 more
europepmc +1 more source
3-Hydroxy-3-methylglutaryl coenzyme A reductase genes from Glycine max regulate plant growth and isoprenoid biosynthesis. [PDF]
Wang S +7 more
europepmc +1 more source
The Biosynthesis of Isoprenoids and the Mechanisms Regulating It in Plants
Plants synthesize isopentenyl diphosphate (IPP) via the mevalonate pathway and the methylerythritol phosphate (MEP) pathway. IPP is condensed to its allylic isomer, dimethylallyl diphosphate, to yield geranylgeranyl diphosphate, a common precursor for the production of cyclic diterpenoids.
openaire +2 more sources
A redundant isoprenoid biosynthetic pathway supports Staphylococcus aureus metabolic versatility
Isoprenoids are ubiquitous molecules that serve as fundamental building blocks for life. In bacteria, isoprenoids are precursors for carotenoid pigments, respiratory cofactors, and essential sugar carrier lipids, such as lipid II.
Troy A. Burtchett +10 more
doaj +1 more source
Uncovering the functional residues of Arabidopsis isoprenoid biosynthesis enzyme HDS. [PDF]
Wang JZ +11 more
europepmc +1 more source
The Nonmevalonate Pathway of Isoprenoid Biosynthesis Supports Anaerobic Growth of Listeria monocytogenes. [PDF]
Lee ED, Navas KI, Portnoy DA.
europepmc +1 more source

