Results 31 to 40 of about 37,692 (229)

Evaluation of Itraconazole and in Combination in the Treatment of Resistant and Recurrent Tinea Corporis and Cruris (Comparative Study) [PDF]

Al-Azhar International Medical Journal
Background: One of the most prevalent dermatological disorders in the world is tinea infection. Itraconazole is still a crucial medication for treating and preventing fungal infections. Because of its wide range of action, terbinafine (TBF) is frequently
Mohammed Ewaiss, Mohamed El-khalawany, Hamed Abdo   +2 more
doaj   +1 more source

Combining derivative and synchronous approaches for simultaneous spectrofluorimetric determination of terbinafine and itraconazole [PDF]

Royal Society Open Science, 2020
In this study, determination of terbinafine and itraconazole down to biological concentration level has been carried out. The determination is based on increasing the selectivity of the spectrofluorimetric technique by combining both derivative and ...
Heba Elmansi, Aya Roshdy, Shereen Shalan, Amina El-Brashy   +3 more
doaj   +1 more source

The Synergistic Effect of Tacrolimus (FK506) or Everolimus and Azoles Against Scedosporium and Lomentospora Species In Vivo and In Vitro

Frontiers in Cellular and Infection Microbiology, 2022
Scedosporium and Lomentospora infections in humans are generally chronic and stubborn. The use of azoles alone cannot usually inhibit the growth of these fungi.
Zikuo Wang, Mei Liu, Luyao Liu, Linyun Li, Lihua Tan, Yi Sun   +5 more
doaj   +1 more source

Effect of itraconazole on the quality of life in patients with moderate to severe seborrheic dermatitis: a randomized, placebo-controlled trial

Dermatology Practical & Conceptual, 2016
Background: Few studies have examined the effect of seborrheic dermatitis (SD) and/or its consequent therapy on a patient’s quality of life. Itraconazole has been suggested as an effective therapy for severe SD but its impact on Quality of Life (QoL) in ...
Zaheer Abbas, Seyede Zahra Ghodsi, Robabeh Abedeni   +2 more
doaj   +1 more source

Bioavailability of single-dose SUBA-itraconazole compared to conventional itraconazole under fasted and fed conditions [PDF]

, 2021
Conventional itraconazole (C-ITZ) suffers from absorption variability. SUBA-itraconazole (S-ITZ) is more bioavailable than C-ITZ at steady state in a fed condition, but there are no data comparing the two under a fasted state. An open-label, single-dose,
Rauseo, Adriana M, Burnett, Bruce, Mazi, Patrick, Spec, Andrej, Lewis, Phoebe, Mudge, Stuart, Adriana M. Rauseo, Stuart Mudge, Andrej Spec, Bruce Burnett, Patrick Mazi, Phoebe Lewis   +11 more
core   +1 more source

Effects of Cytochrome P450 Inhibitors on Itraconazole and Fluconazole Induced Cytotoxicity in Hepatocytes

Journal of Toxicology, 2009
Itraconazole and fluconazole have been reported to induce hepatotoxicity in patients. The present study was designed to investigate the role of cytochrome P450 inhibitors, SKF 525A, and curcumin pretreatment on the cytotoxicity of antifungal drugs ...
Nhareet Somchit, Chong Sock Ngee, Azhar Yaakob, Zuraini Ahmad, Zainul Amiruddin Zakaria   +4 more
doaj   +1 more source

Itraconazole in dermatology

Journal of Dermatological Treatment, 1992
Itraconazole is a triazole analogue with a broad spectrum of antifungal activity, which covers yeasts and moulds. It is active against dermatophytes, candidal and pityrosporum yeasts, as well as a number of fungi which cause subcutaneous and systemic infection. It is well absorbed and has significantly fewer side-effects than systemic imidazoles. It is
openaire   +2 more sources

Multiple Administrations of Itraconazole Increase Plasma Exposure to Pyrotinib in Chinese Healthy Adults

, 2021
Yueyue Liu, Qian Zhang, Chao Lu, Wei Hu Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University, Hefei, 230601, People’s Republic of ChinaCorrespondence: Chao Lu; Wei HuDepartment of Clinical Pharmacology, The Second ...
Liu Y, Hu W, Lu C, Zhang Q
core  

Short-Course Itraconazole in the Treatment of Candida Vulvovaginitis: A Multicentre Canadian Study

, 1996
OBJECTIVE: To determine the clinical and mycological effectiveness of oral itraconazole in the treatment of acute candida ...
Thomas W Austin, Lynette J Margesson, Canadian Itraconazole Study Group, Marc Steben, Barbara Romanowski, Marion Powell, David W Megran, Gary E Garber   +7 more
core   +1 more source

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source