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In recent years, isothiocyanates (ITCs), bioactive compounds primarily derived from Brassicaceae vegetables and herbs, have gained significant attention within the biomedical field due to their versatile biological effects.
Barbara Wollenberg +2 more
exaly +5 more sources
Isothiocyanates: a review [PDF]
Isothiocyanates (ITCs) are naturally occurring molecules belonging to highly reactive organosulphur synthons, with the general structure R–N=C=S. The precursor molecule glucosinolate anions are hydrolyzed enzymatically (under the effect of myrosinase ...
Chandra Kala* +4 more
doaj +2 more sources
The rapid generation of isothiocyanates in flow [PDF]
Isothiocyanates are versatile starting materials for a wide range of chemical reactions. However, their high nucleophilic susceptibility means they are best prepared and used immediately.
Marcus Baumann, Ian R. Baxendale
doaj +3 more sources
Isothiocyanates are biologically active secondary metabolites liberated via enzymatic hydrolysis of their sulfur enriched precursors, glucosinolates, upon tissue plant disruption. The importance of this class of compounds lies in their capacity to induce
Sotiris Kyriakou +5 more
doaj +2 more sources
In this communication we demonstrate that two natural isothiocyanates, sulforaphane (SFN) and erucin (ERN), inhibit autoxidation of lipids at 140 °C but not below 100 °C.
Jakub Cedrowski +3 more
doaj +2 more sources
A new and efficient synthesis of substituted 2-amino-1,3,4-oxadiazoles from isothiocyanates and hydrazides [PDF]
1,3,4-Oxadiazoles are privileged heterocyclic scaffolds with broad bioactivities, holding significant importance in pharmaceutical and agrochemical discovery.
Lei Wu +6 more
doaj +2 more sources
Evaluation and Selection of Thermal Processing Conditions for Safety, Flavor Retention, and Shelf-Life Extension of Fermented Pickled Mustard Greens [PDF]
To address post-acidification, microbial contamination, and quality deterioration in fermented pickled mustard greens after fermentation, this study systematically evaluated the effects of thermal treatment on quality preservation, selected a preferred ...
Qiuming Chen +6 more
doaj +2 more sources
Plasma-Activated Water Dipping of Fresh-Cut Eruca sativa: An Extended Investigation of the Glucosinolate-Myrosinase System and Cellular Responses [PDF]
Plasma-Activated Water (PAW) is an emerging non-thermal technology with potential applications in fresh-cut vegetable preservation. The present study investigated the effect of PAW dipping on the glucosinolate-myrosinase system of rocket salad (Eruca ...
Veronica Lolli +6 more
doaj +2 more sources
Design, Synthesis, and Biological Activity of Isothiocyanate-Triazine Conjugates as AChE and BACE1 Inhibitors [PDF]
The search for new compounds capable of inhibiting the activity of enzymes involved in the development of neurodegenerative diseases, including Alzheimer’s disease, has attracted continuing interest for many years.
Kacper Górecki +8 more
doaj +2 more sources
Recent Advancement in Synthesis of Isothiocyanates [PDF]
Isothiocyanates exhibit various biological characteristics, including antimicrobial, anti-inflammatory, and anticancer properties. Their significance extends to synthetic chemistry, where they serve as valuable platforms for versatile transformations ...
Kei, Murakami, Bumpei, Maeda
core +1 more source

