Results 31 to 40 of about 20,113 (176)

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

Complexin in ivermectin resistance in body lice. [PDF]

PLoS Genetics, 2018
Ivermectin has emerged as very promising pediculicide, particularly in cases of resistance to commonly used pediculicides. Recently, however, the first field-evolved ivermectin-resistance in lice was reported.
Nadia Amanzougaghene, Florence Fenollar, Claude Nappez, Amira Ben-Amara, Philippe Decloquement, Said Azza, Yassina Bechah, Eric Chabrière, Didier Raoult, Oleg Mediannikov   +9 more
doaj   +1 more source

An Attempt to Establish the Consensus Regarding the Diagnosis, Classification, and Treatment of Rosacea in Japan Using a Modified Delphi Method: The Japan Rosacea Consensus

The Journal of Dermatology, EarlyView.
ABSTRACT In Japan, rosacea has attracted increasing interest. However, because rosacea had been thought to be relatively rare in Japan, the perception of this disease varies among dermatologists. To address these challenges, this study developed a consensus regarding the diagnosis, classification, and treatment of rosacea using a modified Delphi method
Kenshi Yamasaki, Nobukazu Hayashi, Hiroaki Hayashi, Yasuko Fukuya, Yuki Horiuchi, Miwa Kobayashi, Yoshimasa Nobeyama, Jun Omatsu, Kanako Tsunoda, Yoshiki Miyachi   +9 more
wiley   +1 more source

Effects of soil physical properties on dung beetle assemblages in pasture landscapes of the Brazilian Cerrado

Agricultural and Forest Entomology, EarlyView.
We assessed the effect of the type of soil texture (loamy sand and sandy loam) and its physical properties on dung beetle species assemblages in a pastureland region of the Brazilian Cerrado. We found a reduction in the total and paracoprid beetle abundances in loamy sand soil. Furthermore, the increase of soil compaction negatively affected the entire
César Murilo de Albuquerque Correa, Renato Portela Salomão, Anderson Puker, Fernando Z. Vaz‐de‐Mello, Alfredo Raúl Abot   +4 more
wiley   +1 more source

Pemberian Ivermectin Sebelum Vaksinasi Hog Cholera Menekan Pembentukan Antibodi

Indonesia Medicus Veterinus, 2015
Penelitian ini dirancang untuk membandingkan antara titer antibodi anak babi yang diinjeksikan ivermectin, dengan titer anak babi yang tidak diberikan ivermectin.
Tri Suci Galingging, I Nyoman Suartha, Ketut Budiasa   +2 more
doaj  

Uncertainty surrounding projections of the long-term impact of ivermectin treatment on human onchocerciasis.

PLoS Neglected Tropical Diseases, 2013
BackgroundRecent studies in Mali, Nigeria, and Senegal have indicated that annual (or biannual) ivermectin distribution may lead to local elimination of human onchocerciasis in certain African foci.
Hugo C Turner, Thomas S Churcher, Martin Walker, Mike Y Osei-Atweneboana, Roger K Prichard, María-Gloria Basáñez   +5 more
doaj   +1 more source

Parasite management practices used by owners of Australian Pony Club horses and the factors influencing their decision‐making processes

Australian Veterinary Journal, EarlyView.
There is a lack of information on horse parasite management practices currently used by individual horse owners in Australia. A voluntary, anonymous online survey was developed for and distributed by Pony Club Australia to its members seeking information on horse population; housing; paddock, manure and parasite management; and owner attitudes.
W Nixon, P Buckley, R Butler
wiley   +1 more source

Early-life exposure to Ivermectin alters long-term growth and disease susceptibility.

PLoS ONE, 2021
Ivermectin is a broad-spectrum antiparasitic medicine, which is often used as a treatment for parasites or as a prophylaxis. While studies have looked at the long-term effects of Ivermectin on helminths, studies have not considered the long-term impacts ...
Taegan A McMahon, Shannon Fernandez-Denmark, Jeffrey M Grim   +2 more
doaj   +1 more source

A five-day course of ivermectin for the treatment of COVID-19 may reduce the duration of illness

International Journal of Infectious Diseases, 2021
Ivermectin, a US Food and Drug Administration-approved anti-parasitic agent, was found to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in vitro.
Sabeena Ahmed, Mohammad Mahbubul Karim, Allen G. Ross, Mohammad Sharif Hossain, John D. Clemens, Mariya Kibtiya Sumiya, Ching Swe Phru, Mustafizur Rahman, Khalequ Zaman, Jyoti Somani, Rubina Yasmin, Mohammad Abul Hasnat, Ahmedul Kabir, Asma Binte Aziz, Wasif Ali Khan   +14 more
doaj   +1 more source

Opening closed inward rectifier potassium channel doors

British Journal of Pharmacology, EarlyView.
Inwardly rectifying potassium (KIR) channels are essential regulators of membrane potential in excitable and non‐excitable tissues. Although KIR channels exhibit a biophysical preference for potassium influx due to voltage‐dependent block of outward current by polyamines and Mg2+, under physiological conditions, they predominantly mediate K+ efflux ...
Anna Stary‐Weinzinger, Fabian Kaiser, Marcel A. G. van der Heyden, Saïd Bendahhou   +3 more
wiley   +1 more source