Results 61 to 70 of about 34,528 (221)
Enhanced CO2 Coordinates the Spatial Recruitment of Diazotrophs in Rice Via Root Development
ABSTRACT Understanding the reciprocal interaction between root development and coadapted beneficial microbes in response to elevated CO2 (eCO2) will facilitate the identification of nutrient‐efficient cultivars for sustainable agriculture. Here, systematic morphological, anatomical, chemical and gene expression assays performed under low‐nitrogen ...
Junwen Zhao+12 more
wiley +1 more source
Oxyntomodulin physiology and its therapeutic development in obesity and associated complications
Abstract figure legend Physiological influences of OXM and its emerging insights from evidence on bariatric surgery effects. CCK, cholecystokinin; FGF21, fibroblast growth factor 21; GLUT4, glucose transporter type 4; IRS1, insulin receptor substrate‐1; NNMT, nicotinamide N‐methyltransferase; OXM, oxyntomodulin Abstract Incretins, such as glucagon‐like
Martin T. W. Kueh+3 more
wiley +1 more source
Regioselective reactions of 3,4-pyridynes enabled by the aryne distortion model. [PDF]
The pyridine heterocycle continues to play a vital role in the development of human medicines. More than 100 currently marketed drugs contain this privileged unit, which remains highly sought after synthetically. We report an efficient means to access di-
Garg, Neil K, Goetz, Adam E
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A Facile Palladium Catalysed 3-Component Cascade Route to Functionalised Isoquinolinones and Isoquinolines [PDF]
Palladium catalysed three component cascade process, involving coupling of 2-iodobenzoates, -benzaldehydes, or acetophenones with substituted allenes and ammonium tartrate as an ammonium surrogate, provides a novel and facile route to substituted ...
Ackermann+51 more
core +1 more source
The positive influence of berberine on the nervous system can be attributed to its diverse effects on multiple targets. The effects of berberine include its antioxidant, anti‐apoptotic, anti‐necroptotic, and anti‐inflammatory properties, as well as its ability to induce autophagy.
Xiaolan Wang+5 more
wiley +1 more source
ABSTRACT In this study, we investigated the therapeutic potential of Berberine (BBR), an anti‐inflammatory agent capable of penetrating the blood–brain barrier, for mitigating postoperative cognitive dysfunction (POCD) in aged mice. BBR was administered at a dose of 10 mg/kg daily for 2 weeks and significantly improved cognitive impairments induced by ...
Xuan Li+6 more
wiley +1 more source
Screening of isoquinoline alkaloids for potent lipid metabolism modulation with Caenorhabditis elegans. [PDF]
Metabolic syndrome and related disorders are increasingly prevalent in contemporary society, and thus pose the need for potent agents to control lipid accumulation in the body.
Chow, Yit-Lai, Sato, Fumihiko
core +1 more source
Beckmann Rearrangement in Liquid Sulfur Dioxide. IV. Syntheses of 1-Methyl-3,4-dihydro-isoquinoline and 9-Phenyl-phenanthridine [PDF]
Ritsuro Tada+2 more
openalex +1 more source
N‐heteroaromatic alkyl alcohols and amines are inherently unstable in acidic and/or basic solution due to an irreversible dehydrogenation that proceeds from a minority tautomer. In many cases, this reaction results in quantitative oxidation to the corresponding aldehyde, providing a simple, convenient, and green approach for preparing versatile ...
Omid Ghasemloo+4 more
wiley +1 more source
Hepatotoxicity induced by greater celandine (Chelidonium majus L.): a review of the literature [PDF]
The available literature assessing Chelidonium majus L. (CM) hepatotoxicity potential, and its risk to benefit assessment has been reviewed in this paper.
Busardò, F. P+6 more
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