Results 71 to 80 of about 1,005 (158)

DESIGN AND IVIVC OF LAMIVUDINE TRANSDERMAL PATCHES

The transdermal drug delivery system for lamivudine was created utilising the solvent casting method with Span-80 acting as a permeation enhancer. The drug: polymer ratios (Lamivudine: HPMC and Lamivudine: EC) were created in two different ways: one at a ratio of 1:2.5, one at a ratio of 1:5, and one with permeation enhancers.
openaire   +1 more source

Direct, differential-equation-based in-vitro–in-vivo correlation (IVIVC) method

Journal of Pharmacy and Pharmacology, 2003
Abstract A new, differential equation-based in-vitro–in-vivo correlation (IVIVC) method is proposed that directly relates the time-profiles of in-vitro dissolution rates and in-vivo plasma concentrations by using one-or multi-compartment pharmacokinetic models and a corresponding system of differential equations.
openaire   +2 more sources

Nanoparticles for drug delivery: Insight into in vitro and in vivo drug release from nanomedicines

Nano TransMed
Nanotechnology enables the achievement of the desired outcomes of nano-formulations, and the mode of drug delivery from the nanoparticles can significantly impact the efficacy of the embedded drug. This article reviews the various types of nanoparticles,
Ugochi E. Ewii, Anthony A. Attama, Emmanuel O. Olorunsola, Adaeze Linda Onugwu, Fortune Uchechukwu Nwakpa, Chioma Anyiam, Chinonye Chijioke, Toochukwu Ogbulie   +7 more
doaj   +1 more source

Application of an excipient made from chitosan and xanthan gum as a single component for the controlled release of Ambroxol

Journal of Excipients and Food Chemicals, 2016
An oral controlled release (CR) matrix system of Ambroxol hydrochloride was developed using a binary hydrophilic polymer mixture of chitosan (CH) and xanthan gum (XG) (1:1 w/w ratio).
Mayyas Al Remawi, Faisal Al-Akayleh, Mutaz S. Salem, Munther Al Shami, Adnan Badwan   +4 more
doaj  

Use of IVIVC to Optimize Generic Development

Dissolution Technologies, 2015
J.M. Cardot, G. Garrait, E. Beyssac
openaire   +1 more source

Potency Evaluation and Predictive Quality Control System Construction Strategy for Respiratory Syncytial Virus mRNA Vaccines. [PDF]

Vaccines (Basel)
Zhang S, Li C, Quan Y.
europepmc   +1 more source

Microstructural Characterization and In Vitro-In Vivo Evaluation of Drug Release and Permeation in Goupi Plaster. [PDF]

Pharmaceutics
Liu J, Guan T, Zhang A, Liu Y, Yang Z, Guan F, Li W, Wang Y.   +7 more
europepmc   +1 more source

Development of in vitro-in vivo correlation for establishing patient-centric quality standards of dissolution for lamotrigine extended-release tablets. [PDF]

Eur J Pharm Biopharm
Zidan A, Siddique AB, Shaklah M, Anand O, O'Connor T, Ashraf M.   +5 more
europepmc   +1 more source

<i>In vitro</i> and <i>in vivo</i> correlation of injectable lipid-based nanomedicines: From dissolution to protein coronas. [PDF]

Mater Today Bio
Wang H, Wu X, Wang J, Wang X, Lu Y.
europepmc   +1 more source

Heuristic approaches for IVIVC Level A

Journal of Bioequivalence & Bioavailability, 2018
openaire   +1 more source