Results 121 to 130 of about 16,389 (298)
Mechanism of action of isothiocyanates: the induction of ARE-regulated genes is associated with activation of ERK and JNK and the phosphorylation and nuclear translocation of Nrf2 [PDF]
, 2006 Changjiang Xu +9 more
openalex +1 more source
Surface Engineered Biomolecular Condensates for Targeted Cell Cytotoxicity
Advanced Science, EarlyView.Interfacial engineering of biomolecular condensates with a decanoic acid (DA) membrane enables molecular‐weight‐gated enzyme localization. Small biomolecules (≤60 kDa) enrich internally, while high‐molecular‐weight alkaline phosphatase (ALP) localizes at the interface.
Chengying Yin +6 more
wiley +1 more source
Advanced Science, EarlyView.Utilizing molecular engineering for network design, three pesticide‐loaded organogels (PLOs) carriers exhibiting varying degrees of flexibility were prepared. The mechanical properties of these carriers, tunable via their network molecular structures, enhance their structural adaptability and retention stability at biological interfaces, thereby ...
Yue Wang +6 more
wiley +1 more source
Cross‐Platform Biosensing of Immune Receptors Using Peptide‐Functionalized Graphene
Advanced Science, EarlyView.A peptide‐functionalized graphene biosensor enables sensitive and selective detection of living immune cells. Targeting Formyl‐Peptide Receptor 2 (FPR2), the assay is demonstrated on model cells and primary human neutrophils. The same assay is applied to two complementary platforms: graphene‐enhanced surface plasmon resonance for optical benchmarking ...
Ahmar Hasnain +5 more
wiley +1 more source
Advanced Science, EarlyView.Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng +20 more
wiley +1 more source
Hydrolysis of Glucosinolates to Isothiocyanates after Ingestion of Raw or Microwaved Cabbage by Human Volunteers [PDF]
, 2004 Gabrielle Rouzaud +2 more
openalex +1 more source
Advanced Science, EarlyView.A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu +15 more
wiley +1 more source
Administration of 4-(α-L-Rhamnosyloxy)-benzyl Isothiocyanate Delays Disease Phenotype in SOD1G93ARats: A Transgenic Model of Amyotrophic Lateral Sclerosis [PDF]
, 2015 Maria Galuppo +5 more
openalex +1 more source