Results 41 to 50 of about 113,930,362 (191)

Enhanced production of antifungal lipopeptide iturin A by Bacillus amyloliquefaciens LL3 through metabolic engineering and culture conditions optimization

Microbial Cell Factories, 2019
Background Iturins, which belong to antibiotic cyclic lipopeptides mainly produced by Bacillus sp., have the potential for application in biomedicine and biocontrol because of their hemolytic and antifungal properties.
Yulei Dang, Fengjie Zhao, Xiangsheng Liu, Xu Fan, Rui Huang, Weixia Gao, Shufang Wang, Chao Yang   +7 more
doaj   +1 more source

Table1_Enhanced production of iturin A by strengthening fatty acid synthesis modules in Bacillus amyloliquefaciens.DOCX

, 2022
Iturin A is a biosurfactant with various applications, and its low synthesis capability limits its production and application development. Fatty acids play a critical role in cellular metabolism and target product syntheses, and the relationship between ...
Shouwen Chen (3550844), Jiaming Gao (8112815), Dong Wang (73290), Zhifan Yang (8680509), Dongbo Cai (3948317), Lin Gao (344965), Min Xiong (400139), Guoming Shen (1952482), Menglin She (13764151), Jiao Shi (2545612), Min Zhang (111999)   +10 more
core   +1 more source

Iturin A Extracted From Bacillus subtilis WL-2 Affects Phytophthora infestans via Cell Structure Disruption, Oxidative Stress, and Energy Supply Dysfunction

Frontiers in Microbiology, 2020
Potato late blight, caused by Phytophthora infestans (Mont.) de Bary, represents a great food security threat worldwide and is difficult to control. Recently, Bacillus spp. have been considered biocontrol agents to control many plant diseases.
Youyou Wang, Congying Zhang, Jiao Liang, Lufang Wu, Wenbin Gao, Jizhi Jiang   +5 more
doaj   +1 more source

Precursor-directed biosynthesis of fluorinated iturin A in Bacillus spp. [PDF]

, 2009
Some iturin A-producing strains of Bacillus subtilis will elaborate the novel fluorinated analogue when incubated with 3-fluoro-L-tyrosine. The activity of iturin A is dependent on the D-tyrosine residue and the presence of fluorotyrosine may result in ...
Murphy, Cormac D., Rai, Dilip K., Clark, Benjamin R., Moran, Stephen   +3 more
core   +1 more source

Iturin A detected from liquid culture by HPLC.

, 2023
Fungal skin infections are a common condition affecting 20–25 percent of the world population. While these conditions are treatable with regular application of an antifungal medication, we sought to develop a more convenient, longer-lasting topical ...
Mark R. Prausnitz (314166), Ethan Cain (17509230), Veronica A. Montgomery (17509227), Mark P. Styczynski (692699)   +3 more
core   +1 more source

Simultaneous hydrolysis with lipase and fermentation of rapeseed cake for iturin A production by Bacillus amyloliquefaciens CX-20

BMC Biotechnology, 2019
Background Rapeseed cake (RSC), as the intermediate by-product of oil extraction from the seeds of Brassica napus, can be converted into rapeseed meal (RSM) by solvent extraction to remove oil.
Wenchao Chen, Xuan Li, Xuli Ma, Shouwen Chen, Yanping Kang, Minmin Yang, Fenghong Huang, Xia Wan   +7 more
doaj   +1 more source

Genomics-guided discovery and structure identification of cyclic lipopeptides from the Bacillus siamensis JFL15. [PDF]

PLoS ONE, 2018
In this research, a strain with broad-spectrum antimicrobial activities was isolated from the gastrointestinal tract of hairtail (Trichiurus haumela) and identified as Bacillus siamensis JFL15 through morphological, 16S rRNA, and average nucleotide ...
Ben-Hong Xu, Ya-Qin Lu, Zhi-Wei Ye, Qian-Wang Zheng, Tao Wei, Jun-Fang Lin, Li-Qiong Guo   +6 more
doaj   +1 more source

Annotated iturin A gene cluster for strain 15841.

, 2023
Fungal skin infections are a common condition affecting 20–25 percent of the world population. While these conditions are treatable with regular application of an antifungal medication, we sought to develop a more convenient, longer-lasting topical ...
Mark R. Prausnitz (314166), Ethan Cain (17509230), Veronica A. Montgomery (17509227), Mark P. Styczynski (692699)   +3 more
core   +1 more source

Target Mechanism of Iturinic Lipopeptide on Differential Expression Patterns of Defense-Related Genes against Colletotrichum acutatum in Pepper

Plants, 2022
Bacillus subtilis KB21 is an isolate with broad spectrum antifungal activity against plant pathogenic fungi. Our aim was to produce and purify antifungal lipopeptides via fermentation using B.
Joon Seong Park, Gwang Rok Ryu, Beom Ryong Kang   +2 more
doaj   +1 more source

Direct bio-utilization of untreated rapeseed meal for effective iturin A production by Bacillus subtilis in submerged fermentation. [PDF]

PLoS ONE, 2014
The feasibility of using untreated rapeseed meal as a nitrogen source for iturin A production by Bacillus subtilis 3-10 in submerged fermentation was first evaluated by comparison with two different commercial nitrogen sources of peptone and ammonium ...
Hu Jin, Xinran Zhang, Kunpeng Li, Yanxing Niu, Mian Guo, Chuanjiong Hu, Xia Wan, Yangmin Gong, Fenghong Huang   +8 more
doaj   +1 more source