A straightforward synthesis of indazolo[3,2-a]isoquinolin-6-amines [PDF]
4-Substituted 1-bromoisoquinolin-3-amines were subjected to Suzuki coupling with o-nitrophenylboronic acid to yield 1-(2-nitrophenyl) isoquinolinamines, which participated in Cadogan cyclization with triethyl phosphite under microwave irradiation in a ...
Balog, József +2 more
core +1 more source
Developing an efficient catalytic system using molecular oxygen as the oxidant for rhodium-catalyzed cross-dehydrogenative coupling remains highly desirable.
Weihui Zhuang +3 more
doaj +1 more source
Iridium-Catalyzed, Silyl-Directed, peri -Borylation of C−H Bonds in Fused Polycyclic Arenes and Heteroarenes [PDF]
peri-Disubstituted naphthalenes exhibit interesting physical properties and unique chemical reactivity, due to the parallel arrangement of the bonds to the two peri-disposed substituents.
Hartwig, John F, Su, Bo
core +1 more source
Asymmetric isocyanide-based multicomponent reactions are elegant, yet challenging, strategies to access valuable N-heterocycles. Here, the authors employ a chiral Mg(II) -N,N′-dioxide catalyst in three- or four-component reactions to obtain chiral ...
Qian Xiong +4 more
doaj +1 more source
Benzo[de]naphtho[1,8-gh]quinolines: synthesis, photophysical studies and nitro explosives detection
A rational synthetic approach to substituted naphtho[1,8-gh]quinolines using intramolecular cyclization in the presence of potassium in the series of (naphthalen-1-yl)isoquinolines is described. The photophysical properties of the obtained compounds were
Igor L. Nikonov +8 more
doaj +1 more source
Dibenzo[a,g]quinolizin-8-ones: synthesis, estrogen receptor affinities, and cytostatic activity [PDF]
A number of acetoxy-substituted dibenzo[a,g]quinolizin-8-ones were synthesized by the reaction of 1-oxoisoquinolines with substituted homophthalic acid anhydride.
Angerer, S. von +4 more
core
Intramolecular cyclization of b,b-difluorostyrenes bearing an iminomethyl or a diazenyl group at the ortho position: synthesis of 3-fluorinated isoquinoline and cinnoline derivatives [PDF]
journal ...
ICHIKAWA Junji +4 more
core +1 more source
Skeletal editing of alkenes via the cascade cleavage of C(sp2)═C(sp2) and C(sp3)─C(sp3) bonds, enabling the insertion of the nitrogen atom and thereby the synthesis of lactam and amide derivatives using nitroarenes as nitrogen atom insertion reagents under light irradiation.
Hongyun Qin +7 more
wiley +1 more source
Two kinds of [3 + 2] cycloaddition intermediates generated from the three-component reactions of 2-bromobenzaldehydes and maleimides with amino esters or amino acids were used for a one-pot N-allylation and intramolecular Heck reactions to form ...
Xiaoming Ma +6 more
doaj +1 more source
Asymmetric Electrophilic alpha-Amidoalkylation, VII1): Generation, Crystal Structure, and Trapping Reactions of a Chiral 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline Derived N-Acyliminium Ion [PDF]
The camphanic acid amide 4 has efficiently been oxidized with triphenylcarbenium tetrafluoroborate (3) to yield the chiral N-acyliminium ion 1. Trapping reactions of 1 with the silyl nucleophiles 7a-c and 10a-f proceeded with stereoselective bond ...
Aledesanmi +15 more
core +1 more source

