Results 61 to 70 of about 5,376 (171)

In silico Investigation of the Anticancer Activity of Natural Isoquinoline Alkaloids Targeting the Monoamine Oxidase a Enzyme

AUIQ Complementary Biological System
Monoamine oxidase A (MAO-A) has recently been identified as a candidate for cancer therapy due to its roles in tumor development and growth. Conventional approaches for the discovery of MAO-A inhibitors are both costly and time-consuming.
Reham A.Al-Anssari, Anwar H.Ali, OlaAdel Al-Saad, Shaker A.N. Al-Jadaan   +3 more
doaj   +1 more source

Metabolite Profiling and Anticancer Evaluation of Iraqi Haloxylon articulatum Halophyte via LC–HRMS/MS, Molecular Docking, and ADMET Analysis

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
This study investigates the phytochemical composition and biological activities of a hydroalcoholic extract of Haloxylon articulatum. LC‐HRMS/MS identified diverse bioactive compounds, notably N‐caffeoyltyramine and sinapoyltyramine. The extract exhibited strong antioxidant activity and significant cytotoxic effects against gastric cancer cell lines ...
Jihen Abidi, Amal Ben Hassena, Rania Ben Hmida, Łukasz Kulinowski, Erdi Can Aytar, Reyedh R. Al‐Rashidi, Mohamed Bouaziz   +6 more
wiley   +1 more source

Harnessing Piezoelectric Biomaterials for Pathogenic Eradication and Tissue Regeneration

Exploration, Volume 6, Issue 1, February 2026.
This review highlights recent advances in piezoelectric biomaterials for antibacterial therapy and tissue regeneration, discussing material classifications, catalytic mechanisms, property enhancements, biomedical applications, and future challenges in clinical translation.
Wenxuan Mao, Xiaoye Li, Ao He, Meng Ding, Yu Zhang, Zhuo Dai, Qiang Li, Weijun Xiu, Yanling Hu, Yongbin Mou, Dongliang Yang, Heng Dong   +11 more
wiley   +1 more source

The Elevation of LC-ESI-Q-TOF-MS Response in the Analysis of Isoquinoline Alkaloids from Some Papaveraceae and Berberidaceae Representatives

Journal of Analytical Methods in Chemistry, 2017
Twenty-five methanol extracts obtained from various representatives of Papaveraceae and Berberidaceae botanical families (genera: Papaver, Argemone, Eschscholzia, Chelidonium, Glaucium, and Berberis) were screened for their alkaloid content in an ...
Wirginia Kukula-Koch
doaj   +1 more source

Bioactive isoquinoline alkaloids from Cissampelos pareira

Natural Product Research, 2017
The phytochemical and biological investigation of Cissampelos pareira leads to the isolation of one new isoquinoline alkaloid (7) along with six known isoquinoline alkaloids, namely, magnoflorine (1), magnocurarine (2), cissamine (3), curine (4), hayatinine (5) and cycleanine (6).
Manju Bala, Shiv Kumar, Kunal Pratap, Praveen Kumar Verma, Yogendra Padwad, Bikram Singh   +5 more
openaire   +2 more sources

DEHYDROPUNTARENINE AND DEHYDROSAULATINE TO NEW ISOQUINOLINE ALKALOIDS FROM ROOTS OF BERBERIS ACTINACANTHA [PDF]

Journal of Sciences, Islamic Republic of Iran, 1990
The isolation and characterization of two new isoquinoline alkaloids, Dehydropuntarenine and Dehydrosaulatine, obtained during the column chromatography of an alkaloidal fraction from the roots of B. Actinacantha (Berberidaceae) are described.
doaj  

Nanoparticle formation of an antimicrobial peptide induced by sulfated β-cyclodextrin: Application to alkaloid encapsulation

Carbohydrate Polymer Technologies and Applications
The association of polyanionic β-cyclodextrin (βCD) derivatives with the nonaggregating polycationic antimicrobial peptide Dhvar4 was studied in water at 296 K without a buffer to explore their potential for forming nanoparticles capable of encapsulating
Zsombor Miskolczy, Mónika Megyesi, Beáta Mándityné Huszka, István Mándity, László Biczók   +4 more
doaj   +1 more source

Systematic Evaluation of Chromatographic Parameters for Isoquinoline Alkaloids on XB-C18 Core-Shell Column Using Different Mobile Phase Compositions

Journal of Analytical Methods in Chemistry, 2018
Chelidonium majus L. is a rich source of isoquinoline alkaloids with confirmed anti-inflammatory, choleretic, spasmolytic, antitumor, and antimicrobial activities.
Ireneusz Sowa, Sylwia Zielińska, Jan Sawicki, Anna Bogucka-Kocka, Michał Staniak, Ewa Bartusiak-Szcześniak, Maja Podolska-Fajks, Ryszard Kocjan, Magdalena Wójciak-Kosior   +8 more
doaj   +1 more source

CHEMICAL COMPOSITION AND MEASURING THE DISTRIBUTION OF HAEMANTHIDINE BY MALDI-TOF MS IMAGING FROM Crinum scabrum LEAVES [PDF]

Química Nova
Crinum scabrum Herb., a member of the Amaryllidaceae family, is native to Brazil and known for its diverse alkaloid content and biological potential. Previous studies identified crinamine, 6-hydroxycrinamine, and lycorine in this species.
Jennifer B. Pardo, Amanda E. Feu, Faviola A. Vigamonte, Warley de S. Borges   +3 more
doaj   +1 more source

Ultra-performance liquid chromatography coupled with mass spectrometry profiling and evaluation of in vitro anti-Plasmodium falciparum activity of extracts from a Congolese Ancistrocladus species

Discover Chemistry
Malaria remains one of the leading causes of death globally, particularly in developing countries. This study aimed to investigate the antimalarial activity and UPLC-MS profiling of crude extracts from a new Ancistrocladus species collected in Banalia ...
Justin Bazibuhe Safari, Félicien Mushagalusa Kasali, Séverin Muyisa Kavatsurwa   +2 more
doaj   +1 more source