Results 11 to 20 of about 57,431 (346)

Benefits and risks of the hormetic effects of dietary isothiocyanates on cancer prevention [PDF]

open access: yes, 2014
The isothiocyanate (ITC) sulforaphane (SFN) was shown at low levels (1-5 µM) to promote cell proliferation to 120-143% of the controls in a number of human cell lines, whilst at high levels (10-40 µM) it inhibited such cell proliferation.
A Arlt   +91 more
core   +9 more sources

Beneficial Health Effects of Glucosinolates-Derived Isothiocyanates on Cardiovascular and Neurodegenerative Diseases

open access: yesMolecules, 2022
Neurodegenerative diseases (NDDs) and cardiovascular diseases (CVDs) are illnesses that affect the nervous system and heart, all of which are vital to the human body.
R. Kamal   +8 more
semanticscholar   +1 more source

Effects of Glucosinolate-Derived Isothiocyanates on Fungi: A Comprehensive Review on Direct Effects, Mechanisms, Structure-Activity Relationship Data and Possible Agricultural Applications

open access: yesJournal of Fungi, 2021
Plants heavily rely on chemical defense systems against a variety of stressors. The glucosinolates in the Brassicaceae and some allies are the core molecules of one of the most researched such pathways.
Tamás Plaszkó   +3 more
semanticscholar   +1 more source

Isothiocyanates – A Review of their Health Benefits and Potential Food Applications

open access: yesCurrent Research in Nutrition and Food Science Journal, 2022
Isothiocyanates are the highly reactive organo-sulphur phytochemicals and are product of hydrolysis of glucosinolates which are present mainly in the cruciferous vegetables.
K. Yadav, Jyotika Dhankhar, Preeti Kundu
semanticscholar   +1 more source

Glucosinolates and Isothiocyantes in Processed Rapeseed Determined by HPLC-DAD-qTOF

open access: yesPlants, 2021
Glucosinolates are well known as natural antimicrobials and anticarcinogenic agents. However, these compounds can lose their properties and transform into antinutrients, depending on processing conditions.
Ana Miklavčič Višnjevec   +5 more
doaj   +1 more source

Nanodelivery of Natural Isothiocyanates as a Cancer Therapeutic.

open access: yesFree Radical Biology & Medicine, 2021
Natural isothiocyanates (ITCs) are phytochemicals abundant in cruciferous vegetables with the general structure, R-N=C=S. They are bioactive organosulfur compounds derived from the hydrolysis of glucosinolates by myrosinase.
Qi Wang, Y. Bao
semanticscholar   +1 more source

Chemical Priming by Isothiocyanates Protects Against Intoxication by Products of the Mustard Oil Bomb

open access: yesFrontiers in Plant Science, 2020
In Brassicaceae, tissue damage triggers the mustard oil bomb i.e., activates the degradation of glucosinolates by myrosinases leading to a rapid accumulation of isothiocyanates at the site of damage.
Elena Ferber   +9 more
doaj   +1 more source

Cooking Methods for Preserving Isothiocyanates and Reducing Goitrin in Brassica Vegetables

open access: yesFoods, 2023
Glucosinolates in Brassica vegetables can be hydrolyzed into various products, e.g., chemopreventive agents, isothiocyanates (ITCs) and anti-thyroid substance, goitrin. Cooking can reduce goitrin but destroy isothiocyanates.
Thanaporn Panduang   +3 more
doaj   +1 more source

Variation and Distribution of Glucosinolates in 42 Cultivars of Brassica oleracea Vegetable Crops [PDF]

open access: yes, 2010
Brassica vegetables are known to contain glucosinolates that are precursors for bioactive compounds like isothiocyanates that have been shown to play an important role in human health. This study reports the results of a screening of 11 Brassica oleracea
Dekker, M., Tebbenhoff, S., Verkerk, R.
core   +17 more sources

Assessment of Methodological Pipelines for the Determination of Isothiocyanates Derived from Natural Sources

open access: yesAntioxidants, 2022
Isothiocyanates are biologically active secondary metabolites liberated via enzymatic hydrolysis of their sulfur enriched precursors, glucosinolates, upon tissue plant disruption. The importance of this class of compounds lies in their capacity to induce
Sotiris Kyriakou   +5 more
doaj   +1 more source

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