Results 31 to 40 of about 5,376 (171)

Inositol and Berberine Synergistically Reprogram Endocrine and Ovarian Metabolism in Polycystic Ovary Syndrome

Cell Proliferation, EarlyView.
In a DHEA+HFD‐induced mouse model, Ins/BBR alleviated mitochondrial defects and broadly reprogrammed metabolic landscape in granulosa cells, in specific, restoring nucleotide pools and amino acid turnover, and preventing abnormal long‐chain fatty acid accumulation.
Juan Ge, Chenxiang Zhang, Yilong Zhao, Haiyang Zhao, Shuai Zhu, Tao Tang, Guorui Zhang, Qiang Wang, Hui Wang   +8 more
wiley   +1 more source

Mining key genes of alkaloid synthesis pathway in lotus leaves based on metabolomics and transcriptomics

浙江大学学报. 农业与生命科学版, 2023
In order to explore the molecular mechanism of alkaloid biosynthesis in lotus leaves, metabolomics and transcriptomics sequencing analyses were performed on mature lotus leaves of ‘Taikong Lian’ (high alkaloid content), ‘Juwuba’ (medium alkaloid content)
LI Shuangqin, WANG Zhongyi, ZHAO Wanyue, CHEN Longqing, HU Huizhen   +4 more
doaj   +1 more source

AlkaPlorer: A database‐driven explorer for natural alkaloids and derivatives

Journal of Integrative Plant Biology, EarlyView.
The alkaloid database AlkaPlorer integrates over 130,000 compounds across 12,250 species. By linking chemical structures with biological and evolutionary data, it reveals how these molecules evolve and function. This platform serves as a vital resource for AI‐driven discovery in plant metabolism and modern drug development. ABSTRACT Alkaloids, renowned
Jiahao Li, Tao Zeng, Hongquan Xu, Xu Kang, Minghui Liang, Ruibo Wu   +5 more
wiley   +1 more source

Chapter 19 Isoquinoline Alkaloids

Chemical and Pharmaceutical Bulletin, 1960
From the quaternary alkaloidal fraction of the dried tubers of Stephania cepharantha, two new isoquinoline alkaloids, stecepharine and tetradehydroreticuline have been isolated along with the known compounds, magnoflorine, menisperine, steponine, cyclanoline, oblongine, cis-N-methylcapaurine and 2'-N-methylisotetrandrine.
T, Tanahashi, U, Su, N, Nagakura, H, Nayeshiro   +3 more
openaire   +4 more sources

Unveiling the impact of nitrogen deficiency on alkaloid synthesis in konjac corms (Amorphophallus muelleri Blume)

BMC Plant Biology
Background Konjac corms are known for their alkaloid content, which possesses pharmacological properties. In the primary cultivation areas of konjac, nitrogen deficiency is a common problem that significantly influences alkaloid synthesis.
Ying Qi, Penghua Gao, Shaowu Yang, Lifang Li, Yanguo Ke, Yongteng Zhao, Feiyan Huang, Lei Yu   +7 more
doaj   +1 more source

Curare - Botany, Chemistry, and Pharmacology [PDF]

Acta Amazonica, 1988
Some aspects of curare research carried out over the last 25 years are discussed. Accepting a pharmacological rather than purely ethnological definition means, that curares are not limited to South America but that they are also known from Central Africa
Norman G. Bisset
doaj   +1 more source

Poplar miR1447 Is a Negative Regulator of Disease Resistance Through the SA‐Dependent Pathway

Plant Biotechnology Journal, EarlyView.
ABSTRACT Although microRNA1447 (miR1447) regulates poplar responses to abiotic stress and pest infestation, how miR1447 regulates poplar immunity against pathogens and its underlying molecular mechanisms remain to be elucidated. Here, we revealed that miR1447 functioned as a negative regulator of poplar disease resistance against fungal and bacterial ...
Dandan Xiao, Kaijing Rong, Tiantian Fu, Yicheng Li, Chun Wang, Ke Zhou, Ruen Yu, Xiaoqian Yang, Yuzhang Yang, Yuanyuan Wang, Yanwei Wang, Yonglin Wang   +11 more
wiley   +1 more source

Antifungal alkaloids from Mahonia fortunei against pathogens of postharvest fruit

Natural Products and Bioprospecting, 2023
Postharvest pathogens can affect a wide range of fresh fruit and vegetables, including grapes, resulting in significant profit loss. Isoquinoline alkaloids of Mahonia fortunei, a Chinese herbal medicine, have been used to treat infectious microbes, which
Xiao-Na Wang, Zhao-Jie Wang, Yun Zhao, Huan Wang, Mei-Ling Xiang, Yang-Yang Liu, Li-Xing Zhao, Xiao-Dong Luo   +7 more
doaj   +1 more source

Enhanced CO2 Coordinates the Spatial Recruitment of Diazotrophs in Rice Via Root Development

Plant, Cell &Environment, EarlyView.
ABSTRACT Understanding the reciprocal interaction between root development and coadapted beneficial microbes in response to elevated CO2 (eCO2) will facilitate the identification of nutrient‐efficient cultivars for sustainable agriculture. Here, systematic morphological, anatomical, chemical and gene expression assays performed under low‐nitrogen ...
Junwen Zhao, Yuting Chen, Qi Tao, Lukas Schreiber, Kiran Suresh, Michael Frei, Muhammad Shahedul Alam, Bing Li, Yaping Zhou, Marcel Baer, Frank Hochholdinger, Changquan Wang, Peng Yu   +12 more
wiley   +1 more source

PREPARATIVE SEPARATION OF ISOQUINOLINE ALKALOIDS FROM PHELLODENDRI CORTEX BY PH-ZONE-REFINING COUNTER-CURRENT CHROMATOGRAPHY

Química Nova
pH-Zone-refining counter-current chromatography (PZRCCC) was successfully used for preparative separation isoquinoline alkaloids from Phellodendri Cortex.
Daijie Wang, Shanming Tian, Li Cui, Huijiao Yan, Xiangyun Song, Yuguo Liu, Fei Xu, Junjian Ma   +7 more
doaj   +1 more source