Results 131 to 140 of about 57,431 (346)
Metabolic Activity of Radish Sprouts Derived Isothiocyanates in Drosophila melanogaster
We used Drosophila melanogaster as a model system to study the absorption, metabolism and potential health benefits of plant bioactives derived from radish sprouts (Raphanus sativus cv.
N. Baenas +6 more
semanticscholar +1 more source
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma +16 more
wiley +1 more source
Effect of Heavy Metal Ions and Carbohydrates on the Activity of Cauliflower (Brassica oleracea Var. botrytis) Myrosinase [PDF]
Myrosinase is an enzyme of cruciferous vegetables, hydrolyse glucosinolates. The breakdown products are involved in plant defence against insect and also have anti-fungal property.
Prakash, Om +3 more
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We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong +8 more
wiley +1 more source
Watercress has long been believed to affect macroinvertebrate communities in chalk streams. Harvesting and washing watercress damages plant tissues and releases isothiocyanates which are potential toxicants to Gammarus pulex (L.).
Dixon, M.J., Shaw, P.J.
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Effects of Brassicaceae Isothiocyanates on Prostate Cancer
Despite the major progress made in the field of cancer biology, cancer is still one of the leading causes of mortality, and prostate cancer (PCa) is one of the most encountered malignancies among men.
S. Novío +4 more
semanticscholar +1 more source
This study constructed the W1/O/W2 emulsion–based targeted therapy delivery system for ulcerative colitis (UC) utilizing LCC as surfactant for the first time. This multifunctional emulsion offered certain therapeutic advantages for UC, including targeted colonic delivery of active compounds, synergistic modulation of gut microbiota through combined ...
Qian Wu +9 more
wiley +1 more source
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li +6 more
wiley +1 more source
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo +14 more
wiley +1 more source
Japanese irogane alloys and patination – a study of production and application [PDF]
Japanese metalworkers use a wide range of irogane alloys (shakudo, shibuichi), which are colored with a single patination solution (niiro). This approach allows different alloys to be combined in one piece and patinated, producing a multi-colored piece ...
Jones, Alan Hywel, O'Dubhghaill, Coilin
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