Peptide Amphiphiles Hitchhike on Endogenous Biomolecules for Enhanced Cancer Imaging and Therapy
Advanced Materials, EarlyView.Weakly assembled peptide amphiphile nanostructures disassemble in circulation and reassemble with blood biomolecules, mainly lipoproteins. Binding to blood biomolecules prolongs blood circulation and improves accumulation in solid tumors. In the tumor microenvironment, peptide amphiphiles assemble with cholesterol‐rich domains of cell membranes ...
Li Xiang +19 more
wiley +1 more source
An Injection‐Molded Modified Silicone Rubber for Cancer‐on‐Chip Applications
Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.This study describes the characterization and application of an injection‐molded functionalized PDMS fluidic insert for the commercially available Micronit system. Modified PDMS can accommodate cell culture and is able to covalently bind proteins for long‐lasting coatings under flow‐conditions.
Ben J. Haspels +7 more
wiley +1 more source
Anti-carcinogenic activity of 6-methylsulfinylhexyl isothiocyanate-, an active anti-proliferative principal of wasabi (Eutrema wasabi Maxim.) [PDF]
, 1997 Yoko Fuke +4 more
openalex +1 more source
isoThiocyanates. XXIV. (+)-, (-)-, and (+-)-alpha-Methylbenzyl isoThiocyanate. [PDF]
Acta Chemica Scandinavica, 1957 Anders Kjær +4 more
openaire +1 more source
Advanced Materials Technologies, EarlyView.This study describes the fabrication of arrays of luminal tissue constructs for 3D luminal tissue modeling. An oil or media‐filled reservoir between constructs serves as a liquid barrier or bridge to regulate communication between lumens within the array for modeling multi‐tissue interactions in vitro. Abstract Cell‐lined luminal structures are crucial
Mouhita Humayun +9 more
wiley +1 more source
Isothiocyanate-induced Cell Cycle Arrest in a NovelIn VitroExposure Protocol of Human Malignant Melanoma (A375) Cells [PDF]
, 2019 Theodora Mantso +5 more
openalex +1 more source
Microwave‐Assisted Aqueous Synthesis of Gelatin‐Norbornene for Hydrogel Crosslinking and Bioprinting
Advanced Materials Technologies, EarlyView.A microwave‐assisted reaction is utilized to synthesize gelatin‐norbornene (GelNB), achieving a high degree of norbornene functionalization while reducing the macromer's upper critical solution temperature. The resulting GelNB macromer has high solubility at room temperature, facilitating light‐based 3‐dimensional (3D) printing of thiol‐norbornene ...
Jonathan B. Bryan, Chien‐Chi Lin
wiley +1 more source
ETHYLENE POLYMERIZATION WITH NICKEL DIIMINE COMPLEXES CONTAINING PSEUDOHALIDES
Química NovaNickel-diimine complexes DADNiX2 (DAD= 2,6-iPr2-C6H3-N=C(Me)-C(Me)=N-2,6-iPr2-C6H3) containing the non-chelating pseudo-halide ligands isothyocyanate and isoseleniumcyanate (X= NCS 1 and NCSe 2) were synthesized and used in ethylene polymerization ...
Marcos L. Dias +3 more
doaj +1 more source
Modular microporous hydrogels formed from microgel beads with orthogonal thermo-chemical responsivity: Microfluidic fabrication and characterization. [PDF]
, 2019 Despite the significant advances in designing injectable bulk hydrogels, the inability to control the pore interconnectivity and decoupling it from the matrix stiffness has tremendously limited the applicability of stiff, flowable hydrogels for 3D ...
Akouissi, Outman +6 more
core
Cancer Immunotherapy via Disruption of Integrin αvβ3 and CD47 Costabilization on Cancer Cell Surface
Advanced Science, EarlyView.This study identifies a cancer‐specific interaction between CD47 and integrin αvβ3 that facilitates immune evasion. A rationally designed peptide, PSFL‐NK13, disrupts this axis, enhancing macrophage‐mediated phagocytosis and suppressing tumor growth without inducing anemia.
Peng‐Cheng Yu +12 more
wiley +1 more source