Results 51 to 60 of about 26,766 (239)

Antimicrobial prescribing guidelines for horses in Australia

open access: yesAustralian Veterinary Journal, EarlyView.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt   +18 more
wiley   +1 more source

P2X7 receptor antagonism suppresses epileptiform‐like activity in an inflammation‐primed human iPSC‐derived neuron model of drug‐resistant epilepsy

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Neuroinflammation is increasingly recognised to contribute to drug‐resistant epilepsy. Activation of ATP‐gated P2X7 receptors has emerged as an important upstream mechanism, and increased P2X7 receptor expression is present in the seizure focus in rodent models and patients. Pharmacological antagonists of P2X7 receptors attenuate
Jaideep Kesavan   +6 more
wiley   +1 more source

How Do Morphological Traits and Abundance Reflect the Effects of Land Use Change in a Seasonal Floodable Savannah? A Dung Beetle Case in the Brazilian Pantanal

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
We investigated the effects of land‐use change on the abundance and morphological traits (body mass, pronotum ratios, protibial size, elytra ratio, and pronotum–abdomen proportion) of two dung beetle species (Dichotomius bos and D. nisus) in the Brazilian Pantanal.
Tais Felix Gonçalves   +4 more
wiley   +1 more source

Lack of efficacy of standard doses of ivermectin in severe COVID-19 patients.

open access: yesPLoS ONE, 2020
Ivermectin has recently shown efficacy against SARS-CoV-2 in-vitro. We retrospectively reviewed severe COVID-19 patients receiving standard doses of ivermectin and we compared clinical and microbiological outcomes with a similar group of patients not ...
Daniel Camprubí   +8 more
doaj   +1 more source

Poultry red mite eradication potential of ivermectin and allicin combination treatment

open access: yesVeterinary Medicine and Science, 2023
Background Existing treatments against poultry red mite (PRM; Dermanyssus gallinae) infestation have reduced efficacy or exhibit hazardous effects on chickens.
JeongWoo Kang   +2 more
doaj   +1 more source

Community‐based epilepsy care in an onchocerciasis‐endemic area: A 3‐year cohort study in Mahenge, Tanzania

open access: yesEpilepsia, Volume 66, Issue 3, Page 739-752, March 2025.
Abstract Objective In onchocerciasis‐endemic areas, limited access to antiseizure medications (ASMs) contributes to a high epilepsy burden. This study evaluated the impact of a community‐based epilepsy care program in Mahenge, Tanzania, an onchocerciasis‐endemic area with high epilepsy prevalence.
Dan Bhwana   +9 more
wiley   +1 more source

Gastric biopsies with prominent eosinophils: Clinicopathologic features and response to therapy

open access: yesHistopathology, EarlyView.
The use of the term ‘histologic eosinophilic gastritis’ (EoG) has been proposed for cases with ≥30 eosinophils/high power field (HPF) in five separate HPF and with no known associated causes of eosinophilia; however, these criteria can miss cases with clinically significant eosinophilia and our study results argue against using this term for pathology ...
Nigar Anjuman Khurram   +2 more
wiley   +1 more source

Structural model, functional modulation by ivermectin and tissue localization of Haemonchus contortus P-glycoprotein-13

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2018
Haemonchus contortus, one of the most economically important parasites of small ruminants, has become resistant to the anthelmintic ivermectin. Deciphering the role of P-glycoproteins in ivermectin resistance is desirable for understanding and overcoming
Marion David   +8 more
doaj   +1 more source

Macrofilaricidal activity after doxycycline only treatment of Onchocerca volvulus in an area of Loa loa co-endemicity: a randomized controlled trial. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2010
The risk of severe adverse events following treatment of onchocerciasis with ivermectin in areas co-endemic with loiasis currently compromises the development of control programmes and the treatment of co-infected individuals.
Joseph D Turner   +12 more
doaj   +1 more source

Evaluation of the effect of an extract of Sphingomonas xenophaga present in a Thermal Spring Water in the management of sensitive skin associated with cutaneous vascular disorder

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Inhibition of the kallikrein‐kinin system is a potential approach to the dermocosmetic treatment of skin disorders associated with redness. We showed that a cream formulation with a Sphingomonas ferment extract inhibiting this system was effective in improving vascular disorder after repeated application in female volunteers with sensitive and reactive
Pascal Hilaire   +7 more
wiley   +1 more source

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