Results 121 to 130 of about 257,349 (337)

Isothiocyanate-Functionalized Mesoporous Silica Nanoparticles as Building Blocks for the Design of Nanovehicles with Optimized Drug Release Profile

Nanomaterials, 2019
A straightforward methodology for the synthesis of isothiocyanate-functionalized mesoporous silica nanoparticles (MSNs) by exposure of aminated MSNs to 1,1′-thiocarbonyldi-2(1H)-pyridone is reported. These nanoparticles are chemically stable, water
Gabriel Martínez-Edo, Maria C. Llinàs, Salvador Borrós, David Sánchez-García   +3 more
doaj   +1 more source

Administration of 4-(α-L-Rhamnosyloxy)-benzyl Isothiocyanate Delays Disease Phenotype in SOD1^G93ARats: A Transgenic Model of Amyotrophic Lateral Sclerosis [PDF]

, 2015
Maria Galuppo, Sabrina Giacoppo, Renato Iori, Gina Rosalinda De Nicola, Placido Bramanti, Emanuela Mazzon   +5 more
openalex   +1 more source

Supplementary Figure Legend from Dietary Chemopreventative Benzyl Isothiocyanate Inhibits Breast Cancer Stem Cells <i>In Vitro</i> and <i>In Vivo</i> [PDF]

, 2023
Su‐Hyeong Kim, Anuradha Sehrawat, Shivendra V. Singh   +2 more
openalex   +1 more source

Multiplexed Luminal Tissue Constructs with Reconfigurable Barriers for Dynamic Modeling of Multi‐Tissue Interactions

Advanced Materials Technologies, EarlyView.
This study describes the fabrication of arrays of luminal tissue constructs for 3D luminal tissue modeling. An oil or media‐filled reservoir between constructs serves as a liquid barrier or bridge to regulate communication between lumens within the array for modeling multi‐tissue interactions in vitro. Abstract Cell‐lined luminal structures are crucial
Mouhita Humayun, José A. Jiménez‐Torres, Chao Li, Jose M. Ayuso, Karina Lugo‐Cintron, Joseph Ulbrich, Benjamin Myers, Sheena C. Kerr, Adeel Ahmed, David J. Beebe   +9 more
wiley   +1 more source

Microwave‐Assisted Aqueous Synthesis of Gelatin‐Norbornene for Hydrogel Crosslinking and Bioprinting

Advanced Materials Technologies, EarlyView.
A microwave‐assisted reaction is utilized to synthesize gelatin‐norbornene (GelNB), achieving a high degree of norbornene functionalization while reducing the macromer's upper critical solution temperature. The resulting GelNB macromer has high solubility at room temperature, facilitating light‐based 3‐dimensional (3D) printing of thiol‐norbornene ...
Jonathan B. Bryan, Chien‐Chi Lin
wiley   +1 more source

Alternating Copolymerization of Epoxides and Isothiocyanates to Diverse Functional Polythioimidocarbonates and Related Block Polymers^† [PDF]

, 2023
Xiao‐Feng Zhu, Xinyu Lu, Cheng‐Kai Xu, Yu‐Bo Fang, Guan‐Wen Yang, Wei Li, Jingdai Wang, Guang‐Peng Wu   +7 more
openalex   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Degradation of Glucosinolates and Formation of Isothiocyanates, Nitriles, Amines, and N,N’-Dialk(En)Yl Thioureas During Domestic Boiling of Red Cabbage

, 2023
Matthias Renz, Lars Andernach, Martin Kaufmann, Sascha Rohn, Franziska S. Hanschen   +4 more
openalex   +1 more source

T Cell Glycoengineering to Modulate Immune‐Tumor Crosstalk: A Universal Non‐Genetic Strategy for Enhanced Tumor Immunotherapy

Advanced Science, EarlyView.
This study describes a T cell surface engineering strategy that integrates polymer materials with tumor immunology, aiming to achieve broad‐spectrum anti‐tumor applications of glycopolymer‐engineered T (G‐T) cells via non‐genetic modification. Glycopolymer engineering generally modulates immune‐tumor crosstalk through specific cell‐cell interactions ...
Lihua Yao, He Yang, Fangjian Shan, Xiaomeng Niu, Yichen Wang, Hengyuan Zhang, Sujian Wang, Gaojian Chen, Hong Chen   +8 more
wiley   +1 more source