Results 121 to 130 of about 57,431 (346)

Glucosinolates in plant protection strategies: A review [PDF]

, 2012
This review discusses the importance of glucosinolates in plant protection. The Brassicaceae, which are cultivated worldwide, use glucosinolates and their decomposition products to defend themselves against attacks by harmful organisms.
Ban D., Ban Goreta Smiljana, Bohinc Tanja, Trdan S.   +3 more
core   +1 more source

Synthesis of 6-Phosphorylated Phenanthridines by Mn(II)-Promoted Tandem Reactions of 2-Biaryl Isothiocyanates with Phosphine Oxides.

Journal of Organic Chemistry, 2017
A novel Mn(II)-promoted tandem phosphorylation/cyclization reaction of 2-biaryl isothiocyanates with phosphine oxides is described. This is the first general method to synthesize 6-phosporylated phenanthridines from 2-biaryl isothiocyanates. The approach
Weisi Guo, Qian Dou, Jian‐Guo Hou, L. Wen, Ming Li   +4 more
semanticscholar   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

Glutathione-Mediated Neuroprotection Against Methylmercury Neurotoxicity in Cortical Culture is Dependent on MRP1 [PDF]

, 2012
Methylmercury (MeHg) exposure at high concentrations poses significant neurotoxic threat to humans worldwide. The present study investigated the mechanisms of glutathione-mediated attenuation of MeHg neurotoxicity in primary cortical culture. MeHg (5 μM)
Liu, Xiaoqian, Lobner, Doug, Nowakowski, Andrew B., Petering, David H., Rush, Travis   +4 more
core   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

In vitro screening of the effect of three glucosinolate derived nitriles on soil-borne fungi [PDF]

, 2006
Glucosinolates are allelochemicals present in all plants of the order Capparales that are hydrolysed by endogenous enzymes (myrosinases) forming a variety of compounds with biological activity.
Bellostas, Natalia, Casanova, Esther, Garcia-Mina, Jose Maria, Sorensen, Hilmer, Sorensen, Jens Christian   +4 more
core  

Isothiocyanates as effective agents against enterohemorrhagic Escherichia coli: insight to the mode of action

Scientific Reports, 2016
Production of Shiga toxins by enterohemorrhagic Escherichia coli (EHEC) which is responsible for the pathogenicity of these strains, is strictly correlated with induction of lambdoid bacteriophages present in the host’s genome, replication of phage DNA ...
D. Nowicki, Olga Rodzik, A. Herman-Antosiewicz, A. Szalewska-Pałasz   +3 more
semanticscholar   +1 more source

Highly Biomimetic Ectodermal Epithelial Organoids for Epithelial Barrier Stimulation Assays

Advanced Science, EarlyView.
ABSTRACT Evaluating the potential toxicity of pharmaceuticals and biomaterials to ectodermal epithelia, such as the oral mucosa and skin, is indispensable in pre‐clinical assessments. However, this remains a challenge primarily owing to the lack of physiologically relevant and accurate screening models.
Yiming Chen, Yuman Li, Chenyu Deng, Leran Li, Zhewen Hu, Boon Chin Heng, Yuting Niu, Shiyu Sun, Min Gao, Xiaopei Chi, Ying He, Mingming Xu, Ying Huang, Xuliang Deng   +13 more
wiley   +1 more source

Synthesis, Computational Study, and In Vitro α-Glucosidase Inhibitory Action of Thiourea Derivatives Based on 3-Aminopyridin-2(1H)-Ones

Molecules
Reactions with allyl-, acetyl-, and phenylisothiocyanate have been studied on the basis of 3-amino-4,6-dimethylpyridine-2(1H)-one, 3-amino-4-phenylpyridine-2-one, and 3-amino-4-(thiophene-2-yl)pyridine-2(1H)-one (benzoyl-)isothiocyanates, and the ...
Zarina Shulgau, Irina Palamarchuk, Shynggys Sergazy, Assel Urazbayeva, Alexander Gulyayev, Yerlan Ramankulov, Ivan Kulakov   +6 more
doaj   +1 more source

Hydrogen Sulfide (H₂S) Releasing Capacity of Isothiocyanates from Moringa oleifera Lam.

Molecules, 2018
Moringa oleifera Lam. is rich in phytochemical compounds especially glucosinolates (GSs) and isothiocyanates (ITCs), which are active compounds for cancer chemoprevention benefits of Brassicaceae vegetables.
Xiangshe Wang, Yunjiao Liu, Xingdi Liu, Yi Lin, Xueqin Zheng, Yuyun Lu   +5 more
doaj   +1 more source