Results 171 to 180 of about 71,442 (302)

Hepatic Safety of Orforglipron in Adults With Obesity or Overweight and/or Type 2 Diabetes: A Pooled Analysis of the Orforglipron Phase 3 Clinical Trials

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Orforglipron is a novel small‐molecule, once daily oral non‐peptide GLP‐1 receptor agonist. The hepatic safety profile in adults with obesity or overweight and/or type 2 diabetes (T2D) across seven orforglipron Phase 3 clinical trials was assessed.
Sean Wharton, Adam Stefanski, Jiaxun Chen, Girish Rao, Elvis Asare Twum, Max Denning   +5 more
wiley   +1 more source

Could a macular telangiectasia type 2-like phenotype characterize retinal JC virus infection? [PDF]

AIDS
Varenne F, Siegfried-Vergnon A, Lhomme S, Treiner E, Pignolet B, Joly M, Bonneville F, Gandia P, Rodriguez C, Cortese I, Martin-Blondel G, Soler V.   +11 more
europepmc   +1 more source

The Oncogenic Roles of JC Virus T Antigen in Breast Carcinogenesis. [PDF]

Front Mol Biosci, 2021
Zheng HC, E Y, Cui ZG, Zhao S, Zhang Y.
europepmc   +1 more source

Absence of DNA viruses in ameloblastomas

European Journal of Oral Sciences, EarlyView.
Abstract Ameloblastomas (ABs) are rare odontogenic benign tumors. Although studies of the molecular pathogenesis have revealed the presence of mutations and altered gene expression, the etiology is unresolved. Viruses cause 10%–15 % of cancers, but their potential role within benign tumors is less studied.
Maria K. Jauhiainen, Jetta Kelppe, Maria Söderlund‐Venermo, Antti A. Mäkitie, Saku T. Sinkkonen, Jaana Hagström   +5 more
wiley   +1 more source

Molecular characterization of JC virus in progressive multifocal leukoencephalopathy cases from India. [PDF]

Sci Rep
Palani GS, Telang S, Reddy V, Dhanya K, Ashwini MA, Mani RS.   +5 more
europepmc   +1 more source

Treatment of Inflammatory Bowel Disease and Pediatric Onset Multiple Sclerosis With Ocrelizumab and Ustekinumab in a JC-virus Positive Adolescent. [PDF]

JPGN Rep, 2022
Lambert-Jenkins K, Rossman I, Watson KL.
europepmc   +1 more source

Leucoencefalopatía Multifocal Progresiva causada por Virus JC

La leucoencefalopatía multifocal progresiva (LMP) es una enfermedad poco común y catastrófica que afecta la mielina, la capa protectora de los nervios en el cerebro, causando daño en la sustancia blanca cerebral.
Guayacondo, Diana Eugenia Saquicela, Wong, Teresa Layfon Jarrin, Cejido, Silvia Alexandra Aguabi, Alencastro, Jhon Alexander Ponce, Lucero, Paulette Analía Fajardo, Guerrero, Leonel Alexander Baños   +5 more
core  

Potential Role of Liver Transplantation for Child–Pugh Class A Hepatocellular Carcinoma: Prognosis and Medical Expenditure in Japan—A Retrospective Single‐Center Study

Hepatology Research, EarlyView.
Among patients with CP‐A HCC initially within the Japan criteria, some lose oncological eligibility for LT before hepatic decompensation. Further studies are needed to identify baseline factors associated with poor outcomes and to evaluate their relevance to future LT candidacy.
Akihiro Seki, Tomoyoshi Chiba, Shintaro Yagi, Rika Horii, Noboru Takata, Hiroki Nomura, Masaki Miyazawa, Tomoyuki Hayashi, Takeshi Terashima, Shinichi Nakanuma, Mitsuyoshi Okazaki, Satoshi Takada, Tatsuya Yamashita, Masao Honda, Hajime Takatori, Tetsuro Shimakami, Taro Yamashita   +16 more
wiley   +1 more source

Visual and Neuro-Ophthalmic Manifestations of John Cunningham (JC) Virus-Related Natalizumab-Associated Progressive Multifocal Leukoencephalopathy in Multiple Sclerosis: A Systematic Review. [PDF]

Cureus
Jangirashvili T, Parthiv O, Shengelia L, Tabeshadze Z, Kontchoshvili A, Waked CA, Tamer RM.   +6 more
europepmc   +1 more source

Human neurotropic polyomavirus, JC virus, late coding region encodes a novel nuclear protein, ORF4, which targets the promyelocytic leukemia nuclear bodies (PML-NBs) and modulates their reorganization. [PDF]

Virology, 2023
Saribas AS, Bellizzi A, Wollebo HS, Beer T, Tang HY, Safak M.   +5 more
europepmc   +1 more source