Results 21 to 30 of about 26,822 (186)

Evaluation of Itraconazole and in Combination in the Treatment of Resistant and Recurrent Tinea Corporis and Cruris (Comparative Study) [PDF]

Al-Azhar International Medical Journal
Background: One of the most prevalent dermatological disorders in the world is tinea infection. Itraconazole is still a crucial medication for treating and preventing fungal infections. Because of its wide range of action, terbinafine (TBF) is frequently
Mohammed Ewaiss, Mohamed El-khalawany, Hamed Abdo   +2 more
doaj   +1 more source

Effect of itraconazole on the quality of life in patients with moderate to severe seborrheic dermatitis: a randomized, placebo-controlled trial

Dermatology Practical & Conceptual, 2016
Background: Few studies have examined the effect of seborrheic dermatitis (SD) and/or its consequent therapy on a patient’s quality of life. Itraconazole has been suggested as an effective therapy for severe SD but its impact on Quality of Life (QoL) in ...
Zaheer Abbas, Seyede Zahra Ghodsi, Robabeh Abedeni   +2 more
doaj   +1 more source

Effects of Cytochrome P450 Inhibitors on Itraconazole and Fluconazole Induced Cytotoxicity in Hepatocytes

Journal of Toxicology, 2009
Itraconazole and fluconazole have been reported to induce hepatotoxicity in patients. The present study was designed to investigate the role of cytochrome P450 inhibitors, SKF 525A, and curcumin pretreatment on the cytotoxicity of antifungal drugs ...
Nhareet Somchit, Chong Sock Ngee, Azhar Yaakob, Zuraini Ahmad, Zainul Amiruddin Zakaria   +4 more
doaj   +1 more source

Combining derivative and synchronous approaches for simultaneous spectrofluorimetric determination of terbinafine and itraconazole [PDF]

Royal Society Open Science, 2020
In this study, determination of terbinafine and itraconazole down to biological concentration level has been carried out. The determination is based on increasing the selectivity of the spectrofluorimetric technique by combining both derivative and ...
Heba Elmansi, Aya Roshdy, Shereen Shalan, Amina El-Brashy   +3 more
doaj   +1 more source

Efficacy and safety of adding low-dose isotretinoin to itraconazole in the treatment of chronic recurrent dermatophytosis among sample of Iraqi patients: An open-labelled therapeutic clinical comparative study

Indian Journal of Dermatology, 2022
Background: An increasing number of dermatophytosis is seen now in daily clinical practice, with unusual presentations, running a chronic recurrent course and seems to be more resistant to systemic and topical conventional treatments, which necessitate ...
Dooha K Alhamdi, Khalil I Alhamdi
doaj   +1 more source

Itraconazole in dermatology

Journal of Dermatological Treatment, 1992
Itraconazole is a triazole analogue with a broad spectrum of antifungal activity, which covers yeasts and moulds. It is active against dermatophytes, candidal and pityrosporum yeasts, as well as a number of fungi which cause subcutaneous and systemic infection. It is well absorbed and has significantly fewer side-effects than systemic imidazoles. It is
openaire   +2 more sources

Antifungal Susceptibility Pattern of Non - Dermatophytic Fungi Causing Onychomycosis

Nepal Journal of Dermatology, Venereology & Leprology, 2020
Introduction: Non-dermatophytic molds (NDM) are filamentous fungi or yeast, commonly found in nature as saprophytes and plant pathogens. The incidence of onychomycosis due to NDM is 1.45 – 16.6%.
Apurva Kaushal, Pratik Gahalaut, R K Goyal, Neni Agarwal, Nitin Mishra, Madhur Kant Rastogi   +5 more
doaj   +3 more sources

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

Advanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng, Wenxia Bu, Fengxu Wang, Yueyuan Jin, Rongzhu Liu, Rui Zhao, Xuehai Wang, Mengna Jiang, Jinping Shen, Xinhang Cheng, Zuming Chen, Li Zhu, Jinlong Li, Zhenzhong Ge, Shichen Miao, Haotian Xu, Xiaoyu Zhou, Dongming Wang, Xinyuan Zhao   +18 more
wiley   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

Plant‐Derived Silver Nanoparticles From Senegalia catechu: Antimicrobial Activity and Sunlight‐Driven Photocatalysis

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Silver nanoparticles (Ag NPs) have garnered attention for their environmental and medicinal potential, emphasizing the need for eco‐friendly synthesis. This study produces Ag NPs by reacting silver nitrate with aqueous Senegalia catechu leaf extract, a reductant and stabilizer.
Devendra Khadka, Suraksha Sharma, Janaki Baral, Milan Babu Poudel, Bhoj Raj Poudel, Bishnu Prasad Bastakoti, Megh Raj Pokhrel   +6 more
wiley   +1 more source