Results 91 to 100 of about 15,657 (274)
Computational understanding of heterocyclisation reactions and synthesis of fluorinated isoquinolines [PDF]
, 2020 275 p.The present thesis deals with three different topics that have in common the formation of carbo- and heterocycles. The whole work is organized as a synergy of experimental and computational studies to provide a deep understanding of the systems of ...
Zanella, Giovanna
core
European Journal of Lipid Science and Technology, EarlyView.Biocompatible and biodegradable liposomes were developed to encapsulate naringenin (N) and berberine (B), enhancing their stability and bioavailability. Their effects on thermogenesis and browning in 3T3‐L1 preadipocyte cells compared to their free forms were investigated.
Elif Didem Örs Demet +7 more
wiley +1 more source
Synthesis and Fluorescent Properties of Novel Isoquinoline Derivatives
Molecules, 2019 Isoquinoline derivatives have attracted great interest for their wide biological and fluorescent properties. In the current study, we focused on the synthesis of a series of novel isoquinoline derivatives substituted at position 3 of the heteroaromatic ...
Łukasz Balewski +5 more
doaj +1 more source
2,8-Disubstituted-1,6-Naphthyridines and 4,6-Disubstituted-Isoquinolines with Potent, Selective Affinity for CDK8/19 [PDF]
, 2016 We demonstrate a designed scaffold-hop approach to the discovery of 2,8-disubstituted-1,6-naphthyridine- and 4,6-disubstituted-isoquinoline-based dual CDK8/19 ligands.
Blagg, Julian +21 more
core +5 more sources
European Journal of Organic Chemistry, Accepted Article.A cyclobutane ring constitutes an interesting scaffold for the development of new materials and drugs. In this work we describe the [2+2] cycloaddition of chalconoid precursors bearing fluorinated and heterocyclic moieties to produce cyclobutane derivatives in solution.
Concepcion Perez-Melero +3 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2013 Sensitised photolyses of ethoxycarbonyl oximes of aromatic and heteroaromatic ketones yielded iminyl radicals, which were characterised by EPR spectroscopy.
Roy T. McBurney, John C. Walton
doaj +1 more source
Memorias do Instituto Oswaldo Cruz, 2009 The molluscicidal activity of Hammada scoparia leaf extracts and the principal alkaloids isolated from them (carnegine and N-methylisosalsoline) were tested against the mollusc gastropod, Galba truncatula, the intermediate host of Fasciola hepatica in ...
R Mezghani-Jarraya +3 more
doaj +1 more source
Rearrangement Reactions for the Synthesis of Some Oxa- and Aza-tricyclic Rings Heterocyclic Compounds [PDF]
, 2015 This review article describes the main results of our research during the last 5-6 years. A series of new rearrangement reactions was discovered and used for the synthesis of novel heterocyclic compounds: furo[2,3-f]isoquinolines, furo[3,2 -f]quinolines,
Hornyánszky, Gábor +3 more
core +2 more sources
ChemistryOpen, EarlyView.Quinazoline represents an important class of heterocycles with diverse medicinal and pharmacological significance. This review systematically examines scholarly efforts toward understanding different synthetic pathways emphasizing the role of metal and non‐metal catalysts including some miscellaneous reagents employed in the synthesis of quinazoline ...
Neha Manhas +4 more
wiley +1 more source
ChemistryOpen, EarlyView.Unprotected glycosyl pyridinium salts may be accessed in a single step from the corresponding unprotected sugar in aqueous solution. Whilst meta‐ and para‐substitution is well tolerated, ortho substitution of the N‐heterocycle inhibits product formation. Electrochemical studies revealed reduction potentials in the range of −0.9 to −1.4 V.
Daniel Chong +2 more
wiley +1 more source