Results 91 to 100 of about 1,834 (212)

trans-Hydroxylation of cyclopent-5-ene[d]isoxazolines [PDF]

open access: yes, 2013
The title reaction has been studied as a variant of the cyclopentane ring functionalization of cyclopent-5-ene[d]isoxazolines as the key intermediates in total synthesis of azaand oxo prostaglandin analogues by nitrileoxides approach.
Antonevich, I. P., Nesterova, S. V.
core  

Synthesis of Isoxazolines by the Electrophilic Chalcogenation of β,γ‑Unsaturated Oximes: Fishing Novel Anti-Inflammatory Agents

open access: yes, 2019
Herein, we describe a new strategy to prepare chalcogen-functionalized isoxazolines. The strategy involves the reaction of β,γ-unsaturated oximes with electrophilic selenium and tellurium species, affording 19 new selenium- and tellurium-containing ...
Mikaela Pinz (7429352)   +11 more
core   +1 more source

Optimising systemic insecticide use to improve malaria control

open access: yesBMJ Global Health, 2019
BackgroundLong-lasting insecticidal nets and indoor residual sprays have significantly reduced the burden of malaria. However, several hurdles remain before elimination can be achieved: mosquito vectors have developed resistance to public health ...
Hannah R Meredith   +2 more
doaj   +1 more source

Base-Catalyzed Isomerization of 2-Isoxazolines Enables a Two-Step Enantioselective Synthesis of β-Hydroxynitriles from Enals

open access: yes, 2016
The asymmetric synthesis of β-hydroxynitriles remains a challenge in organic synthesis. Herein we report a convenient synthesis of β-hydroxynitriles from enantiomerically enriched 3-unsubstituted 2-isoxazolines via a base-catalyzed ring-opening reaction ...
Antti Pohjakallio (2262703)   +2 more
core   +1 more source

Copper-Catalyzed Oxyazidation of Unactivated Alkenes: A Facile Synthesis of Isoxazolines Featuring an Azido Substituent

open access: yes, 2016
A novel and efficient Cu­(OAc)2-catalyzed oxyazidation of unactivated alkenes was developed. The reactions are easy to conduct, occur under mild conditions, and form azido-substituted isoxazolines in good ...
Liping Zhu (25704)   +5 more
core   +1 more source

Copper-Catalyzed Oxyazidation of Unactivated Alkenes: A Facile Synthesis of Isoxazolines Featuring an Azido Substituent

open access: yes, 2014
A novel and efficient Cu(OAc)2-catalyzed oxyazidation of unactivated alkenes was developed. The reactions are easy to conduct, occur under mild conditions, and form azido-substituted isoxazolines in good ...
Zhu, Liping   +11 more
core   +1 more source

Anionic Domino C-O-Heterocyclization Approach for the Synthesis of 5-Vinyl Isoxazolines

open access: yes, 2007
5-Vinyl isoxazolines were isolated in high yields through domino nucleophilic addition–anionic C–O-heterocyclization, when allyl organometallics derived from trans-1,4-dihalobutene were reacted with nitrile ...
Kumar, H.   +7 more
core   +1 more source

Synthesis and Antimicrobial Studies of Some Novel Pyrazoline and Isoxazoline Derivatives

open access: yesE-Journal of Chemistry, 2009
A new series of 1H-3-(4’-substituted phenyl)-5-(6’’-methoxy napthaline)-2-pyrazolines (4a-e) and 1H-3-(4’-substituted phenyl)-5-(6’’-methoxynapthaline)-2-isoxazolines (5a-e) were synthesized by reacting 1-(4’-substituted phenyl)-3-(6’’-methoxynapthaline)-
S. B. jadhav   +3 more
doaj   +1 more source

Synthesis and reductive cleavage of 3-(2-flurophenyl) and 3-(4-flurophenyl)-cyclopent-5-en[d]isoxazolines by raney nickel in trifluroacetic acid

open access: yes, 2020
3-Fluoro arylcycloopent-5-en[d]isoxazolines have been obtained via the 1,3-dipolar cycloaddition of cyclopentadiene to aromatic nitrile oxides. The reductive cleavage of these isoxazolines by Raney nickel in trifluoroacetic acid led to corresponding ...
Antonevich, I. P.   +2 more
core  

A One-Pot Approach to Δ2‑Isoxazolines from Ketones and Arylacetylenes

open access: yes, 2016
The sequential reaction of ketones with arylacetylenes and hydroxylamine in the presence of KOBut/DMSO followed by the treatment of the reaction mixture with H2O and KOH leads to Δ2-isoxazolines in up to 88 ...
Elena Yu. Schmidt (2007184)   +5 more
core   +1 more source

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