Results 261 to 270 of about 258,689 (296)
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ChemInform Abstract: ISOTHIOCYANATES. XXXVIII. N‐ARYLSULFONYLBENZIMIDOYL ISOTHIOCYANATE

Chemischer Informationsdienst, 1980
AbstractDie Titelverbindungen (II) werden durch Umsetzung der Imidchloride (I) mit Ammoniumthiocyanat erhalten.
G. Barnikow, D. Richter
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The clastogenic effects of isothiocyanates

Mutation Research/Genetic Toxicology, 1993
Four isothiocyanates (ITCs), three of which are commonly found in the human diet, were tested for the ability to induce chromosome aberrations in an SV40-transformed Indian muntjac cell line. Whilst allyl ITC was found to be inactive the other three (benzyl ITC, phenethyl ITC and phenyl ITC) were found to be significant inducers of chromosome damage in
Ian T. Johnson, S. R. R. Musk
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Isothiocyanates and Xenobiotic Detoxification

Molecular Nutrition & Food Research, 2018
AbstractThe potential of isothiocyanates to antagonize the carcinogenicity of structurally diverse chemicals has been established in animals. A feasible mechanism of action involves protecting DNA by reducing the availability of the genotoxic metabolites of chemical carcinogens by either inhibiting their generation and/or stimulating their ...
Costas Ioannides   +3 more
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Biological targets of isothiocyanates

Biochimica et Biophysica Acta (BBA) - General Subjects, 2011
Isothiocyanates are phytochemicals with a broad array of effects in biological systems. Bioactivity includes the stimulation of cellular antioxidant systems, induction of apoptosis and interference with cytokine production and activity. Epidemiological evidence and experimental studies indicate that naturally occurring isothiocyanates and synthetic ...
Mark B. Hampton, Kristin K. Brown
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Genetic Incorporation of a Reactive Isothiocyanate Group into Proteins.

Angewandte Chemie, 2016
Methods for the site-specific modification of proteins are useful for introducing biological probes into proteins and engineering proteins with novel activities.
Weimin Xuan   +3 more
semanticscholar   +1 more source

Isothiocyanates in Cancer Prevention

Drug Metabolism Reviews, 2004
Isothiocyanates are sulfur-containing compounds which are largely responsible for the typical flavor of cruciferous vegetables. In animals and humans they are conjugated with glutathione; the first product of this reaction is a dithiocarbamate, which can be ultimately metabolized to the corresponding mercapturic acid, excreted in urine.
Franca Bianchini, Harri Vainio
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ChemInform Abstract: OXALYL ISOTHIOCYANATES AND CARBONYL HALIDE ISOTHIOCYANATES

Chemischer Informationsdienst, 1981
AbstractReaktion von Ethoxalylchlorid (I) mit 1 Moläquiv. Ammoniumrhodanid (II) in flüssigem SO, bei ‐22°C liefert das Isothiocyanat (III).
J. C. Jochims, R. Bunnenberg
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Tetraalkylammonium Uranyl Isothiocyanates

Inorganic Chemistry, 2012
Three tetraalkylammonium uranyl isothiocyanates, [(CH(3))(4)N](3)UO(2)(NCS)(5) (1), [(C(2)H(5))(4)N](3)UO(2)(NCS)(5) (2), and [(C(3)H(7))(4)N](3)UO(2)(NCS)(5) (3), have been synthesized from aqueous solution and their structures determined by single-crystal X-ray diffraction. All of the compounds consist of the uranyl cation equatorially coordinated to
Lynda Soderholm   +2 more
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Structure of isothiocyanate methemoglobin

Journal of Molecular Biology, 1981
Abstract The structure of the complex of the ambidentate ligand thiocyanate with horse methemoglobin was compared with that of acid methemoglobin and azide methemoglobin by X-ray difference Fourier techniques. Thiocyanate is co-ordinated to iron exclusively by its nitrogen atom, and thus forms the isothiocyanate complex.
Keith Moffat, Zbigniew R. Korszun
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Inhibition of papain by isothiocyanates

Biochimica et Biophysica Acta (BBA) - Enzymology, 1976
During the tapping of papaya latex for papain (EC 3.4.22.2), benzyl isothiocyanate is enzymatically produced from benzylglucosinolate, a major component of the latex fluid. Benzyl isothiocyanate inhibits papain hydrolysis of alpha-N-benzoyl-L-arginine ethyl ester (Bz-Arg-OEt).
C.S. Tang, Wen-Jing Tang
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