Results 31 to 40 of about 16,127 (272)

Tertiary Alcohols as Radical Precursors for the Introduction of Tertiary Substituents into Heteroarenes [PDF]

open access: yes, 2019
Despite many recent advances in the radical alkylation of electron-deficient heteroarenes since the seminal reports by Minisci and co-workers, methods for the direct incorporation of tertiary alkyl substituents into nitrogen heteroarenes are limited ...
Fishman, DA   +3 more
core   +2 more sources

Biosynthesis of Isoquinoline Alkaloids [PDF]

open access: yesPlanta Medica, 1979
The isoquinoline alkaloids and their biosynthetic relatives include many compounds which show important physiological properties in animals: dopamine, mescaline, morphine, papaverine, and narcotine are pertinent examples. The biosynthetic routes to the members of this family start from the essential aminoacids tyrosine or phenylalanine. Decarboxylation
openaire   +3 more sources

Aminomethylation/hydrogenolysis as an alternative to direct methylation of metalated isoquinolines – a novel total synthesis of the alkaloid 7-hydroxy-6-methoxy-1-methylisoquinoline

open access: yesBeilstein Journal of Organic Chemistry, 2018
Highly-substituted isoquinolines are important scaffolds in syntheses of natural products and in drug development and hence, effective synthetic approaches are required.
Benedikt C. Melzer   +2 more
doaj   +1 more source

Synthesis and Contractile Activity of Substituted 1,2,3,4-Tetrahydroisoquinolines

open access: yesMolecules, 2011
A series of different 1-monosubstituted and 1,1-disubstituted 1,2,3,4-tetrahydro-isoquinolines was synthesized in high yields from different ketoamides.
Iliyana Stefanova   +4 more
doaj   +1 more source

A straightforward synthesis of indazolo[3,2-a]isoquinolin-6-amines [PDF]

open access: yes, 2013
4-Substituted 1-bromoisoquinolin-3-amines were subjected to Suzuki coupling with o-nitrophenylboronic acid to yield 1-(2-nitrophenyl) isoquinolinamines, which participated in Cadogan cyclization with triethyl phosphite under microwave irradiation in a ...
Balog, József   +2 more
core   +1 more source

A Versatile Synthesis of Substituted Isoquinolines [PDF]

open access: yesAngewandte Chemie, 2011
AbstractHighly substituted isoquinolines of extraordinary structural versatility are prepared starting from N‐tert‐butylimines of o‐tolualdehydes.
Andrew G. Myers, Chong Si
openaire   +4 more sources

Rhodium-Catalyzed Oxidative Annulation of 2- or 7-Arylindoles with Alkenes/Alkynes Using Molecular Oxygen as the Sole Oxidant Enabled by Quaternary Ammonium Salt

open access: yesMolecules, 2021
Developing an efficient catalytic system using molecular oxygen as the oxidant for rhodium-catalyzed cross-dehydrogenative coupling remains highly desirable.
Weihui Zhuang   +3 more
doaj   +1 more source

Recent advances using [Cp*Co(CO)I2] catalysts as a powerful tool for C-H functionalisation [PDF]

open access: yes, 2017
Expansion of the synthetic chemists' toolbox is currently a topic of great interest, with successes providing access to novel compounds and more efficient routes towards new and known pharmaceuticals and agrochemicals.
Chirila, Paula G, Whiteoak, Christopher
core   +1 more source

Photoredox Catalysts Based on N‐(Hexyl)benzothioxanthene‐3,4‐dicarboximide for Photopolymerization and 3D Printing Under Visible Light

open access: yesAngewandte Chemie, Volume 137, Issue 30, July 21, 2025.
In this work, two benzothioxanthene imide dyes demonstrate excellent photochemical properties. When used as photocatalysts, they work with amine and iodonium salt or sulfonium salt to form different three‐component systems for effectively initiating photopolymerization under visible light, through photoredox catalysis processes.
Bin Song   +10 more
wiley   +2 more sources

Reactivity of 3-Ethoxycarbonyl Isoquinolinium Salts Towards Various Nucleophilic Reagents: Applications to the Synthesis of New 1,2-Dihydroisoquinoline-3-carboxylates

open access: yesMolecules, 2002
Different types of novel 1,2-disubstituted 1,2-dihydro isoquinolines were synthesized by addition reactions of organolithium, alcoholates and borohydride reagents with various isoquinolinium salts.
Jean Pierre Bazureau   +1 more
doaj   +1 more source

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