Results 61 to 70 of about 1,345 (190)
Conventional and innovative approaches to black fungi control for stone heritage preservation
IUBMB Life, Volume 77, Issue 3, March 2025.Abstract Black Meristematic Fungi (BMF) are characterized by a thick melanized cell wall and an isodiametric cellular expansion. BMF represent one of the most damaging groups of microorganisms causing the deterioration of outdoor exposed stone monuments mainly due to the formation of dark spots and patches leading to the darkening of their surface ...
Domenico Celi +2 more
wiley +1 more source
2-((3R,9bS)-5,5-Dioxido-2,3-dihydro-9bH-benzo[4,5]isothiazolo[3,2-b]oxazol-3-yl)-1-phenylethan-1-one
MolbankA highly efficient method has been developed for preparing 2-((3R,9bS)-5,5-dioxido-2,3-dihydro-9bH-benzo[4,5]isothiazolo[3,2-b]oxazol-3-yl)-1-phenylethan-1-one.
Yeongju Kim, Sung-Gon Kim
doaj +1 more source
Drug Development Research, Volume 86, Issue 1, February 2025.ABSTRACT In this study, hydrazine clubbed thiazole derivatives (3a–3j) were obtained by Hantzsch thiazole synthesis and characterized by MS, 1H NMR, and 13C NMR. The inhibitory potentials of the derivatives against diabetes‐related enzymes such as aldose reductase (AR), α‐glycosidase (α‐GLY), and α‐amylase (α‐AMY) were experimentally determined, and ...
Betül Kaya +6 more
wiley +1 more source
Discovery of novel benzosultam CRBN ligands
Bulletin of the Korean Chemical Society, Volume 46, Issue 1, Page 48-56, January 2025.Five novel benzosultam CRBN ligands were synthesized and evaluated their CRBN binding affinities. The 5‐amino benzosultam ligand (5b) demonstrated a CRBN binding affinity over 20 times stronger than lenalidomide. Molecular docking studies suggest the enhanced binding affinities could be from an additional hydrogen bond of benzosultams with Trp400 of ...
Hoyeong Park +5 more
wiley +1 more source
Natural Product Communications, 2017 Treatment of substituted propargyl methyl ethers with a base and elemental sulfur in the presence of a thiolate ion afforded 2-alkenecarbodithioate esters in good yields.
Kazuaki Shimada +3 more
doaj +1 more source
Pentathiepins are an understudied molecular prism of biological activities
Archiv der Pharmazie, Volume 357, Issue 12, December 2024.Pentathiepins are cyclic sulfur‐rich compounds that possess remarkable chemical stability, unique structural features, and an extraordinary variety of biological activities. Nonetheless, they have only drawn the attention of the scientific community on a few occasions, generally after the serendipitous discovery of some of their properties. This review
Luca Pozzetti, Christopher R. M. Asquith
wiley +1 more source
Unexpected formation of alkynyl-substituted 3-ylidenedihydrobenzo[ d]isothiazole 1,1-dioxides
, 2016 The isothiazole chemistry has been some progress from the year 1956 and since then, their chemical and physical properties have been extensively studied. Due to their particular reactivity, isothiazoles have recently emerged as useful synthetic compounds
Dassonneville, Benjamin +3 more
core
, 2005 The mechanism for the nucleophilic reaction between methylthiolate and 4-bromo-3-methylamino-isothiazole 1,1-dioxide has been investigated on the basis of ab initio, MP2 and DFT calculations.
Pasqualina Trimarco +7 more
core +1 more source
, 1983 Biochemistry Laboratory, Sambalpur University, Sambalpur-768 017 Manuscript received 5 October 1982, accepted 19 July 1983 Several isothiazole esters have been synthesised with a view to evaluate their spasmolytic activities against acetylcholine ...
S. S. MEHER, S. K. NAIK, A. NAYAK
core +1 more source
, 2009 Herein we report a mild and efficient method to synthesize chiral 3-aminosubstituted isothiazole sulfoxides taking advantage of (+)- and (-)-((8,8-dichlorocamphoryl)sulfonyl)oxaziridine under microwave irradiation.
G. Celentano +15 more
core +1 more source