Results 1 to 10 of about 40,846 (271)
Recent Advances in Synthetic Isoquinoline-Based Derivatives in Drug Design [PDF]
MoleculesCompounds based on an isoquinoline scaffold (benzo[c]pyridine) display a broad spectrum of biological activities. In recent years, studies have focused mainly on their anticancer properties.
Łukasz Balewski, Anita Kornicka
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Synthesis and Anti-HIV Activity of a Novel Series of Isoquinoline-Based CXCR4 Antagonists
Molecules, 2021 An expansion of the structure–activity relationship study of CXCR4 antagonists led to the synthesis of a series of isoquinolines, bearing a tetrahydroquinoline or a 3-methylpyridinyl moiety as head group.
Mastaneh Safarnejad Shad +6 more
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Dess–Martin Periodinane-Mediated Oxidative Coupling Reaction of Isoquinoline with Benzyl Bromide
Molecules, 2023 Dess–Martin periodinane (DMP) is a broadly applicable oxidant in chemical synthesis. In this work, an efficient and convenient synthesis of N-substituted isoquinolinone derivatives mediated by DMP was achieved through the oxidative coupling reaction of ...
Chunmei Yang +5 more
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Recent Advances in the Synthesis of Isoquinoline-Fused Benzimidazoles
Molecules, 2022 This review includes recent developments in the synthesis of benzo[4,5]imidazo[2,1-a]isoquinolines with particular attention given to categorizing protocols based on the structural features of the ring architecture and crystallographically characterized ...
Dylan J. Twardy +3 more
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Beilstein Journal of Organic Chemistry, 2023 The three-component reaction of isoquinolines, dialkyl acetylenedicarboxylates, and 5,6-unsubstituted 1,4-dihydropyridines in acetonitrile at room temperature afforded functionalized isoquinolino[1,2-f][1,6]naphthyridines in good yields and with high ...
Xiu-Yu Chen +4 more
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Acta Chimica Slovenica, 2022 Cyclohexan-1,3-dione (1) reacted with either 2-aminoprop-1-ene-1,1,3-tricarbonitrile (2a) or diethyl 3-amino-2-cyanopent-2-enedioate (2b) to give the 5,6,7,8-tetrahydronaphthalene derivatives 3a and 3b, respectively.
Rafat Milad Mohareb +3 more
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Iridium Corroles Exhibit Weak Near-Infrared Phosphorescence but Efficiently Sensitize Singlet Oxygen Formation. [PDF]
, 2020 Six-coordinate iridium(III) triarylcorrole derivatives, Ir[TpXPC)]L2, where TpXPC = tris(para-X-phenyl)corrole (X = CF3, H, Me, and OCH3) and L = pyridine (py), trimethylamine (tma), isoquinoline (isoq), 4-dimethylaminopyridine (dmap), and 4-picolinic ...
Borisov, Sergey M +3 more
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Partitioning of π-electrons in rings of aza-derivatives of naphthalene [PDF]
Journal of the Serbian Chemical Society, 2007 A recently proposed method for calculating the π-electron contents (EC) of rings of heteroatom-containing polycyclic conjugated molecules was applied to the aza-derivatives of naphthalene.
Gutman Ivan +2 more
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Антибиотики и Химиотерапия, 2020 The growing threat of proliferation of biofilm-forming hospital strains of coagulase-negative staphylococci resistant to antibiotics determines the need for an urgent search for new effective antibacterial compounds, as well as the development of methods
L. I. Kononova +4 more
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Molecules, 2021 N-heteroaryl substituted adamantane-containing amines are of substantial interest for their perspective antiviral and psychotherapeutic activities. Chlorine atom at alpha-position of N-heterocycles has been substituted by the amino group using convenient
Alisa D. Kharlamova +8 more
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