Results 21 to 30 of about 57,431 (346)

Glucosinolates From Cruciferous Vegetables and Their Potential Role in Chronic Disease: Investigating the Preclinical and Clinical Evidence

Frontiers in Pharmacology, 2021
An increasing body of evidence highlights the strong potential for a diet rich in fruit and vegetables to delay, and often prevent, the onset of chronic diseases, including cardiometabolic, neurological, and musculoskeletal conditions, and certain ...
Emma L. Connolly, Marc Sim, Marc Sim, Nikolaj Travica, Wolfgang Marx, Gemma Beasy, Gordon S. Lynch, Catherine P. Bondonno, Catherine P. Bondonno, Joshua R. Lewis, Joshua R. Lewis, Joshua R. Lewis, Jonathan M. Hodgson, Jonathan M. Hodgson, Lauren C. Blekkenhorst, Lauren C. Blekkenhorst   +15 more
doaj   +1 more source

Biomarker Exploration in Human Peripheral Blood Mononuclear Cells for Monitoring Sulforaphane Treatment Responses in Autism Spectrum Disorder [PDF]

, 2020
Autism Spectrum Disorder (ASD) is one of the most common neurodevelopmental disorders with no drugs treating the core symptoms and no validated biomarkers for clinical use.
Connors, Susan L., Diggins, Eileen, Dinkova-Kostova, Albena, Fahey, Jed W., Liu, Hua, Singh, Kanwaljit, Stephenson, Katherine K., Zimmerman, Andrew W.   +7 more
core   +3 more sources

Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma

Haematologica, 2011
Background Isothiocyanates, a family of phytochemicals found in cruciferous vegetables, have cytotoxic effects against several types of tumor cells. Multiple myeloma is a fatal disease characterized by clonal proliferation of plasma cells in the bone ...
Jana Jakubikova, David Cervi, Melissa Ooi, Kihyun Kim, Sabikun Nahar, Steffen Klippel, Dana Cholujova, Merav Leiba, John F. Daley, Jake Delmore, Joseph Negri, Simona Blotta, Douglas W. McMillin, Teru Hideshima, Paul G. Richardson, Jan Sedlak, Kenneth C. Anderson, Constantine S. Mitsiades   +17 more
doaj   +1 more source

Myrosinase-dependent and –independent formation and control of isothiocyanate products of glucosinolate hydrolysis.

Frontiers in Plant Science, 2015
Brassicales contain a myrosinase enzyme that hydrolyzes glucosinolates to form toxic isothiocyanates, as a defense against bacteria, fungi, insects and herbivores including man.
Donato eAngelino, Edward B Dosz, Jianghao eSun, Jennifer L Hoeflinger, Maxwell L Van Tassell, Pei eChen, James M Harnly, Michael J Miller, Elizabeth H Jeffery   +8 more
doaj   +1 more source

Micellar electrokinetic capillary chromatography—Synchronous monitoring of substrate and products in the myrosinase catalysed hydrolysis of glucosinolates [PDF]

, 2006
A micellar electrokinetic capillary chromatography (MECC) method has been developed for monitoring the myrosinase catalysed hydrolysis of 2-hydroxy substituted glucosinolates and the simultaneous formation of the corresponding degradation products ...
Bellostas, Natalia, Sorensen, Hilmer, Sorensen, Jens Christian   +2 more
core   +1 more source

Effect of stevia supplementation of kale juice spheres on their quality changes during refrigerated shelf life [PDF]

, 2018
Kale is a vegetable with high contents of health–promoting compounds although its consumption as a beverage is highly limited due to its bitter flavour. Nonetheless, the bitter flavour of Brassicas may be masked by sweetening.
Artés Calero, Francisco, Artés Hernández, Francisco de Asís, Collado Marín, Elena, Martínez Hernández, Ginés Benito, Venzke Klug, Tâmmila   +4 more
core   +2 more sources

Volatile composition, antidiabetic, and anti-obesity potential of Brassica incana leaf and flowering top extracts

Pharmaceutical Biology, 2022
Context Brassica incana Ten. (Brassicaceae) is an edible plant with very limited available information. Previous studies have demonstrated the polyphenolic profile and the antioxidant and cytotoxic properties of the leaf and flowering top hydroalcoholic ...
Maria Fernanda Taviano, Sonia Núñez, Adrián Millán-Laleona, Concetta Condurso, Antonella Verzera, Maria Merlino, Monica Ragusa, Natalizia Miceli, Víctor López   +8 more
doaj   +1 more source

Gut microbiota degrades toxic isothiocyanates in a flea beetle pest

Molecular Ecology, 2020
Microbial symbionts of herbivorous insects have been suggested to aid in the detoxification of plant defense compounds; however, quantitative studies on microbial contribution to plant toxin degradation remain scarce.
S. Shukla, F. Beran
semanticscholar   +1 more source

A Lesson Learnt from Food Chemistry—Elevated Temperature Triggers the Antioxidant Action of Two Edible Isothiocyanates: Erucin and Sulforaphane

Antioxidants, 2020
In this communication we demonstrate that two natural isothiocyanates, sulforaphane (SFN) and erucin (ERN), inhibit autoxidation of lipids at 140 °C but not below 100 °C.
Jakub Cedrowski, Kajetan Dąbrowa, Agnieszka Krogul-Sobczak, Grzegorz Litwinienko   +3 more
doaj   +1 more source

‘Kombucha’-like Beverage of Broccoli By-Products: A New Dietary Source of Bioactive Sulforaphane

Beverages, 2023
The objective of this work is the development of a new fermented beverage (‘kombucha’-like), enriched with broccoli by-products as an ingredient, a source of organosulfur compounds, which could be biotransformed into more bioaccessible, bioavailable, and
Berta María Cánovas, Cristina García-Viguera, Sonia Medina, Raúl Domínguez-Perles   +3 more
doaj   +1 more source