Results 111 to 120 of about 3,713 (190)

Thoracolumbar Hansen Type I intervertebral disc disease in a 5 year old Dachshund

, 2008
Hansen type I intervertebral disc disease (IVDD) is a common affliction due to chronic, degenerative disc changes leading to acute clinical signs. This type of disc degeneration is most prevalent in the dachshund and other hypochondroplastic breeds ...
O'Brien, Emily C.W.
core   +1 more source

Experimental validation and comprehensive analysis of m6A methylation regulators in intervertebral disc degeneration subpopulation classification

Scientific Reports
Intervertebral disc degeneration (IVDD) is one of the most prevalent causes of chronic low back pain. The role of m6A methylation modification in disc degeneration (IVDD) remains unclear.
Xiaoqian Xu, Lianwei Shen, Yujuan Qu, Danyang Li, Xiaojing Zhao, Hui Wei, Shouwei Yue   +6 more
doaj   +1 more source

Kallikrein–kinin system as a potential target for the treatment of intervertebral disc degeneration

Intervertebral disc degeneration (IVDD) is one of the main causes of chronic low back pain (LBP) and related spinal diseases, severely affecting patients’ quality of life and imposing a considerable burden on healthcare systems.
Binglin Ye, Wanqian Zhang, Jiayu Ren, Tong Lu, Huanping Zhu, Kai Zhu, Fangjun Yang, Wei Zhu, Xiaoming Qiu, Fengqi Sun   +9 more
core   +1 more source

Metabolite-Driven Immunometabolic Crosstalk in Intervertebral Disc Degeneration: The Macrophage-Disc Cell Interface. [PDF]

J Inflamm Res
Ma D, Zhao J, Guo K, Liu W, Yin H, Zhan Y, Zhao R, Wang J, Ma T.   +8 more
europepmc   +1 more source

Ferroptosis in Intervertebral Disc Degeneration: How the Extreme Microenvironment Rewires a Cell Death Network. [PDF]

Biomedicines
Geng S, Guo H, Tian S, Miao Q, Diao Y, Wang X.   +5 more
europepmc   +1 more source

The impact of osteoporosis on the natural course and pathological evolution of intervertebral disc degeneration

Osteoporosis (OP) and intervertebral disc degeneration (IVDD) are prevalent age-related conditions. As the global population ages, the incidence of both OP and IVDD continues to rise.
Jian Wang, Binbin Tang, Yifeng Yuan, Xiaolin Shi   +3 more
core   +1 more source

Investigating potential molecular mechanisms linking 6PPD-quinone exposure to Intervertebral Disc Degeneration: A network toxicology, molecular docking, and molecular dynamics simulation study. [PDF]

PLoS One
Yang B, Wang X, Zhuo L, Chen Y, He Q.
europepmc   +1 more source

Cutting-Edge Biomaterials in Intervertebral Disc Degeneration Tissue Engineering

Intervertebral disc degeneration (IVDD) stands as the foremost contributor to low back pain (LBP), imposing a substantial weight on the world economy.
Zheng Wang, Zhang, Chuyue, Huang, Da, Taoxu Yan, Wang, Zheng, Chuyue Zhang, He, Qing, Liu, Jianheng, Yifan Wang, Qing He, Junyao Cheng, Yan, Taoxu, Jianheng Liu, Cheng, Junyao, Da Huang, Wang, Yifan   +15 more
core   +1 more source

Genetically Predicted Intervertebral Disc Degeneration and Risk of Osteoarthritis: A Two-Sample Mendelian Randomization Study with Mediation Analysis of Obesity and Sarcopenia. [PDF]

J Pain Res
Zhu J, Li Z, Zhou S, Yan J, He J.
europepmc   +1 more source

Development and Histopathological Validation of a Novel Unilateral Three-Level Lumbar Artery Ligation Model of Progressive Intervertebral Disc Degeneration. [PDF]

Orthop Rev (Pavia)
Ugur F, Sarikas N, Cinar I, Kayikci K, Albayrak M.   +4 more
europepmc   +1 more source