Results 41 to 50 of about 20,151 (240)
Antioxidants, 2021 Malignant melanoma is one of the most deadly types of solid cancers, a property mainly attributed to its highly aggressive metastatic form. On the other hand, different classes of isothiocyanates, a class of phytochemicals, present in cruciferous ...
Melina Mitsiogianni +7 more
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An Integrated Metabolomics Study of Glucosinolate Metabolism in Different Brassicaceae Genera
Metabolites, 2020 Glucosinolates are a group of plant secondary metabolites that can be hydrolyzed into a variety of breakdown products such as isothiocyanates, thiocyanates, and nitriles.
Yu Liu +5 more
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Biological activity of glucosinolate derived compounds isolated from seed meal of Brassica crops and evaluated as plant and food protection agents [PDF]
, 2007 Glucosinolates are amino acid derived allelochemicals characteristic of plants of the order Capparales. These compounds are present in seeds of agriculturally common Brassica crops in varying quantities depending on the species (ref).
Bellostas, N. +8 more
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Variation and Distribution of Glucosinolates in 42 Cultivars of Brassica oleracea Vegetable Crops [PDF]
, 2010 Brassica vegetables are known to contain glucosinolates that are precursors for bioactive compounds like isothiocyanates that have been shown to play an important role in human health. This study reports the results of a screening of 11 Brassica oleracea
Dekker, M., Tebbenhoff, S., Verkerk, R.
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Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
Synthesis of Isothiocyanates Using DMT/NMM/TsO− as a New Desulfurization Reagent
Molecules, 2021 Thirty-three alkyl and aryl isothiocyanates, as well as isothiocyanate derivatives from esters of coded amino acids and from esters of unnatural amino acids (6-aminocaproic, 4-(aminomethyl)benzoic, and tranexamic acids), were synthesized with ...
Łukasz Janczewski +2 more
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Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source
The rapid generation of isothiocyanates in flow
Beilstein Journal of Organic Chemistry, 2013 Isothiocyanates are versatile starting materials for a wide range of chemical reactions. However, their high nucleophilic susceptibility means they are best prepared and used immediately.
Marcus Baumann, Ian R. Baxendale
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International Journal of Food Properties, 2022 Several scientific researchers have focused on biological activities of edible plants such as radish. However, there are no researches on the anticancer effect of this plant in human glioblastoma.
Nadhem Aissani, Hichem Sebai
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Glucosinolate hydrolysis compounds for weed control [PDF]
, 2006 Glucosinolates are allelochemicals present in all Brassica plants. Upon hydrolysis by endogenous enzymes they produce a series of biologically active compounds, such as isothiocyanates and their deriva-tives among others.
Bellostas, Natalia +3 more
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